Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Abdelouahab Chikhi"'
Autor:
El Hassen MOKRANI, Abdelhak DJEKRIF, Soumia TENIOU, Yousra NOUADRI, Rym Gouta DEMMAK, Abdelouahab CHIKHI, Abderrahmane BENSEGUENI
Publikováno v:
South Asian Journal of Experimental Biology. 12:533-539
Transmembrane serine protease 2 (TMPRSS2) is a human protease which plays an important role in the viral life cycle. This enzyme cleaves the spike protein required for Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) viral entry at the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bdb5663d7cee01797a3c0cebed24732
https://doi.org/10.38150/sajeb.12(4).p533-539
https://doi.org/10.38150/sajeb.12(4).p533-539
Autor:
Abdelouahab Chikhi, El Hassen Mokrani, Abderrahmane Bensegueni, Sara Alrawashdeh, Mohammad A. Ghattas, Dana Emad Eddin Obaid, Ilham Boulhissa
Publikováno v:
Current Computer-Aided Drug Design. 17:214-224
Background: Considering the interesting role in the peptidoglycan biosynthesis pathway, the enzyme UDP-N-acetylglucosamine enolpyruvyl transferase is an attractive target to develop new antibacterial agents. It catalyzes the first key step of this pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8adf698c57617f52fa9215628c4ff838
https://doi.org/10.2174/1573409916666200213124929
https://doi.org/10.2174/1573409916666200213124929
Autor:
Amina Merzoug, Abdelouahab Chikhi, Amel Chefiri, Rima Khaled, Abderrahmane Bensegueni, Hanane Boucherit
Publikováno v:
Current Issues in Pharmacy and Medical Sciences, Vol 34, Iss 1, Pp 20-27 (2021)
While Alzheimer disease is the most common form of dementia, acetylcholinesterase is an interesting therapeutic target for the development of new anti-Alzheimer’s disease drugs. In order to discover potential compounds inhibiting this protein targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b67941f3778d0f719f275c9585d5844b
https://doaj.org/article/fe3cd5687cd44d3c9d0babd966f39612
https://doaj.org/article/fe3cd5687cd44d3c9d0babd966f39612
Publikováno v:
Current Enzyme Inhibition. 15:120-132
Aim and Objective: The antibacterial therapy resistance poses an urgent threat to the public’s health. Peptide deformylase is a favorable target to identify new antibiotics with novel mechanism of action. Materials and Methods: In order to discover
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1df2cbc8aefbc91edd2fb771ed9f28a
https://doi.org/10.2174/1573408015666190621095916
https://doi.org/10.2174/1573408015666190621095916
Publikováno v:
Current Enzyme Inhibition. 14:166-185
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::164a5d035a873e9c0711daf5a7b3dffa
https://doi.org/10.2174/1573408014666180626154016
https://doi.org/10.2174/1573408014666180626154016
Autor:
Hanane Boucherit, Abderrahmane Bensegueni, Jean-Michel Bolla, Abdelouahab Chikhi, Amina Merzoug
Publikováno v:
Current computer-aided drug design. 16(4)
Background: The great emergence of multi-resistant bacterial strains and the low renewal of antibiotics molecules are leading human and veterinary medicine to certain therapeutic impasses. Therefore, there is an urgent need to find new therapeutic al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3aaf6bd1c9a8fcbcccf03a12bb6dd7e
https://pubmed.ncbi.nlm.nih.gov/31244429
https://pubmed.ncbi.nlm.nih.gov/31244429
Autor:
Abdelouahab Chikhi, Hanane Boucherit, Amina Merzoug, Nousseiba Zouaghi, Abderrahmane Bensegueni, Ziani Sara
Publikováno v:
Cancer Reports and Reviews. 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12291c7bde5457f9514a0193e3535be7
https://doi.org/10.15761/crr.1000123
https://doi.org/10.15761/crr.1000123
Autor:
Soumia Teniou, Khadidja Soulef Hio, Abdelouahab Chikhi, Abderrahmane Bensegueni, Amina Merzoug, El Hassen Mokrani, Hanane Boucherit
Publikováno v:
Trends in Bioinformatics. 6:17-24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a99565e3f7c6758ed48eaf06840b234
https://doi.org/10.3923/tb.2013.17.24
https://doi.org/10.3923/tb.2013.17.24
Publikováno v:
Journal of Proteomics & Bioinformatics. :061-065
To counter increasing levels of pathogen resistance new classes of antibiotics are needed without delay. The metalloenzyme peptide deformylase (PDF) correspond to one of the most promising bacterial targets in the search for novel mode of antibiotics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dbdca706014a79d5f798337fde9a7bd
https://doi.org/10.4172/jpb.1000122
https://doi.org/10.4172/jpb.1000122
Publikováno v:
Journal of Proteomics & Bioinformatics. :161-165
Structure-based lead optimization approaches are increasingly playing a role in the drug-discovery process. Virtual screening by molecular docking has become a largely used approach to lead discovery in the pharmaceutical industry when a high-resolut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92dd8f9e78109dcc300830f4e998ecf9
https://doi.org/10.4172/jpb.1000022
https://doi.org/10.4172/jpb.1000022