Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Abdul H Fauq"'
Autor:
Lisa M Minter, Hyun Mu Shin, Mulualem E Tilahun, Ok Hyun Cho, Karthik eChandiran, Christina Arieta Kuksin, Shilpa eKeerthivasan, Abdul H Fauq, Todd E Golde, Lucio eMiele, Margot eThome, Barbara A Osborne
Publikováno v:
Frontiers in Immunology, Vol 5 (2014)
T cell stimulation requires the input and integration of external signals. Signaling through the T cell receptor (TCR) is known to induce formation of the membrane-tethered CBM complex, comprising CARMA1, BCL10 and MALT1, which is required for TCR-me
Externí odkaz:
https://doaj.org/article/f855421832f246cdb478eb6b473358a0
Autor:
Anushka eDongre, Lalitha eSurampudi, Rebecca G Lawlor, Abdul H Fauq, Lucio eMiele, Todd E Golde, Lisa M Minter, Barbara A Osborne
Publikováno v:
Frontiers in Immunology, Vol 5 (2014)
Cleavage of the Notch receptor via a γ-secretase, results in the release of the active intra-cellular domain of Notch that migrates to the nucleus and interacts with RBP-JΚ, resulting in the activation of downstream target genes. This canonical Not
Externí odkaz:
https://doaj.org/article/dd8f3770d026479d94bee87c73e1bc7d
Autor:
Malcolm A Leissring, Enrico Malito, Sabrine Hedouin, Lael Reinstatler, Tomoko Sahara, Samer O Abdul-Hay, Shakeel Choudhry, Ghulam M Maharvi, Abdul H Fauq, Malwina Huzarska, Philip S May, Sungwoon Choi, Todd P Logan, Benjamin E Turk, Lewis C Cantley, Marika Manolopoulou, Wei-Jen Tang, Ross L Stein, Gregory D Cuny, Dennis J Selkoe
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10504 (2010)
Insulin is a vital peptide hormone that is a central regulator of glucose homeostasis, and impairments in insulin signaling cause diabetes mellitus. In principle, it should be possible to enhance the activity of insulin by inhibiting its catabolism,
Externí odkaz:
https://doaj.org/article/7240b4ca7af64bf1b6cd154a5b3c1c60
Autor:
Ahsan Iqbal, Shakeel Ahmad Khan, Abdul H. Fauq, Muhammad Usman, Sohail Anjum Shahzad, Ayesha Bari, Muhammad Aamir Sajid, Zulfiqar Ali Khan
Publikováno v:
Volume: 42, Issue: 6 1518-1533
Turkish Journal of Chemistry
Turkish Journal of Chemistry
A series of new extensively conjugated $E$-stilbene azomethines (5a-5h) were synthesized and screened for their antioxidant and antimicrobial activity. The compounds were tested against bacterial (Escherichia coli, Staphylococcus aureus, Klebsiella p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f49d7f298ec2756b37b00493fafc880
https://doi.org/10.3906/kim-1801-104
https://doi.org/10.3906/kim-1801-104
Autor:
Joseph L. Johnson, Kunisi S. Venkatasubban, Jamie L. Thomas, Terrone L. Rosenberry, Abdul H. Fauq, Bernadette Cusack
Publikováno v:
Archives of Biochemistry and Biophysics. 655:67-74
Carbamates are esters of substituted carbamic acids that react with acetylcholinesterase (AChE) by initially transferring the carbamoyl group to a serine residue in the enzyme active site accompanied by loss of the carbamate leaving group followed by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb8197f69e5719fcee684546193cf42
https://doi.org/10.1016/j.abb.2018.08.006
https://doi.org/10.1016/j.abb.2018.08.006
Autor:
Chester Andrzejewski, Todd E. Golde, Lucio Miele, Emily R. Roberts, Abdul H. Fauq, Janani Srinivasan, Lisa M. Minter, Gabriela Gonzalez-Perez, Justine E. Roderick, Anushka Dongre, Christina Arieta Kuksin
Publikováno v:
The Journal of Experimental Medicine
Notch1 signaling sustains the proinflammatory behavior of Th1 cells, implicated in the development of aplastic anemia in humans and mice.
Severe aplastic anemia (AA) is a bone marrow (BM) failure (BMF) disease frequently caused by aberrant immun
Severe aplastic anemia (AA) is a bone marrow (BM) failure (BMF) disease frequently caused by aberrant immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c02d27f22de1eeaee7c3fb95f04fd2
https://doi.org/10.1084/jem.20112615
https://doi.org/10.1084/jem.20112615
Autor:
Abdul H. Fauq, Laura B. Peterson, Ahmed Chadli, Chaitanya A. Patwardhan, Charles A. Miller, Brian S. J. Blagg
Publikováno v:
Journal of Biological Chemistry. 288:7313-7325
Pharmacological inhibition of Hsp90 is an exciting option for cancer therapy. The clinical efficacy of Hsp90 inhibitors is, however, less than expected. Binding of the co-chaperone p23 to Hsp90 and induced overexpression of anti-apoptotic proteins Hs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::849681d5274249317694270b5868d756
https://doi.org/10.1074/jbc.m112.427328
https://doi.org/10.1074/jbc.m112.427328
Autor:
Nicholas F. Fitz, Muzamil Saleem, Robert Chapman, Radosveta Koldamova, Abdul H. Fauq, Iliya Lefterov, Andrea A. Cronican
Publikováno v:
The Journal of Neuroscience. 32:13125-13136
ATP-binding cassette transporter A1 (ABCA1) transporter regulates cholesterol efflux and is an essential mediator of high-density lipoprotein (HDL) formation. In amyloid precursor protein (APP) transgenic mice,Abca1deficiency increased amyloid deposi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4505ff576123aed348cf33ec2c1ddde
https://doi.org/10.1523/jneurosci.1937-12.2012
https://doi.org/10.1523/jneurosci.1937-12.2012
Publikováno v:
Behavioural Brain Research. 224:344-349
NT69L is a neurotensin (NT)(8-13) analog that binds the two major NT receptors, NTS1 and NTS2, and elicits similar behavioral effects as endogenous NT. Tolerance develops rapidly to some, but not to all of NT69L's effects, and to date, little is know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec8c354b0f4ad1ec3dc156a1bd2c699
https://doi.org/10.1016/j.bbr.2011.06.014
https://doi.org/10.1016/j.bbr.2011.06.014
Autor:
H.A. Tajmir-Riahi, P. Bourassa, Ghulam M. Maharvi, Abdul H. Fauq, Thekkumkat Thomas, S. Dubeau
Publikováno v:
Biochimie. 93:1089-1101
Tamoxifen is extensively metabolized, and several metabolites have been detected in human serum. The aim of this study was to examine the interaction of human serum albumin (HSA) with tamoxifen and its metabolites 4-hydroxytamoxifen and endoxifen at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e29049255157056ddc37d1b99e9495b
https://doi.org/10.1016/j.biochi.2011.03.006
https://doi.org/10.1016/j.biochi.2011.03.006