Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Abdelilah Soussi-Gounni"'
Autor:
Omer Qibi, Severine Audusseau, Andrea Mogas, Zoulfia Allakhverdi, Abdelilah Soussi Gounni, Saba Al Heialy, Qutayba Hamid
Publikováno v:
AIMS Allergy and Immunology, Vol 2, Iss 4, Pp 165-179 (2018)
Immunoglobulin E (IgE) plays an important role in the pathogenesis of asthma and anti-IgE therapy was approved for treating patients with severe persistent allergic asthma. The exact target sites of anti-IgE therapy are not well characterized; howeve
Externí odkaz:
https://doaj.org/article/6fe2e06431db4d309589e3802b2ecdf6
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
African trypanosomiasis (sleeping sickness) poses serious threat to human and animal health in sub-Saharan Africa. Because there is currently no vaccine for preventing this disease and available drugs are not safe, understanding the mechanisms that r
Externí odkaz:
https://doaj.org/article/56374ff6a57a4bddbb7ba42d87a6e06b
Publikováno v:
American journal of respiratory cell and molecular biology. 66(6)
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
Pentraxin-3 (PTX3), is a soluble pattern recognition receptor (PRR) and constitutes humoral component of the innate immune system. It interacts with pathogenic moieties, infected and dying host cells and facilitates their removal through activation o
Externí odkaz:
https://doaj.org/article/20299a6dc1724b679bc13b85b76fad9b
Autor:
Gaurav Gupta, Ping Jia, Rohit Sharma, Romaniya Zayats, Lianyu Shan, Zhirong Mou, Thomas Murooka, Abdelilah Soussi-Gounni, Camila I de Oliveira, Jude E Uzonna
Publikováno v:
The Journal of Immunology. 202:190.21-190.21
Resolution of cutaneous leishmaniasis (CL), caused by the protozoan parasite Leishmania (L) major, relies on the nature of the host immune response. The long pentraxin 3 (PTX3), a soluble pattern recognition molecule, is critical for wound healing by
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 291:L312-L321
The airway smooth muscle (ASM) has been typically described as a contractile tissue, responding to neurotransmitters and inflammatory mediators. However, it has recently been recognized that ASM cells can also secrete cytokines and chemokines and exp
Publikováno v:
Journal of Allergy and Clinical Immunology. 107:575-582
Considerable evidence from both human and animal studies indicates that CD4(+) cells are the predominant cell type involved in the regulation of airway inflammation through the expression of T(H)2-type cytokines. The effects of T(H)2-type cytokines,
Autor:
Abdelilah Soussi Gounni, Bouchaib Lamkhioued, Latifa Koussih, Chisei Ra, Paolo M. Renzi, Qutayba Hamid
Publikováno v:
The FASEB Journal. 15:940-949
Autor:
Abdelilah Soussi-Gounni, Anuradha Ray, Omar Ghaffar, Rame Taha, Qutayba Hamid, Ronald Olivenstein, Dong-Hong Zhang, Yutaka Nakamura
Publikováno v:
Scopus-Elsevier
High expression of IL-5 by T cells in the airways of asthmatic individuals is believed to play a fundamental role in the eosinophilia associated with this disease. Recently, the transcription factor GATA-3 was shown to be critical for IL-5 gene expre
Autor:
Bruce Mazer, Ehssan Sharif-Askari, Abdelilah Soussi-Gounni, Q. Hamid, Lama M. Fawaz, O. Hajoui
Publikováno v:
The Journal of allergy and clinical immunology. 120(5)
Background IL-9 has been shown to affect the differentiation pathway of different cell types. However, its potential role in the maturation pathway of antigen-driven B-cell differentiation and its functional effects remain unknown. Objective To chara