Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Abdi Ghaffari"'
Autor:
Sarah J. Storr, Victoria Hoskin, Radhika Aiyappa‐Maudsley, Abdi Ghaffari, Sonal Varma, Andrew Green, Emad Rakha, Ian O. Ellis, Peter A. Greer, Stewart G. Martin
Publikováno v:
Cancer Medicine, Vol 12, Iss 9, Pp 10908-10916 (2023)
Abstract Introduction The cytoskeletal protein ezrin is upregulated in many cancer types and is strongly associated with poor patient outcome. While the clinical and prognostic value of ezrin has been previously evaluated in breast cancer, most studi
Externí odkaz:
https://doaj.org/article/c970806911ed436fa210b513806aa37c
Autor:
Vern Lewis, Emma M. Bonniwell, Janelle K. Lanham, Abdi Ghaffari, Hooshmand Sheshbaradaran, Andrew B. Cao, Maggie M. Calkins, Mario Alberto Bautista-Carro, Emily Arsenault, Andre Telfer, Fatimeh-Frouh Taghavi-Abkuh, Nicholas J. Malcolm, Fatema El Sayegh, Alfonso Abizaid, Yasmin Schmid, Kathleen Morton, Adam L. Halberstadt, Argel Aguilar-Valles, John D. McCorvy
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112203- (2023)
Summary: Hallucinations limit widespread therapeutic use of psychedelics as rapidly acting antidepressants. Here we profiled the non-hallucinogenic lysergic acid diethylamide (LSD) analog 2-bromo-LSD (2-Br-LSD) at more than 33 aminergic G protein-cou
Externí odkaz:
https://doaj.org/article/2c21b545191b4d11912819fd72041816
Autor:
Abdi Ghaffari, Victoria Hoskin, Gulisa Turashvili, Sonal Varma, Jeff Mewburn, Graeme Mullins, Peter A. Greer, Friedemann Kiefer, Andrew G. Day, Yolanda Madarnas, Sandip SenGupta, Bruce E. Elliott
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-11 (2019)
Abstract Background Limited understanding of the cancer biology of metastatic sites is a major factor contributing to poor outcomes in cancer patients. The regional lymph nodes are the most common site of metastasis in most solid cancers and their in
Externí odkaz:
https://doaj.org/article/e01c03168cbb4202a2274dbf9828911d
Publikováno v:
Diagnostics, Vol 11, Iss 1, p 115 (2021)
COVID-19 pandemic will continue to pose a major public health threat until vaccination-mediated herd immunity is achieved. Most projections predict vaccines will reach a large subset of the population late in 2021 or early 2022. In the meantime, coun
Externí odkaz:
https://doaj.org/article/4c85a89906774db4ae83f4441c9f8892
Publikováno v:
Diagnostics, Vol 10, Iss 7, p 453 (2020)
In only a few months after initial discovery in Wuhan, China, SARS-CoV-2 and the associated coronavirus disease 2019 (COVID-19) have become a global pandemic causing significant mortality and morbidity and implementation of strict isolation measures.
Externí odkaz:
https://doaj.org/article/11ba1dc136bb4d88bcb8ee25b6ca6fe3
Autor:
Victoria Hoskin, Abdi Ghaffari, Brian J. Laight, Sandip SenGupta, Yolanda Madarnas, Christopher J.B. Nicol, Bruce E. Elliott, Sonal Varma, Peter A. Greer
Publikováno v:
Cancer Research Communications. 2:456-470
The main cause of cancer-associated deaths is the spread of cancer cells to distant organs. Despite its success in the primary tumor setting, modern chemotherapeutic strategies are rendered ineffective at treating metastatic disease, largely due to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e69d7b66c13b077c25f7d4c1b563cd55
https://doi.org/10.1158/2767-9764.crc-21-0117
https://doi.org/10.1158/2767-9764.crc-21-0117
Autor:
Peter A. Greer, Sonal Varma, Bruce E. Elliott, Christopher J.B. Nicol, Yolanda Madarnas, Sandip SenGupta, Brian J. Laight, Abdi Ghaffari, Victoria Hoskin
Ezrin protein expression after DOX and DTX drug challenge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd9d4a1e5ae0c69efa98ab7075b1796
https://doi.org/10.1158/2767-9764.22544618.v1
https://doi.org/10.1158/2767-9764.22544618.v1
Autor:
Peter A. Greer, Sonal Varma, Bruce E. Elliott, Christopher J.B. Nicol, Yolanda Madarnas, Sandip SenGupta, Brian J. Laight, Abdi Ghaffari, Victoria Hoskin
Common gene mutations or amplifications found in the BC cell line panel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::861e87ddec0f662cab8b413d444a43c2
https://doi.org/10.1158/2767-9764.22544615
https://doi.org/10.1158/2767-9764.22544615
Autor:
Peter A. Greer, Sonal Varma, Bruce E. Elliott, Christopher J.B. Nicol, Yolanda Madarnas, Sandip SenGupta, Brian J. Laight, Abdi Ghaffari, Victoria Hoskin
The main cause of cancer-associated deaths is the spread of cancer cells to distant organs. Despite its success in the primary tumor setting, modern chemotherapeutic strategies are rendered ineffective at treating metastatic disease, largely due to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::040c0ab51b166d763edd01a1265c45df
https://doi.org/10.1158/2767-9764.c.6550703.v1
https://doi.org/10.1158/2767-9764.c.6550703.v1
Autor:
Lori Minassian, Daniel Sanwalka, Jean-François Paré, Shannyn Macdonald-Goodfellow, R. Liam Sutherland, Abdi Ghaffari, Chelsea L. Margerum, Madhuri Koti, Andrew W.B. Craig, Tiziana Cotechini, D. Robert Siemens, Edmond Chan, Charles H. Graham
BackgroundWhile the Programmed Death 1/Programmed Death Ligand 1 (PD-1/PD-L1) immune checkpoint is an important mechanism of immune evasion in cancer, recent studies have shown that it can also lead to resistance to chemotherapy in cancer cells via r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b2f1520b79c4e047523f68f7ee90f50
https://doi.org/10.1101/2023.01.17.524124
https://doi.org/10.1101/2023.01.17.524124