Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Abdikarim Abdullahi"'
Autor:
Abdikarim Abdullahi, Carly M. Knuth, Christopher Auger, Thibacg Sivayoganathan, Alexandra Parousis, Marc G. Jeschke
Publikováno v:
JCI Insight, Vol 6, Iss 16 (2021)
BACKGROUND The incidence of burn injuries in older patients is dramatically increasing as the population of older people grows. Despite the increased demand for elderly burn care, the mechanisms that mediate increased morbidity and mortality in older
Externí odkaz:
https://doaj.org/article/a01eb3d9c691406385647f9429e3c99b
Autor:
Abdikarim Abdullahi, Mile Stanojcic, Nancy Yu, Osai Samadi, Ali‐reza Sadri, Roohi Vinaik, Natalie Coburn, Marc G. Jeschke
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 6, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/5a4a49a71f4242b4a952239274125b4f
Autor:
Christopher Auger, Carly M. Knuth, Abdikarim Abdullahi, Osai Samadi, Alexandra Parousis, Marc G. Jeschke
Publikováno v:
Molecular Metabolism, Vol 29, Iss , Pp 12-23 (2019)
Objective: Browning, the conversion of white adipose tissue (WAT) to a beige phenotype, has gained interest as a strategy to induce weight loss and improve insulin resistance in metabolic disorders. However, for hypermetabolic conditions stemming fro
Externí odkaz:
https://doaj.org/article/895ff41249ce44a5af0335fc4220500a
Publikováno v:
JCI Insight, Vol 5, Iss 17 (2020)
One of the most significant adverse postburn responses is abnormal scar formation, such as keloids. Despite its prolificacy, the underlying pathophysiology of keloid development is unknown. We recently demonstrated that NLRP3 inflammasome, the master
Externí odkaz:
https://doaj.org/article/61f0308f89c04d1b856a232268dbce46
Autor:
Alexander Andersohn, M. Iveth Garcia, Ying Fan, Max C. Thompson, Askar M. Akimzhanov, Abdikarim Abdullahi, Marc G. Jeschke, Darren Boehning
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Chronic ER stress occurs when protein misfolding in the Endoplasmic reticulum (ER) lumen remains unresolved despite activation of the unfolded protein response. We have shown that traumatic injury such as a severe burn leads to chronic ER stress in v
Externí odkaz:
https://doaj.org/article/5cbebce8c3ec407f89f23bcb19ebc8a2
Autor:
David Patsouris, Peter Qi, Abdikarim Abdullahi, Mile Stanojcic, Peter Chen, Alexandra Parousis, Saeid Amini-Nik, Marc G. Jeschke
Publikováno v:
Cell Reports, Vol 13, Iss 8, Pp 1538-1544 (2015)
Burn is accompanied by long-lasting immuno-metabolic alterations referred to as hypermetabolism that are characterized by a considerable increase in resting energy expenditure and substantial whole-body catabolism. In burned patients, the length and
Externí odkaz:
https://doaj.org/article/14fa705e9f10446d8f750dc57732b731
Autor:
Marc G. Jeschke, David Patsouris, Mile Stanojcic, Abdikarim Abdullahi, Sarah Rehou, Ruxandra Pinto, Peter Chen, Marjorie Burnett, Saeid Amini-Nik
Publikováno v:
EBioMedicine, Vol 2, Iss 10, Pp 1536-1548 (2015)
Over the last decades advancements have improved survival and outcomes of severely burned patients except one population, elderly. The Lethal Dose 50 (LD50) burn size in elderly has remained the same over the past three decades, and so has morbidity
Externí odkaz:
https://doaj.org/article/4422ea24ab484217a372eab5e7376af6
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-12 (2024)
Abstract Background Tsetse flies (Glossina spp.) are the definitive biological vectors of African trypanosomes in humans and animals. Controlling this vector is the most promising method of preventing trypanosome transmission. This requires a compreh
Externí odkaz:
https://doaj.org/article/e67b2243972c4fbc8b7061e728e766e9
Publikováno v:
ImmunologyREFERENCES. 165(2)
Although sepsis in burn patients is a major contributor to mortality, treatments are not always effective and underlying mechanisms have yet to be completely elucidated. NLRP3 inflammasome orchestrates burn-induced, inflammatory-driven pathophysiolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a036462a415c50db517b7104712b8824
https://pubmed.ncbi.nlm.nih.gov/34773253
https://pubmed.ncbi.nlm.nih.gov/34773253