Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Abdou Elsharawy"'
Autor:
Friederike Flachsbart, Janina Dose, Liljana Gentschew, Claudia Geismann, Amke Caliebe, Carolin Knecht, Marianne Nygaard, Nandini Badarinarayan, Abdou ElSharawy, Sandra May, Anne Luzius, Guillermo G. Torres, Marlene Jentzsch, Michael Forster, Robert Häsler, Kathrin Pallauf, Wolfgang Lieb, Céline Derbois, Pilar Galan, Dmitriy Drichel, Alexander Arlt, Andreas Till, Ben Krause-Kyora, Gerald Rimbach, Hélène Blanché, Jean-François Deleuze, Lene Christiansen, Kaare Christensen, Michael Nothnagel, Philip Rosenstiel, Stefan Schreiber, Andre Franke, Susanne Sebens, Almut Nebel
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
FOXO3 is one of the few established longevity genes. Here, the authors fine-map the FOXO3-longevity association to two intronic SNPs and, using luciferase assays and EMSAs, show that these SNPs affect binding of transcription factors CTCF and SRF and
Externí odkaz:
https://doaj.org/article/f1d90b23cde74314abd23e1b467785a0
Autor:
Friederike Flachsbart, Janina Dose, Liljana Gentschew, Claudia Geismann, Amke Caliebe, Carolin Knecht, Marianne Nygaard, Nandini Badarinarayan, Abdou ElSharawy, Sandra May, Anne Luzius, Guillermo G. Torres, Marlene Jentzsch, Michael Forster, Robert Häsler, Kathrin Pallauf, Wolfgang Lieb, Céline Derbois, Pilar Galan, Dmitriy Drichel, Alexander Arlt, Andreas Till, Ben Krause-Kyora, Gerald Rimbach, Hélène Blanché, Jean-François Deleuze, Lene Christiansen, Kaare Christensen, Michael Nothnagel, Philip Rosenstiel, Stefan Schreiber, Andre Franke, Susanne Sebens, Almut Nebel
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-2 (2018)
The original version of this Article contained an error in the spelling of the author Robert Häsler, which was incorrectly given as Robert Häesler. This has now been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/3a301166958a4d53891142c0787acc2f
Autor:
Matthias Hübenthal, Georg Hemmrich-Stanisak, Frauke Degenhardt, Silke Szymczak, Zhipei Du, Abdou Elsharawy, Andreas Keller, Stefan Schreiber, Andre Franke
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140155 (2015)
The diagnosis of inflammatory bowel disease (IBD) still remains a clinical challenge and the most accurate diagnostic procedure is a combination of clinical tests including invasive endoscopy. In this study we evaluated whether systematic miRNA expre
Externí odkaz:
https://doaj.org/article/3d87412d60bb46899a8ba58ca0e28da7
Autor:
Johannes R Hov, Verena Keitel, Jon K Laerdahl, Lina Spomer, Eva Ellinghaus, Abdou ElSharawy, Espen Melum, Kirsten M Boberg, Thomas Manke, Tobias Balschun, Christoph Schramm, Annika Bergquist, Tobias Weismüller, Daniel Gotthardt, Christian Rust, Liesbet Henckaerts, Clive M Onnie, Rinse K Weersma, Martina Sterneck, Andreas Teufel, Heiko Runz, Adolf Stiehl, Cyriel Y Ponsioen, Cisca Wijmenga, Morten H Vatn, IBSEN Study Group, Pieter C F Stokkers, Severine Vermeire, Christopher G Mathew, Benedicte A Lie, Ulrich Beuers, Michael P Manns, Stefan Schreiber, Erik Schrumpf, Dieter Häussinger, Andre Franke, Tom H Karlsen
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12403 (2010)
TGR5, the G protein-coupled bile acid receptor 1 (GPBAR1), has been linked to inflammatory pathways as well as bile homeostasis, and could therefore be involved in primary sclerosing cholangitis (PSC) a chronic inflammatory bile duct disease. We aime
Externí odkaz:
https://doaj.org/article/c775ed01a0f746309d30d3ac848ea89e
Autor:
