Fenamates and ibuprofen as foundational components in the synthesis of innovative, targeted COX-2 anti-inflammatory drugs, undergoing thorough biopharmacological assessments and in-silico computational studies.

Autor: Elgohary MK; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Egyptian-Russian University, Badr City Cairo 11829, Egypt. Electronic address: mohamed-elgohary@eru.edu.eg., Elkotamy MS; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Egyptian-Russian University, Badr City Cairo 11829, Egypt., Abdelrahman Alkabbani M; Pharmacology and Toxicology Department, Faculty of Pharmacy, Egyptian-Russian University, Badr City, Cairo 11829, Egypt., Abdel-Aziz HA; Applied Organic Chemistry Department, National Research Center, Dokki, Cairo 12622, Egypt.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2024 Jun; Vol. 147, pp. 107393. Date of Electronic Publication: 2024 Apr 24.