Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Abdelrahman H. Elsayed"'
Autor:
Abdelrahman H. Elsayed, Xueyuan Cao, Richard J. Marrero, Nam H. K. Nguyen, Huiyun Wu, Yonhui Ni, Raul C. Ribeiro, Herold Tobias, Peter J. Valk, François Béliveau, Guillaume Richard-Carpentier, Josée Hébert, C. Michel Zwaan, Alan Gamis, Edward Anders Kolb, Richard Aplenc, Todd A. Alonzo, Soheil Meshinchi, Jeffrey Rubnitz, Stanley Pounds, Jatinder K. Lamba
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-12 (2024)
Abstract In this study, we leveraged machine-learning tools by evaluating expression of genes of pharmacological relevance to standard-AML chemotherapy (ara-C/daunorubicin/etoposide) in a discovery-cohort of pediatric AML patients (N = 163; NCT001360
Externí odkaz:
https://doaj.org/article/8d2e5546c18f4cf3998b81a1211405a0
Autor:
Mohammed Elzeneini, Ahmad Mahmoud, Abdelrahman H. Elsayed, Yasmeen Taha, Lauren E. Meece, Mohammad Al-Ani, Eric I. Jeng, George J. Arnaoutakis, Juan R. Vilaro, Alex M. Parker, Juan Aranda, Jr., Mustafa M. Ahmed
Publikováno v:
American Heart Journal Plus, Vol 2, Iss , Pp 100006- (2021)
Study objective: Early bleeding is a common source of morbidity associated with left ventricular assist device (LVAD) implantation. Our objective was to identify potential predictors of peri-implant bleeding. Methods: We conducted a retrospective coh
Externí odkaz:
https://doaj.org/article/167a96e47a3147ff9f8f85af4db16fce
Autor:
Qingsong Gao, Sarra L Ryan, Ilaria Iacobucci, Pankaj S Ghate, Ruth E Cranston, Claire J Schwab, Abdelrahman H. Elsayed, Lei Shi, Stanley B Pounds, Shaohua Lei, Pradyumna Baviskar, Deqing Pei, Cheng Cheng, Matthew Bashton, Paul B Sinclair, David R Bentley, Mark Ross, Zoya Kingsbury, Terena James, Kathryn G Roberts, Meenakshi Devidas, Yiping Fan, Wenan Chen, Ti-Cheng Chang, Gang Wu, Andrew J. Carroll, Nyla A. Heerema, Virginia Valentine, Marcus B Valentine, Wenjian Yang, Jun J. Yang, Anthony V Moorman, Christine J Harrison, Charles G. Mullighan
Publikováno v:
Blood Journal.
Intrachromosomal amplification of chromosome 21 defines a subtype of high-risk childhood acute lymphoblastic leukemia (iAMP21-ALL) characterized by copy number changes and complex rearrangements of chromosome 21. The genomic basis of iAMP21-ALL and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6e66ea4f244562e6518a49d46516ddf
https://doi.org/10.1182/blood.2022019094
https://doi.org/10.1182/blood.2022019094
Autor:
Trisha Larkin, Reema Kashif, Abdelrahman H. Elsayed, Beate Greer, Karna Mangrola, Roya Raffiee, Nam Nguyen, Vivek Shastri, Biljana Horn, Jatinder K. Lamba
Publikováno v:
JCO Precision Oncology.
