Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Abdelmoula El Abbouchi"'
Publikováno v:
Results in Chemistry, Vol 6, Iss , Pp 101117- (2023)
Ethacrynic acid (EA, Edecrin) is a well-known diuretic drug used in the treatment of high blood pressure and the swelling caused by diseases such as congestive heart failure, liver failure, and kidney failure. EA has an α,β-unsaturated carbonyl uni
Externí odkaz:
https://doaj.org/article/6ea7bcd1c8884d8cb57801f35baa55fd
Autor:
Abdelmoula El Abbouchi, Khaoula Mkhayar, Souad Elkhattabi, Nabil El Brahmi, Marie-Aude Hiebel, Jérôme Bignon, Gérald Guillaumet, Franck Suzenet, Saïd El Kazzouli
Publikováno v:
Molecules, Vol 29, Iss 7, p 1437 (2024)
In the present work, the synthesis of new ethacrynic acid (EA) derivatives containing nitrogen heterocyclic, urea, or thiourea moieties via efficient and practical synthetic procedures was reported. The synthesised compounds were screened for their a
Externí odkaz:
https://doaj.org/article/fdf8dde43bea4853a0b9e3e4ad474c90
Autor:
Abdelmoula El Abbouchi, Nabil El Brahmi, Marie-Aude Hiebel, Hamza Ghammaz, Elmostafa El Fahime, Jérôme Bignon, Gérald Guillaumet, Franck Suzenet, Saïd El Kazzouli
Publikováno v:
Molecules, Vol 28, Iss 2, p 910 (2023)
The present study aims to report the design, synthesis, and biological activity of new ethacrynic acid (EA) analogs (6–10) obtained by the double modulation of the carboxylic acid moiety and the aromatic ring with the aim to increase the chemical r
Externí odkaz:
https://doaj.org/article/0781e66ac80c490283c6d670e360f1d0
Autor:
Otmane Bourzikat, Abdelmoula El Abbouchi, Hamza Ghammaz, Nabil El Brahmi, Elmostfa El Fahime, Arnaud Paris, Richard Daniellou, Franck Suzenet, Gérald Guillaumet, Saïd El Kazzouli
Publikováno v:
Molecules, Vol 27, Iss 16, p 5238 (2022)
In the present study, new 2-phenyl-5,6,7,8-tetrahydroimidazo [1,2-b]pyridazines bearing sulfonamides were synthesized, characterized and evaluated for their anticancer activities. The structures of these derivatives were elucidated by 1H NMR, 13C NMR
Externí odkaz:
https://doaj.org/article/8fc3ca29fdfa4dc9ab282d857c3b768c
Autor:
Khadija Gambouz, Abdelmoula El Abbouchi, Sarah Nassiri, Franck Suzenet, Mostapha Bousmina, Mohamed Akssira, Gérald Guillaumet, Saïd El Kazzouli
Publikováno v:
Molecules, Vol 25, Iss 12, p 2820 (2020)
The C3 direct arylation of 1H-indazole and 1H-7-azaindazole has been a significant challenge due to the lack of the reactivity at this position. In this paper, we describe a mild and an efficient synthesis of new series of C3-aryled 1H-indazoles and
Externí odkaz:
https://doaj.org/article/6aad5dbc50664a88be96b462eec6b0fd
Autor:
Sarah Nassiri, Mohamed Akssira, Abdelmoula El Abbouchi, Mostapha Bousmina, Franck Suzenet, Khadija Gambouz, Saïd El Kazzouli, Gérald Guillaumet
Publikováno v:
European Journal of Organic Chemistry. 2020:7435-7439
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc304e61ff15d74c9e5683bc5eafd469
https://doi.org/10.1002/ejoc.202001313
https://doi.org/10.1002/ejoc.202001313
Autor:
Otmane Bourzikat, Abdelmoula El Abbouchi, Ghammaz, Hamza, Brahmi, Nabil El, Elmostfa El Fahime, Paris, Arnaud, Daniellou, Richard, Suzenet, Franck, Guillaumet, Gérald, Saïd El Kazzouli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7288e9eb9e204b0b2b2916b5efa51ac
Publikováno v:
Mediterranean Journal of Chemistry, Vol 9, Iss 5, Pp 347-354 (2019)
A short and practical arylation of imidazo[1,2-a]pyridine and imidazole derivatives with aryl halides or aryl boronic acids as coupling partners was successfully carried out using phosphine-free (SIPr)Pd(allyl)Cl as the catalyst [SIPr: (N,N’-bis(2,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bad419663c39531e3cca523b8e62f3b
https://doi.org/10.13171/mjc1911271124sek
https://doi.org/10.13171/mjc1911271124sek
Autor:
Marie-Aude Hiebel, Nabil El Brahmi, Abdelmoula El Abbouchi, Franck Suzenet, Gérald Guillaumet, Jérôme Bignon, Saïd El Kazzouli
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(19)
A series of ethacrynic acid (2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid) (EA, Edecrin) containing sulfonamides linked via three types of linkers namely 1,2-ethylenediamine, piperazine and 4-aminopiperidine was synthesized and subseq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ced94e08dade48e4ed60c6b4ab3baef
https://pubmed.ncbi.nlm.nih.gov/32755677
https://pubmed.ncbi.nlm.nih.gov/32755677