Role of nitric oxide donor in methotrexate-induced testicular injury via modulation of pro-inflammatory mediators, eNOS and P-glycoprotein.

Autor: Abdelzaher, WY, Khalaf, HM, El-Hussieny, M, Bayoumi, AMA, Shehata, S, Refaie, MMM

Publikováno v: Human & Experimental Toxicology; Dec2020, Vol. 39 Issue 12, p1700-1709, 10p

Purine versus non-purine xanthine oxidase inhibitors against cyclophosphamide-induced cardiac and bone marrow toxicity in rats.

Autor: El-Sheikh, AA, Abdelzaher, WY, Gad, AA, Abdel-Gaber, SA

Publikováno v: Human & Experimental Toxicology; Mar2020, Vol. 39 Issue 3, p249-261, 13p, 3 Diagrams, 5 Charts, 1 Graph

Sirt1/Nrf2/TNFα; TLR4/Myd88/NF-κB signaling pathways are involved in mediating hepatoprotective effect of bupropion in rat model of myocardial infarction.

Autor: Abdelzaher WY; Department of Medical Pharmacology, Faculty of Medicine, Minia University, Minia 61511, Egypt., Geddawy A; Department of Medical Pharmacology, Faculty of Medicine, Minia University, Minia 61511, Egypt.; Department of Basic Medical Sciences, College of Medicine, Prince Sattam Bin Abdulaziz University, Al Kharj 11942, Saudia Arabia., Attya ME; Department of Pathology, Faculty of Medicine, Minia University, Minia 61511, Egypt., AboBakr Ali AHS; Department of Anatomy, Faculty of Medicine, Minia University, Minia 61511, Egypt., Elroby Ali D; Department of Biochemistry and molecular biology, Faculty of Pharmacy, Sohag University, Sohag, Egypt., Waggas DS; Pathological Sciences Department- MBBS Program, Fakeeh College for Medical Sciences, Jeddah 21461, Saudi Arabia., Alshaeri HK; Pharmaceutical Sciences Department- PharmD Program, Fakeeh College for Medical Sciences, Jeddah 21461, Saudi Arabia., Ibrahim YF; Department of Medical Pharmacology, Faculty of Medicine, Minia University, Minia 61511, Egypt.; Pathological Sciences Department- MBBS Program, Fakeeh College for Medical Sciences, Jeddah 21461, Saudi Arabia.

Publikováno v: Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2024 Oct 10, pp. 1-17. Date of Electronic Publication: 2024 Oct 10.

The protective effect of vinpocetine against Estradiol-benzoate induced cervical hyperkeratosis in female rats via modulation of SIRT1/Nrf2, and NLRP3 inflammasome.

Autor: Rofaeil RR; Department of Medical Pharmacology, Faculty of Medicine, Minia University, Minia, 61519, Egypt. remon.roufeal@mu.edu.eg.; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Deraya University, Minia, 61111, Egypt. remon.roufeal@mu.edu.eg., Mohyeldin RH; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Deraya University, Minia, 61111, Egypt., Sharata EE; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Deraya University, Minia, 61111, Egypt., Attya ME; Department of Pathology, Faculty of Medicine, Minia University, Minia, 61519, Egypt., Essawy H; Department of Obstetrics & Gynecology, Faculty of Medicine, Minia University, Minia, 61519, Egypt., Ibrahim OA; Department of Obstetrics & Gynecology, Faculty of Medicine, Minia University, Minia, 61519, Egypt., Abdelzaher WY; Department of Medical Pharmacology, Faculty of Medicine, Minia University, Minia, 61519, Egypt.

Publikováno v: Scientific reports [Sci Rep] 2024 Aug 19; Vol. 14 (1), pp. 19171. Date of Electronic Publication: 2024 Aug 19.

Aprepitant boasted a protective effect against olanzapine-induced metabolic syndrome and its subsequent hepatic, renal, and ovarian dysfunction; Role of IGF 1 /p-AKT/FOXO 1 and NFκB/IL-1β/TNF-α signaling pathways in female Wistar albino rats.

Autor: Mohyeldin RH; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Deraya University, Minia 61111, Egypt. Electronic address: reham.hassan@deraya.edu.eg., Abdelzaher WY; Department of Medical Pharmacology, Faculty of Medicine, Minia University, Minia 61519, Egypt. Electronic address: walaa.hamada@mu.edu.eg., Sharata EE; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Deraya University, Minia 61111, Egypt. Electronic address: ehab.essam@deraya.edu.eg., Mohamed HMA; Department of Obstetrics and Gynecology, Faculty of Medicine, Minia University, Minia 61519, Egypt., Ahmed MYM; Department of Obstetrics and Gynecology, Faculty of Medicine, Minia University, Minia 61519, Egypt., Attia JZ; Department of Anesthesia and I.C.U, Faculty of Medicine, Minia University, Minia 61519, Egypt., Atta M; Department of Anatomy, Faculty of Medicine, Minia University, Minia 61519, Egypt., Saleh RK; Department of Pathology, Faculty of Medicine, Minia University, Minia 61519, Egypt. Electronic address: Rabeh.Saleh@mu.edu.eg., Ghallab EA; Department of Biochemistry, Faculty of Pharmacy, Deraya University, Minia 61111, Egypt. Electronic address: elshimaa.amir@deraya.edu.eg., Marey H; Department of Biochemistry, Faculty of Medicine, Minia University, Minia 61519, Egypt. Electronic address: heba.ebrahim@mu.edu.eg., Elrehany MA; Department of Biochemistry, Faculty of Pharmacy, Deraya University, Minia 61111, Egypt. Electronic address: Mahmoud.elrehany@deraya.edu.eg., Rofaeil RR; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Deraya University, Minia 61111, Egypt; Department of Medical Pharmacology, Faculty of Medicine, Minia University, Minia 61519, Egypt. Electronic address: remon.roshdy@deraya.edu.

Publikováno v: Biochemical pharmacology [Biochem Pharmacol] 2024 Mar; Vol. 221, pp. 116020. Date of Electronic Publication: 2024 Jan 17.