Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Abdelilah, Majdoubi"'
Autor:
Manik Kuchroo, Marcello DiStasio, Eric Song, Eda Calapkulu, Le Zhang, Maryam Ige, Amar H. Sheth, Abdelilah Majdoubi, Madhvi Menon, Alexander Tong, Abhinav Godavarthi, Yu Xing, Scott Gigante, Holly Steach, Jessie Huang, Guillaume Huguet, Janhavi Narain, Kisung You, George Mourgkos, Rahul M. Dhodapkar, Matthew J. Hirn, Bastian Rieck, Guy Wolf, Smita Krishnaswamy, Brian P. Hafler
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Due to commonalities in pathophysiology, age-related macular degeneration (AMD) represents a uniquely accessible model to investigate therapies for neurodegenerative diseases, leading us to examine whether pathways of disease progression are
Externí odkaz:
https://doaj.org/article/7d518075ed264723a3afcab7d1e39ef3
Autor:
Abdelilah Majdoubi, Christina Michalski, Sarah E. O’Connell, Sarah Dada, Sandeep Narpala, Jean Gelinas, Disha Mehta, Claire Cheung, Dirk F.H. Winkler, Manjula Basappa, Aaron C. Liu, Matthias Görges, Vilte E. Barakauskas, Mike Irvine, Jennifer Mehalko, Dominic Esposito, Inna Sekirov, Agatha N. Jassem, David M. Goldfarb, Steven Pelech, Daniel C. Douek, Adrian B. McDermott, Pascal M. Lavoie
Publikováno v:
JCI Insight, Vol 6, Iss 8 (2021)
Preexisting cross-reactivity to SARS-CoV-2 occurs in the absence of prior viral exposure. However, this has been difficult to quantify at the population level due to a lack of reliably defined seroreactivity thresholds. Using an orthogonal antibody t
Externí odkaz:
https://doaj.org/article/8fd1fd8cfc51413a8d680753e700f8ec
Autor:
Abdelilah Majdoubi, Jun Seong Lee, Osama A. Kishta, Mohammad Balood, Mohamed Abdelwafi Moulefera, Satoshi Ishido, Sébastien Talbot, Cheolho Cheong, Thierry Alquier, Jacques Thibodeau
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Obesity is a major risk factor for the development of insulin resistance and type 2 diabetes. However, the mechanisms that trigger the underlying adipose tissues inflammation are not completely understood. Here, we show that the E3 ubiquitin ligase M
Externí odkaz:
https://doaj.org/article/05ca7d4f09584924be320d026703f95e
Autor:
Frederic Reicherz, Rui Yang Xu, Bahaa Abu-Raya, Abdelilah Majdoubi, Christina Michalski, Liam Golding, Aleksandra Stojic, Marina Vineta, Madison Granoski, Zenon Cieslak, Anil Chacko, Neil Desai, Inna Sekirov, David J Marchant, Pascal M Lavoie
Publikováno v:
The Journal of Infectious Diseases. 226:2064-2068
Health jurisdictions have seen a near-disappearance of respiratory syncytial virus (RSV) during the first year of the coronavirus disease 2019 (COVID-19) pandemic. Over this corresponding period, we report a reduction in RSV antibody levels and live
Autor:
Osama A. Kishta, Antoine Sabourin, Leora Simon, Toby McGovern, Maxime Raymond, Tristan Galbas, Abdelilah Majdoubi, Satoshi Ishido, James G. Martin, Jacques Thibodeau
Publikováno v:
Journal of Immunology Research, Vol 2018 (2018)
Membrane-associated RING-CH-1 (March1) is a member of the March family of E3 ubiquitin ligases. March1 downregulates cell surface expression of MHC II and CD86 by targeting them to lysosomal degradation. Given the key roles of MHC class II and CD86 i
Externí odkaz:
https://doaj.org/article/f4d7a20688454d35a71b3a38a55e39c3
Autor:
Genelle R. Healey, Liam Golding, Alana Schick, Abdelilah Majdoubi, Pascal M. Lavoie, Bruce A. Vallance
ObjectiveLittle is known about the interplay between gut microbiome and SARS-CoV-2 vaccine immunogenicity. In this prospective observational study, we investigated associations between the gut microbiome, habitual dietary fibre intake, and mRNA vacci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cd3efd437e8e65abe9aff4c161a72df
https://doi.org/10.1101/2022.08.24.22279143
https://doi.org/10.1101/2022.08.24.22279143
Autor:
Harjeev Sudan, Frederic Reicherz, Liam Golding, Zahra Jama Shire, Paul N Levett, Pascal M. Lavoie, Abdelilah Majdoubi, Sally Lawrence, Kevan Jacobson
Publikováno v:
Gut. 71:1922-1924
Autor:
Frederic, Reicherz, Rui Yang, Xu, Bahaa, Abu-Raya, Abdelilah, Majdoubi, Christina, Michalski, Liam, Golding, Aleksandra, Stojic, Marina, Vineta, Madison, Granoski, Zenon, Cieslak, Anil, Chacko, Neil, Desai, Inna, Sekirov, David J, Marchant, Pascal M, Lavoie
Publikováno v:
The Journal of infectious diseases.
Health jurisdictions have seen a near-disappearance of Respiratory Syncytial Virus (RSV) during the first year of the COVID-19 pandemic. Over a corresponding period, we report a reduction in RSV antibody levels and neutralization in women and infants
Autor:
Auriane DeMontigny, Tristan Galbas, Tae Jin Yun, Mohammad Balood, Cheolho Cheong, Jun Seong Lee, Sébastien Talbot, Jacques Thibodeau, Osama A Kishta, Satoshi Ishido, Antoine Sabourin, Abdelilah Majdoubi, Mohamed Abdelwafi Moulefera
Publikováno v:
The Journal of Immunology. 203:2887-2898
Dendritic cells (DCs) are critical players in skin homeostasis. A subset of mannose receptor (CD206)–expressing monocyte-derived DCs was found in skin, and their migratory counterpart is present in skin-draining lymph nodes (sdLNs). Skin CD206+ DCs