PURPOSE Acute lymphoblastic leukemia (ALL) is the most prevalent cause of childhood cancer and requires a long course of therapy consisting of three primary phases with interval intensification blocks. Although these phases are necessary to achieve r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da1570627b0d3b2e5ab6700c77b28ffc
https://doi.org/10.1200/po.22.00580
https://doi.org/10.1200/po.22.00580
Autor:
Abdelrahman H. Elsayed, Xueyuan Cao, Amit K. Mitra, Huiyun Wu, Susana Raimondi, Christopher Cogle, Zeina Al-Mansour, Raul C. Ribeiro, Alan Gamis, Edward Anders Kolb, Richard Aplenc, Todd A. Alonzo, Soheil Meshinchi, Jeffrey Rubnitz, Stanley Pounds, Jatinder K. Lamba
Publikováno v:
J Clin Oncol
PURPOSE To establish a patient-specific polygenic score derived from cytarabine (ara-C) pathway pharmacogenomic evaluation to personalize acute myeloid leukemia (AML) treatment. MATERIALS AND METHODS Single nucleotide polymorphisms (SNPs) in the ara-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cd11c2f0d1bfa183c487fd42f87915c
https://doi.org/10.1200/jco.21.01422
https://doi.org/10.1200/jco.21.01422
Autor:
Richard James Marrero, Xueyuan Cao, Huiyun Wu, Abdelrahman H. Elsayed, Jeffery M Klco, Raul C. Ribeiro, Jeffrey E. Rubnitz, Xiaotu Ma, Soheil Meshinchi, Richard Aplenc, E. Anders Kolb, Rhonda E Ries, Todd Alonzo, Stanley B Pounds, Jatinder Kaur Lamba
Publikováno v:
Blood Advances.
Cytarabine arabinoside (Ara-C) has been the cornerstone of AML chemotherapy for decades. Following cellular uptake, it is phosphorylated into its active triphosphate form (Ara-CTP), which primarily exerts its cytotoxic effects by inhibiting DNA synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8149bc4116c35c7ee01c3cc60a402a39
https://doi.org/10.1182/bloodadvances.2022009088
https://doi.org/10.1182/bloodadvances.2022009088
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629857
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6f51052a34c91a1c80497adb9ad9ef8
https://doi.org/10.1007/978-1-0716-2986-4_16
https://doi.org/10.1007/978-1-0716-2986-4_16
Autor:
Nam H. K. Nguyen, Roya Rafiee, Abderrahmane Tagmount, Amin Sobh, Alex Loguinov, Angelica K. de Jesus Sosa, Abdelrahman H. Elsayed, Mohammed Gbadamosi, Nathan Seligson, Christopher R. Cogle, Jeffery Rubnitz, Raul Ribeiro, James Downing, Xueyuan Cao, Stanley B. Pounds, Christopher D. Vulpe, Jatinder K. Lamba
Publikováno v:
Blood advances.
Etoposide is used to treat a wide range of malignant cancers, including acute myeloid leukemia (AML) in children. Despite the use of intensive chemotherapeutic regimens containing etoposide, a significant proportion of pediatric patients with AML bec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9f4ac829c91869cfc33faed164615f
https://pubmed.ncbi.nlm.nih.gov/36111891
https://pubmed.ncbi.nlm.nih.gov/36111891
Autor:
Mohammed O. Gbadamosi, Vivek M. Shastri, Abdelrahman H. Elsayed, Rhonda Ries, Oluwaseyi Olabige, Nam H. K. Nguyen, Angelica De Jesus, Yi-Cheng Wang, Alice Dang, Betsy A. Hirsch, Todd A. Alonzo, Alan Gamis, Soheil Meshinchi, Jatinder K. Lamba
Publikováno v:
Leukemia
Gemtuzumab ozogamicin (GO) is an anti-CD33 monoclonal antibody linked to calicheamicin, a DNA damaging agent, and is a well-established therapeutic for treating acute myeloid leukemia (AML). In this study, we used LASSO regression modeling to develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291cbb6a7f2574af2ab5aaadaa2c91ab
https://europepmc.org/articles/PMC9357169/
https://europepmc.org/articles/PMC9357169/
Autor:
Jatinder K. Lamba, Richard J Marrero, Abdelrahman H Elsayed, Xueyuan Cao, Huiyun Wu, Hiroto Inaba, Susana C. Raimondi, Ching-Hon Pui, Raul C. Ribeiro, Jeffrey E. Rubnitz, Stanley B. Pounds
Publikováno v:
Blood. 140:1039-1040
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7bcd50a550643eb5b2b7c86a6fb143e
https://doi.org/10.1182/blood-2022-159657
https://doi.org/10.1182/blood-2022-159657