Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Abdul B Abou Samra"'
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0154151 (2016)
Membrane cholesterol levels play an important factor in regulating cell function. Sarcolemmal cholesterol is concentrated in lipid rafts and caveolae, which are flask-shaped invaginations of the plasma membrane. The scaffolding protein caveolin permi
Externí odkaz:
https://doaj.org/article/9b78dca4bdbe4d9aaefd45e8560a6b9c
Autor:
Mohammed Bashir, Noora Al-Thani, Mahmoud Zirie, Zaina Abdelhalim Alamer, Emad Naem, Tarik Elhadd, Wajiha Gul, Obada Salameh, Abdul B. Abou-Samra
Publikováno v:
Journal of the Endocrine Society
Introduction: Primary hyperparathyroidism (PHPT) is a common cause of hypercalcemia and mostly caused by benign solitary benign adenoma (80 to 85 %). Definite treatment is the surgical removal. The most commonly used diagnostic modalities are Sestami
Autor:
Xiangmin Zhang, Majed Alharbi, Abdullah Mallisho, Divyasri Damacharla, Danjun Ma, Anjaneyulu Kowluru, Abdul B. Abou-Samra, Wissam Al-Janabi, Yue Qi, Sorin Draghici, Zaher Msallaty, Rebecca Tagett, Griffin Calme, Michael Caruso, Zhengping Yi, Aktham Mestareehi, Berhane Seyoum
Publikováno v:
J Clin Endocrinol Metab
Context Obesity-related insulin resistance (OIR) is one of the main contributors to type 2 diabetes and other metabolic diseases. Protein kinases are implicated in insulin signaling and glucose metabolism. Molecular mechanisms underlying OIR involvin
Publikováno v:
Canadian Journal of Diabetes. 39:36-43
The interaction of immune cells with adipocytes within the adipose tissues in obese persons with diabetes mellitus may play a role in insulin resistance. We examined in vitro whether nitric oxide (NO) and inducible nitric oxide synthase (iNOS) play a
Autor:
Sara, Al-Khawaga, Bushra, Memon, Alexandra E, Butler, Shahrad, Taheri, Abdul B, Abou-Samra, Essam M, Abdelalim
Publikováno v:
Biological reviews of the Cambridge Philosophical Society. 93(1)
The loss of functional β cells leads to development of diabetes. Several studies have shown that β cells are specified through several stages of progenitors during pancreas development, each stage defined by the expression of specific transcription
Autor:
Serhiy Souchelnytskyi, Ajaz A. Bhat, Roopesh Krishnankutty, Asfar S. Azmi, Ramzi M. Mohammad, Abdul B Abou-Samra, Shahab Uddin
Publikováno v:
Journal of Proteomics & Enzymology.
Introduction: Proteomics technology is extensively used to identify the underlying molecular mechanisms of various diseases. Emergent technologies in proteomics have been used in the biomarker and drug discovery process. Proper use of this technology
Publikováno v:
Physiology Journal. 2013:1-7
We examined core body temperature (CBT) of urocortin 1 (UCN1) and corticotropin releasing factor (CRF) knockout (KO) mice exposed to 4°C for 2 h. UCN1KO mice showed higher average CBT during cold exposure as compared to WT. The CBT of male and femal
Publikováno v:
Cellular Signalling. 25:981-988
We previously have shown that Ahsg, a liver glycoprotein, inhibits insulin receptor (InsR) tyrosine kinase (TK) activity and the ERK1/2 mitogenic signaling arm of insulin signaling. Here we show that Ahsg blocks insulin-stimulated GLUT4 translocation
Publikováno v:
Biochemical and Biophysical Research Communications. 430:1126-1131
Hyperlipidemia is a major contributor to cardiovascular diseases. Members of the angiopoietin-like protein family (ANGPTLs) are important determinants of blood lipid levels. Lipasin, a newly identified gene that regulates serum triglycerides, is homo
Publikováno v:
Journal of the National Medical Association. 107(1)
Objectives The purpose of this study was to examine the rate of diabetes and pre-diabetes in previously undiagnosed individuals who came to the Detroit Receiving Hospital-Ambulatory Rapid Center (DRH-ARC), which is part of the emergency room. This re