Atractylodes macrocephala Koidz polysaccharide ameliorates DSS-induced colitis in mice by regulating the gut microbiota and tryptophan metabolism.

Autor: Zhang QW; State Key Laboratory of Natural Medicines, New Drug Screening and Pharmacodynamics Evaluation Center, China Pharmaceutical University, Nanjing, China., Yang MJ; State Key Laboratory of Natural Medicines, New Drug Screening and Pharmacodynamics Evaluation Center, China Pharmaceutical University, Nanjing, China., Liao CY; State Key Laboratory of Natural Medicines, New Drug Screening and Pharmacodynamics Evaluation Center, China Pharmaceutical University, Nanjing, China., Taha R; State Key Laboratory of Natural Medicines, New Drug Screening and Pharmacodynamics Evaluation Center, China Pharmaceutical University, Nanjing, China., Li QY; State Key Laboratory of Natural Medicines, New Drug Screening and Pharmacodynamics Evaluation Center, China Pharmaceutical University, Nanjing, China., Abdelmotalab MI; State Key Laboratory of Natural Medicines, New Drug Screening and Pharmacodynamics Evaluation Center, China Pharmaceutical University, Nanjing, China., Zhao SY; State Key Laboratory of Natural Medicines, New Drug Screening and Pharmacodynamics Evaluation Center, China Pharmaceutical University, Nanjing, China., Xu Y; State Key Laboratory of Natural Medicines, New Drug Screening and Pharmacodynamics Evaluation Center, China Pharmaceutical University, Nanjing, China., Jiang ZZ; State Key Laboratory of Natural Medicines, New Drug Screening and Pharmacodynamics Evaluation Center, China Pharmaceutical University, Nanjing, China., Chu CH; State Key Laboratory of Natural Medicines, New Drug Screening and Pharmacodynamics Evaluation Center, China Pharmaceutical University, Nanjing, China., Huang X; State Key Laboratory of Natural Medicines, New Drug Screening and Pharmacodynamics Evaluation Center, China Pharmaceutical University, Nanjing, China., Jiao CH; Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Sun LX; State Key Laboratory of Natural Medicines, New Drug Screening and Pharmacodynamics Evaluation Center, China Pharmaceutical University, Nanjing, China.

Publikováno v: British journal of pharmacology [Br J Pharmacol] 2024 Dec 12. Date of Electronic Publication: 2024 Dec 12.

Dihydromyricetin alleviates inflammatory bowel disease associated intestinal fibrosis by inducing autophagy through the PI3K/AKT/mTOR signaling pathway.

Autor: Wang, XiaoChun, Li, XiaoLi, Ma, XueNi, Zhang, LuDan, Han, TiYun, Zhang, DeKui

Publikováno v: Naunyn-Schmiedeberg's Archives of Pharmacology; Jun2024, Vol. 397 Issue 6, p4183-4194, 12p

TAK1 inhibition improves myoblast differentiation and alleviates fibrosis in a mouse model of Duchenne muscular dystrophy.

Autor: Xu, Dengqiu, Li, Sijia, Wang, Lu, Jiang, Jingwei, Zhao, Lei, Huang, Xiaofei, Sun, Zeren, Li, Chunjie, Sun, Lixin, Li, Xihua, Jiang, Zhenzhou, Zhang, Luyong

Publikováno v: Journal of Cachexia, Sarcopenia & Muscle; Feb2021, Vol. 12 Issue 1, p192-208, 17p