PB1-F2 of low pathogenicity H7N7 restricts apoptosis in avian cells.

Autor: Hohensee L; Institute of Immunology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, Greifswald, Insel Riems 17493, Germany., Scheibner D; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, Greifswald, Insel Riems 17493, Germany; Institute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, Greifswald, Insel Riems 17493, Germany., Luttermann C; Institute of Immunology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, Greifswald, Insel Riems 17493, Germany., Shelton H; The Pirbright Institute, Pirbright, Ash Road, Surrey GU24 0NF, United Kingdom., Dorhoi A; Institute of Immunology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, Greifswald, Insel Riems 17493, Germany., Abdelwhab EM; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, Greifswald, Insel Riems 17493, Germany., Blohm U; Institute of Immunology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, Greifswald, Insel Riems 17493, Germany. Electronic address: Ulrike.blohm@fli.de.

Publikováno v: Virus research [Virus Res] 2024 Nov; Vol. 349, pp. 199444. Date of Electronic Publication: 2024 Aug 23.

In turkeys, unlike chickens, the non-structural NS1 protein does not play a significant role in the replication and tissue tropism of the H7N1 avian influenza virus.

Autor: Kuryshko M; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany., Landmann M; Institute of Veterinary Pathology, Faculty of Veterinary Medicine, Leipzig University, Leipzig, Germany., Luttermann C; Institute of Immunology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany., Ulrich R; Institute of Veterinary Pathology, Faculty of Veterinary Medicine, Leipzig University, Leipzig, Germany., Abdelwhab EM; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany.

Publikováno v: Virulence [Virulence] 2024 Dec; Vol. 15 (1), pp. 2379371. Date of Electronic Publication: 2024 Jul 16.

Complex N -glycans are important for interspecies transmission of H7 influenza A viruses.

Autor: Spruit CM; Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., Palme DI; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald, Germany., Li T; Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA., Ríos Carrasco M; Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., Gabarroca García A; Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., Sweet IR; Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., Kuryshko M; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald, Germany., Maliepaard JCL; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., Reiding KR; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., Scheibner D; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald, Germany., Boons G-J; Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.; Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA., Abdelwhab EM; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald, Germany., de Vries RP; Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.

Publikováno v: Journal of virology [J Virol] 2024 Apr 16; Vol. 98 (4), pp. e0194123. Date of Electronic Publication: 2024 Mar 12.

The role of PB1-F2 in adaptation of high pathogenicity avian influenza virus H7N7 in chickens.

Autor: Hohensee L; Institute of Immunology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493, Greifswald, Insel Riems, Germany.; Infection Pathogenesis, TUM School of Life Sciences, Technische Universität München, 85354, Freising, Germany., Scheibner D; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493, Greifswald, Insel Riems, Germany., Schäfer A; Institute of Immunology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493, Greifswald, Insel Riems, Germany., Shelton H; The Pirbright Institute, Pirbright, Ash Road, Surrey, GU24 0NF, UK., Mettenleiter TC; Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493, Greifswald, Insel Riems, Germany., Breithaupt A; Department of Experimental Animal Facilities and Biorisk Management, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493, Greifswald, Insel Riems, Germany., Dorhoi A; Institute of Immunology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493, Greifswald, Insel Riems, Germany., Abdelwhab EM; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493, Greifswald, Insel Riems, Germany., Blohm U; Institute of Immunology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493, Greifswald, Insel Riems, Germany. ulrike.blohm@fli.de.

Publikováno v: Veterinary research [Vet Res] 2024 Jan 03; Vol. 55 (1), pp. 5. Date of Electronic Publication: 2024 Jan 03.

Phenotypic effects of mutations observed in the neuraminidase of human origin H5N1 influenza A viruses.

Autor: Scheibner D; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany., Salaheldin AH; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany.; Department of Poultry Diseases, Faculty of Veterinary Medicine, Alexandria University, El-Beheira, Egypt., Bagato O; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany.; Center of Scientific Excellence for Influenza Viruses, National Research Centre (NRC), Water Pollution Research Department, Dokki, Giza, Egypt., Zaeck LM; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany., Mostafa A; Center of Scientific Excellence for Influenza Viruses, National Research Centre (NRC), Water Pollution Research Department, Dokki, Giza, Egypt., Blohm U; Institute of Immunology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany., Müller C; Institute of Medical Virology, Justus Liebig University Giessen, Giessen, Germany., Eweas AF; Department of Medicinal Chemistry, National Research Center, Dokki, Giza, Egypt; Department of Science, University of Technology and Applied Sciences-Rustaq, Rustaq, Sultanate of Oman., Franzke K; Institute of Infectology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany., Karger A; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany., Schäfer A; Institute of Immunology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany., Gischke M; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany., Hoffmann D; Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany., Lerolle S; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany., Li X; Centre for Biologics Evaluation, Biologics and Genetic Therapies Directorate, HPFB, Health Canada, Ottawa, ON, Canada; Department of Biochemistry, Microbiology and Immunology and Emerging Pathogens Research Centre, University of Ottawa, Ottawa, Ontario, Canada., Abd El-Hamid HS; Department of Poultry Diseases, Faculty of Veterinary Medicine, Damanhur University, Al-Buheira, Egypt., Veits J; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany., Breithaupt A; Department of Experimental Animal Facilities and Biorisk Management, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany., Boons GJ; Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Science, the Netherlands., Matrosovich M; Institute of Virology, Philipps University, Marburg, Germany., Finke S; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany., Pleschka S; Institute of Medical Virology, Justus Liebig University Giessen, Giessen, Germany.; German Center for Infection Research (DZIF) partner site Giessen-Marburg-Langen, Germany., Mettenleiter TC; Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany., de Vries RP; Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Science, the Netherlands., Abdelwhab EM; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany.

Publikováno v: PLoS pathogens [PLoS Pathog] 2023 Feb 06; Vol. 19 (2), pp. e1011135. Date of Electronic Publication: 2023 Feb 06 (Print Publication: 2023).