Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Abdlrzag Ehdode"'
Autor:
Linda Potter, Abdlrzag Ehdode, Gerald Saldanha, Lovesh Dyall, J.H. Pringle, Nisreen Hathiari, Danielle Bury, Edward J. Hollox
Publikováno v:
Analytical Chemistry. 83:3484-3492
The purpose of this study was to evaluate whether paralogue ratio tests (PRT) using real-time PCR can accurately determine the DNA copy number (CN) using formalin fixed paraffin embedded (FFPE) tissue. Histopathology diagnostic archives are an enormo
Autor:
Linda Potter, David A. Moore, Abdlrzag Ehdode, Mohamed Z. Mughal, Lovesh Dyall, J.H. Pringle, Gerald Saldanha
Publikováno v:
The Journal of molecular diagnostics : JMD. 17(5)
Chromosomal instability is a well-described feature of malignant tumors. Melanomas have typical patterns of chromosomal instability compared with benign nevi, which have minimal DNA copy number change. A few malignant melanomas and their benign count
Autor:
Gerald Saldanha, J. Howard Pringle, David A. Moore, Lovesh Dyall, Danielle Bury, Linda Potter, Abdlrzag Ehdode
Publikováno v:
The Journal of molecular diagnostics : JMD. 15(5)
A minority of melanocytic lesions cannot confidently be classified as benign or malignant on histopathological examination, causing diagnostic uncertainty. DNA copy number changes can be used to distinguish nevi from melanoma, although the use of FFP