Andre Franke, Jochen Hampe, Philip Rosenstiel, Christian Becker, Florian Wagner, Robert Häsler, Randall D Little, Klaus Huse, Andreas Ruether, Tobias Balschun, Michael Wittig, Abdou Elsharawy, Gabriele Mayr, Mario Albrecht, Natalie J Prescott, Clive M Onnie, Hélène Fournier, Tim Keith, Uwe Radelof, Matthias Platzer, Christopher G Mathew, Monika Stoll, Michael Krawczak, Peter Nürnberg, Stefan Schreiber
Publikováno v:
PLoS ONE, Vol 2, Iss 8, p e691 (2007)
Crohn disease (CD), a sub-entity of inflammatory bowel disease (IBD), is a complex polygenic disorder. Although recent studies have successfully identified CD-associated genetic variants, these susceptibility loci explain only a fraction of the herit
Externí odkaz:
https://doaj.org/article/bdae868ac4114d94b96552c5d60da968
Autor:
Andreas Keller, Arne S. Schaefer, Henrik Dommisch, Denis Bajric, Ricarda Mueller, Abdou ElSharawy, Huseyin G. Keceli
Publikováno v:
Journal of Periodontal Research. 56:1028-1036
Objective: We aimed to identify a microRNA (miRNA) that is significantly upregulated in blood and in cells of the oral mucosa upon exposure to the periodontitis main risk factors oral inflammation and tobacco smoke, to subsequently identify its targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a32dfd88efd05f43b05d9b4eeecd07
https://doi.org/10.1111/jre.12913
https://doi.org/10.1111/jre.12913
Autor:
Sarah Strohkamp, Svitlana Rozanova, Abdou ElSharawy, Christian Röder, Stefan Lehr, Jens K. Habermann, Sonja Hartwig, Holger Kalthoff, Timo Gemoll
Publikováno v:
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 10, Iss 3343, p 3343 (2021)
Journal of Clinical Medicine, Vol 10, Iss 3343, p 3343 (2021)
Solid tumor biopsies are the current standard for precision medicine. However, the procedure is invasive and not always feasible. In contrast, liquid biopsies, such as serum enriched for extracellular vesicles (EVs) represent a non-invasive source of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc622cfde5082d7fa16275ea7c87d24d
http://europepmc.org/articles/PMC8348648
http://europepmc.org/articles/PMC8348648
Autor:
Holger Kalthoff, Jens K. Habermann, Christian Röder, Svitlana Rozanova, Timo Gemoll, Sonja Hartwig, Abdou ElSharawy, Stefan Lehr
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 1429, p 1429 (2020)
Journal of Clinical Medicine
Journal of Clinical Medicine; Volume 9; Issue 5; Pages: 1429
Journal of Clinical Medicine
Journal of Clinical Medicine; Volume 9; Issue 5; Pages: 1429
Solid tumor biopsies are the current standard for precision medicine. However, the procedure is invasive and not always feasible. In contrast, liquid biopsies, such as serum enriched for extracellular vesicles (EVs) represent a non-invasive source of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c3ab1e476e22395d147d68bdd208841
https://www.mdpi.com/2077-0383/9/5/1429
https://www.mdpi.com/2077-0383/9/5/1429
Autor:
Björn Stade, Lotte Moens, Joachim Fritzsche, Sascha Sauer, Tom Brown, Xia Teng, David Stoddart, Anders Kristensen, Kalim U. Mir, Afaf H. El-Sagheer, Andre Franke, Nadine Schracke, Jonas O. Tegenfeldt, Mats Nilsson, Elin Falk-Sörqvist, Andrew John Heron, Jane Kaye, Giovanni Maglia, Nathalie Zahra, Abdou ElSharawy, Colin Veal, Rodolphe Marie, Fredrik Persson, Jonathan Mangion, Marco Mignardi, Joop M.L.M. van Helvoort, Jörg Tost, Dvir Rotem, Ivo Gut, Hagan Bayley, Achillefs N. Kapanidis, Vincent Picaud, Spencer J. Gibson, Liqin Dong, Thomas Brefort, Henrik Flyvbjerg, Markus Beier, Emile Schyns, Johannes Hohlbein, Pieter Jan Van Der Zaag, Florence Mauger, Jelle Oostmeijer, Peter Freeman, Simon Heath, Geraint Evans, Owen Lancaster, Hans Lehrach, Simone Guenther, Michael Forster, David L.V. Bauer, Rongqin Ke, Jennifer Sengenes, Steven McGinn, Jonas Nyvold Pedersen, Marta Gut, Isabelle Heath-Brun, Ludovic Le Reste, Camilla Freitag, Anthony J. Brookes, Björn Ekström, Simon Fredriksson, Mats Gullberg, Florian Mertes, James P Willcocks, Peer F. Stähler, Ruud Out, Cees Dekker
