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Total marrow irradiation reduces organ damage and enhances tissue repair with the potential to increase the targeted dose of bone marrow in both young and old mice.

Autor: Ji Eun Lim, Madabushi, Srideshikan Sargur, Vishwasrao, Paresh, Song, Joo Y., Abdelhamid, Amr M. H., Ghimire, Hemendra, Vanishree, V. L., Lamba, Jatinder K., Dandapani, Savita, Salhotra, Amandeep, Lemecha, Mengistu, Pierini, Antonio, Daohong Zhao, Storme, Guy, Holtan, Shernan, Aristei, Cynthia, Schaue, Dorthe, Al Malki, Monzr, Hui, Susanta K.

Publikováno v: Frontiers in Oncology; 11/10/2022, Vol. 12, p1-13, 13p

Development and characterization of a preclinical total marrow irradiation conditioning-based bone marrow transplant model for sickle cell disease.

Autor: Sargur Madabushi S; Department of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, United States., Fouda R; Department of Medicine, Division of Hematology/Oncology, University of California, Irvine, CA, United States., Ghimire H; Department of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, United States., Abdelhamid AMH; Department of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, United States.; Radiation Oncology Section, Department of Medicine and Surgery, Perugia University and General Hospital, Perugia, Italy.; Department of Clinical Oncology and Nuclear Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Lim JE; Department of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, United States., Vishwasrao P; Department of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, United States., Kiven S; Department of Medicine, Division of Hematology/Oncology, University of California, Irvine, CA, United States., Brooks J; Department of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, United States.; Department of Radiation Oncology, Mayo Clinic, Rochester, MN, United States., Zuro D; Department of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, United States.; Department of Radiation Oncology, University of Oklahoma Health Sciences Center (HSC), Oklahoma City, OK, United States., Rosenthal J; Department of Pediatrics, City of Hope National Medical Center, Duarte, CA, United States., Guha C; Department of Radiation Oncology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, United States., Gupta K; Department of Medicine, Division of Hematology/Oncology, University of California, Irvine, CA, United States.; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, United States.; Southern California Institute for Research and Education, Veterans Affairs (VA) Medical Center, Long Beach, CA, United States., Hui SK; Department of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, United States.

Publikováno v: Frontiers in oncology [Front Oncol] 2022 Sep 06; Vol. 12, pp. 969429. Date of Electronic Publication: 2022 Sep 06 (Print Publication: 2022).