Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Abdolsamad Borazjani"'
Publikováno v:
ACS Omega, Vol 5, Iss 45, Pp 29177-29188 (2020)
Externí odkaz:
https://doaj.org/article/29b6a731495e40ee8b46b2dc551d3c18
Autor:
Austin E. F. Sheppe, Evangel Kummari, Alyssa Walker, Angela Richards, Winnie W. Hui, Jung Hwa Lee, Lauren Mangum, Abdolsamad Borazjani, Matthew K. Ross, Mariola J. Edelmann
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Eicosanoids are cellular metabolites, which shape the immune response, including inflammatory processes in macrophages. The effects of these lipid mediators on inflammation and bacterial pathogenesis are not clearly understood. Certain eicosanoids ar
Externí odkaz:
https://doaj.org/article/8fddb9f312184990bca092871714b837
Autor:
Brittany N. Szafran, Jung Hwa Lee, Abdolsamad Borazjani, Peter Morrison, Grace Zimmerman, Kelly L. Andrzejewski, Matthew K. Ross, Barbara L.F. Kaplan
Publikováno v:
Molecules, Vol 23, Iss 12, p 3167 (2018)
Endocannabinoid-metabolizing enzymes are downregulated in response to lipopolysaccharide (LPS)-induced inflammation in mice, which may serve as a negative feedback mechanism to increase endocannabinoid levels and reduce inflammation. Increased plasma
Externí odkaz:
https://doaj.org/article/28b6a7dcdf824622b3c08854c707140c
Autor:
Brittany N. Szafran, James Nichols, Ashleigh Nicaise, Abdolsamad Borazjani, Russell L. Carr, Juliet R. Wilson, Matthew K. Ross, Barbara L.F. Kaplan
Publikováno v:
Chemico-Biological Interactions. 375:110425
Autor:
Brittany N. Szafran, Abdolsamad Borazjani, Hannah L. Scheaffer, J. Allen Crow, Ann Marie McBride, Oluwabori Adekanye, Caitlin B. Wonnacott, Richard Lehner, Barbara L. F. Kaplan, Matthew K. Ross
Publikováno v:
ACS pharmacologytranslational science. 5(10)
Carboxylesterases are members of the serine hydrolase superfamily and metabolize drugs, pesticides, and lipids. Previous research showed that inhibition of carboxylesterase 1 (CES1) in human macrophages altered the immunomodulatory effects of lipid m
Publikováno v:
The FASEB Journal. 36
Autor:
Richard Lehner, Russell L. Carr, Caitlin N Seay, Matthew K. Ross, Barbara L. F. Kaplan, Brittany N Szafran, Abdolsamad Borazjani
Publikováno v:
Chem Res Toxicol
Chlorpyrifos (CPF) is an organophosphate (OP) pesticide that causes acute toxicity by inhibiting acetylcholinesterase (AChE) in the nervous system. However, endocannabinoid (eCB) metabolizing enzymes in brain of neonatal rats are more sensitive than
Autor:
Emily Wright, Dalton Moran, S. H. Elder, Hudson Chenault, Abdolsamad Borazjani, James R Butler, Ruth Recinos, Avery J. Cooley, Paul Gloth, Katie Webb
Publikováno v:
Journal of Biomedical Materials Research Part A. 106:2251-2260
Given the limited availability of fresh osteochondral allografts and uncertainty regarding performance of decellularized allografts, this study was undertaken as part of an effort to develop an osteochondral xenograft for articular cartilage repair.
Autor:
Abdolsamad Borazjani, Evangel Kummari, Xiang Hou, Mariola J. Edelmann, Jung Hwa Lee, Matthew K. Ross
Publikováno v:
Molecular and Cellular Biochemistry. 444:125-141
The endocannabinoids (eCBs) are endogenous arachidonoyl-containing lipid mediators with important roles in host defense. Macrophages are first-line defenders of the innate immune system and biosynthesize large amounts of eCBs when activated. The cell
Publikováno v:
Can J Vet Res
The endocannabinoid (eCB) system modulates the degree of injury caused by inflammation, while enhancing the activity of phagocytes that promote resolution of inflammation and tissue repair. In-vitro studies with the monoacylglycerol lipase (MAGL) inh