Publikováno v:
New Biotechnology, 33(3), 311-330. ELSEVIER SCIENCE BV
New Biotechnology, 33(3), 311-330
New Biotechnology 33 (2016) 3
New Biotechnology
New Biotechnology, 2016, 33 (3), pp.311-330. ⟨10.1016/j.nbt.2015.10.003⟩
New Biotechnology, 33(3), 311-330
New Biotechnology 33 (2016) 3
New Biotechnology
New Biotechnology, 2016, 33 (3), pp.311-330. ⟨10.1016/j.nbt.2015.10.003⟩
International audience; The REvolutionary Approaches and Devices for Nucleic Acid analysis (READNA) project received 12 million s funding under the European Union Framework Programme 7 from 1st June 2008 to 30th November 2012. The 19 project partners
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::affac657d3bbd8a193aed4cd37ca90f3
https://doi.org/10.1016/j.nbt.2015.10.003
https://doi.org/10.1016/j.nbt.2015.10.003
Autor:
Susanne Sebens, Marlene Jentzsch, Kaare Christensen, Michael Nothnagel, Liljana Gentschew, Sandra May, Stefan Schreiber, Hélène Blanché, Pilar Galan, Alexander Arlt, Amke Caliebe, Guillermo G. Torres, Abdou ElSharawy, Lene Christiansen, Friederike Flachsbart, Gerald Rimbach, Wolfgang Lieb, Anne Luzius, Carolin Knecht, Robert Häsler, Marianne Nygaard, Nandini Badarinarayan, Andre Franke, Jean-François Deleuze, Céline Derbois, Kathrin Pallauf, Claudia Geismann, Michael Forster, Andreas Till, Almut Nebel, Dmitriy Drichel, Janina Dose, Philip Rosenstiel, Ben Krause-Kyora
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-2 (2018)
Flachsbart, F, Dose, J, Gentschew, L, Geismann, C, Caliebe, A, Knecht, C, Nygaard, M, Badarinarayan, N, ElSharawy, A, May, S, Luzius, A, Torres, G G, Jentzsch, M, Forster, M, Häsler, R, Pallauf, K, Lieb, W, Derbois, C, Galan, P, Drichel, D, Arlt, A, Till, A, Krause-Kyora, B, Rimbach, G, Blanché, H, Deleuze, J-F, Christiansen, L, Christensen, K, Nothnagel, M, Rosenstiel, P, Schreiber, S, Franke, A, Sebens, S & Nebel, A 2018, ' Publisher Correction : Identification and characterization of two functional variants in the human longevity gene FOXO3 ', Nature Communications, vol. 9, 320 . https://doi.org/10.1038/s41467-018-02842-8
Nature Communications, Vol 9, Iss 1, Pp 1-2 (2018)
Flachsbart, F, Dose, J, Gentschew, L, Geismann, C, Caliebe, A, Knecht, C, Nygaard, M, Badarinarayan, N, ElSharawy, A, May, S, Luzius, A, Torres, G G, Jentzsch, M, Forster, M, Häsler, R, Pallauf, K, Lieb, W, Derbois, C, Galan, P, Drichel, D, Arlt, A, Till, A, Krause-Kyora, B, Rimbach, G, Blanché, H, Deleuze, J-F, Christiansen, L, Christensen, K, Nothnagel, M, Rosenstiel, P, Schreiber, S, Franke, A, Sebens, S & Nebel, A 2018, ' Publisher Correction : Identification and characterization of two functional variants in the human longevity gene FOXO3 ', Nature Communications, vol. 9, 320 . https://doi.org/10.1038/s41467-018-02842-8
FOXO3 is consistently annotated as a human longevity gene. However, functional variants and underlying mechanisms for the association remain unknown. Here, we perform resequencing of the FOXO3 locus and single-nucleotide variant (SNV) genotyping in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b55f6a9e66638237bde6135f16bcc204
https://doi.org/10.1038/s41467-018-02842-8
https://doi.org/10.1038/s41467-018-02842-8