Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Abdul M. Mondal"'
Publikováno v:
Journal of biochemical and molecular toxicologyREFERENCES.
Conditionally reprogrammed cell (CRC) technique is a promising model for biomedical and toxicological research. In the present study, our data first demonstrated an increased level of PARP-1 in conditionally reprogrammed human foreskin keratinocytes
Autor:
Xuefeng Liu, Abdul M. Mondal
Publikováno v:
Journal of Medical Virology. 92
Autor:
Abdul M. Mondal, Xuefeng Liu
Publikováno v:
Journal of Medical Virology
Conventional cancer and transformed cell lines are widely used in cancer biology and other fields within biology. These cells usually have abnormalities from the original tumor itself, but may also develop abnormalities due to genetic manipulation, o
Autor:
Kye-Yoon Park, Katsuhiro Anami, Ana I. Robles, Abdul M. Mondal, Yukiharu Hiyoshi, Izumi Horikawa, Kaori Fujita, Manuel Serrano, Han Li, Kazunobu Isogaya, Curtis C. Harris
Publikováno v:
Cell Death & Differentiation. 24:1017-1028
p53 functions to induce cellular senescence, which is incompatible with self-renewal of pluripotent stem cells such as induced pluripotent stem cells (iPSC) and embryonic stem cells (ESC). However, p53 also has essential roles in these cells through
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2018 (2018)
BioMed Research International, Vol 2018 (2018)
The roles of protection of telomeres 1 (POT1) in human ovarian cancer have not been fully elucidated. Here, we investigated the impact of POT1 knockdown (POT1-KD) on in vitro cell proliferation, tumorigenesis, and histone deacetylase inhibitor (HDACi
Autor:
David P. Lane, Sharlyn J. Mazur, Kaori Fujita, Ettore Appella, Elsa Vera, Maria A. Blasco, Abdul M. Mondal, Sharon R. Pine, Curtis C. Harris, Izumi Horikawa, Borivoj Vojtesek, Katherine M. Morgan
Publikováno v:
Journal of Clinical Investigation
Cellular senescence contributes to aging and decline in tissue function. p53 isoform switching regulates replicative senescence in cultured fibroblasts and is associated with tumor progression. Here, we found that the endogenous p53 isoforms Δ133p53
Autor:
Masahiko Ajiro, Ana I. Robles, Chris Harris, Zhi-Ming Zheng, Kaori Fujita, Abdul M. Mondal, Stauffer Jk, Yizhe Tang, Izumi Horikawa
Publikováno v:
Oncogene. 32:2792-2798
Most human pre-mRNA transcripts are alternatively spliced, but the significance and fine-tuning of alternative splicing in different biological processes is only starting to be understood. SRSF3 (SRp20) is a member of a highly conserved family of spl
Autor:
Aaron J. Schetter, Kensuke Kumamoto, David P. Lane, Sharon R. Pine, Elise D. Bowman, Izumi Horikawa, Giang Nguyen, Borivoj Vojtesek, Ewy Mathé, Abdul M. Mondal, Jane J. Sohn, Helen Ji, Jean-Christophe Bourdon, Kaori Fujita, Curtis C. Harris
Publikováno v:
Nature Cell Biology. 11:1135-1142
The finite proliferative potential of normal human cells leads to replicative cellular senescence, which is a critical barrier to tumour progression in vivo. We show that the human p53 isoforms Delta133p53 and p53beta function in an endogenous regula
Autor:
Katsuhiro Anami, Ana I. Robles, Izumi Horikawa, Manuel Serrano, Abdul M. Mondal, Yukiharu Hiyoshi, Kaori Fujita, Kazunobu Isogaya, Han Li, Curtis C. Harris, Kye-Yoon Park
Publikováno v:
Cancer Research. 77:922-922
p53 functions to induce cellular senescence and apoptosis, which can be incompatible with self-renewal of pluripotent stem cells such as induced pluripotent stem cells (iPSC) and embryonic stem cells (ESC). On the other hand, p53 regulates DNA damage
Autor:
Yukiharu Hiyoshi, Abdul M. Mondal, David P. Lane, Izumi Horikawa, Kaori Fujita, Curtis C. Harris, Borivoj Vojtesek, Lisa M. Miller Jenkins, Ettore Appella
Publikováno v:
Nature communications. 5
Δ133p53α, a p53 isoform that can inhibit full-length p53, is downregulated at replicative senescence in a manner independent of mRNA regulation and proteasome-mediated degradation. Here we demonstrate that, unlike full-length p53, Δ133p53α is deg