Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Abdelouahid Sbai"'
Autor:
Khadija Zaki, Fatimazahra Fakir, Abdelouahid Sbai, Hamid Maghat, Mohammed Bouachrine, Tahar Lakhlifi
Publikováno v:
Current Chemistry Letters, Vol 13, Iss 3, Pp 451-466 (2024)
Protein IDO1 (indoleamine 2,3-dioxygenase) occupies a critical position in the regulation of the immune system and is involved in cancer progression and the development of immune diseases. Being a therapeutic target for such critical diseases, we aim
Externí odkaz:
https://doaj.org/article/76c6be4381ef4d0d9bf7273bcb778c57
Autor:
Soukaina Bouamrane, Ayoub Khaldan, Marwa Alaqarbeh, Abdelouahid Sbai, Mohammed Aziz Ajana, Tahar Lakhlifi, Mohammed Bouachrine, Hamid Maghat
Publikováno v:
Chemical Physics Impact, Vol 8, Iss , Pp 100502- (2024)
Fungal infections are a growing public health problem worldwide. Despite the availability of several medicines, their efficacy is still constrained by fungal resistance. This research conducted the 2D/3D-QSAR analysis on twenty-nine triazole molecule
Externí odkaz:
https://doaj.org/article/ed52f1aba3dd48468596591a87199319
Autor:
Ayoub Khaldan, Soukaina Bouamrane, Reda El-mernissi, Mohamed Ouabane, Marwa Alaqarbeh, Hamid Maghat, Mohammed Aziz Ajana, Chakib Sekkat, Mohammed Bouachrine, Tahar Lakhlifi, Abdelouahid Sbai
Publikováno v:
Arabian Journal of Chemistry, Vol 17, Iss 3, Pp 105656- (2024)
Diabetes mellitus is a chronic and non-infectious metabolic disorder caused by insufficient insulin secretion. This study investigated a set of thirty-one 4-amino-1,2,4-triazole derivatives, experimentally evaluated for their α-glucosidase activity
Externí odkaz:
https://doaj.org/article/bb0a9df2199f4b89a6c426610662e072
Autor:
Soukaina Bouamrane, Ayoub Khaldan, Marwa Alaqarbeh, Abdelouahid Sbai, Mohammed Aziz Ajana, Mohammed Bouachrine, Tahar Lakhlifi, Hamid Maghat
Publikováno v:
Arabian Journal of Chemistry, Vol 17, Iss 3, Pp 105642- (2024)
Fungal infections profoundly affect human health, causing a substantial number of infections and millions of fatalities annually on a global scale. The identification of new drugs targeting this infection is a challenge that is not yet complete. Natu
Externí odkaz:
https://doaj.org/article/e1a1625d98d74b1fa1f7ae5bc2bd83f7
Publikováno v:
Arabian Journal of Chemistry, Vol 17, Iss 1, Pp 105376- (2024)
The worldwide prevalence of cancer and its increasing frequency make it a key research area in drug discovery programs. The current research paper describes the development of QSAR models based on the in vitro against topoisomerase II, which identifi
Externí odkaz:
https://doaj.org/article/fefdeb9740c346f9a2e3e5c8b24924ce
Autor:
Mohamed OUABANE, Kamal TABTI, Halima HAJJI, Mhamed ELBOUHI, Ayoub KHALDAN, Khalid ELKAMEL, Abdelouahid SBAI, Mohammed Aziz AJANA, Chakib SEKKATE, Mohammed BOUACHRINE, Tahar LAKHLIFI
Publikováno v:
Arabian Journal of Chemistry, Vol 16, Iss 11, Pp 105207- (2023)
In this study, using both 2D-QSPR and 3D-QSPR approaches, to understand the structure-odor relationship of 78 1–4-pyrazine odorant molecules and to use this knowledge for the design of new food and flavor products. According to our results, the dev
Externí odkaz:
https://doaj.org/article/a852833650f14d338691bee2df8ef16f
Autor:
Ayoub Khaldan, Soukaina Bouamrane, Fatima En-Nahli, Reda El-mernissi, Khalil El khatabi, Rachid Hmamouchi, Hamid Maghat, Mohammed Aziz Ajana, Abdelouahid Sbai, Mohammed Bouachrine, Tahar Lakhlifi
Publikováno v:
Heliyon, Vol 7, Iss 3, Pp e06603- (2021)
Coronavirus (COVID-19), an enveloped RNA virus, primarily affects human beings. It has been deemed by the World Health Organization (WHO) as a pandemic. For this reason, COVID-19 has become one of the most lethal viruses which the modern world has ev
Externí odkaz:
https://doaj.org/article/8a6d5c27d1d14ca2940d66faf7ae6b17
Autor:
Adib Ghaleb, Adnane Aouidate, Abdelouahid Sbai, Tahar Lakhlifi, Hamid Maghat, Mouhamed Bouachrine
Publikováno v:
Orbital: The Electronic Journal of Chemistry, Vol 9, Iss 5, Pp 337-343 (2017)
A theoretical study of 1,3-cycloaddition has been carried out using density functional theory (DFT) methods at the B3LYP/6-31G* level. The regioselectivity of the reaction have been clarified through different theoretical approaches: Case of a Two-Ce
Externí odkaz:
https://doaj.org/article/1c57a18b89284aa7854c7d05284492c7
Autor:
Adnane Aouidate, Adib Ghaleb, Mounir Ghamali, Samir Chtita, M’barek Choukrad, Abdelouahid Sbai, Mohammed Bouachrine, Tahar Lakhlifi
Publikováno v:
Chemistry Central Journal, Vol 11, Iss 1, Pp 1-10 (2017)
Abstract Background Quantitative structure activity relationship was carried out to study a series of PIM1 and PIM2 inhibitors. The present study was performed on twenty-five substituted 5-(1H-indol-5-yl)-1,3,4-thiadiazols as PIM1 and PIM2 inhibitors
Externí odkaz:
https://doaj.org/article/47ae367aa30840b08d531fb8afe3bb06
Autor:
Ahmed Azaid, Rchid Kacimi, Marwa Alaqarbeh, Marzouk Raftani, Tayeb Abram, Abdelouahid Sbai, Tahar Lakhlifi, Mohammed Bouachrine
Publikováno v:
Advanced Theory and Simulations.