Implementing losartan potassium-laden pegylated nanocubic vesicles as a novel nanoplatform to alleviate cisplatin-induced nephrotoxicity via blocking apoptosis and activating the wnt/β-catenin/TCF-4 pathway.

Autor: Salem HF; Pharmaceutics and Industrial Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt. Electronic address: heba.salim@pharm.bsu.edu.eg., Nafady MM; Pharmaceutics and Industrial Pharmacy Department, Faculty of Pharmacy, Nahda University Beni-Suef, Egypt. Electronic address: mohamed.abdelfatah@nub.edu.eg., Khallaf RA; Pharmaceutics and Industrial Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt. Electronic address: Rasha.mahmoud@pharm.bsu.edu.eg., Abdel-Sattar AR; Pharmacology and Toxicology Department, Faculty of Pharmacy, Nahda University, Beni-Suef, Egypt. Electronic address: asmaa.ramdan@nub.edu.eg., Abdel-Sattar HH; Pharmaceutics and Industrial Pharmacy Department, Faculty of Pharmacy, Nahda University Beni-Suef, Egypt. Electronic address: hend.abdelsatar@nub.edu.eg., Eissa EM; Pharmaceutics and Industrial Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt. Electronic address: essam.mohamed@pharm.bsu.edu.eg.

Publikováno v: Life sciences [Life Sci] 2024 Oct 01; Vol. 354, pp. 122955. Date of Electronic Publication: 2024 Aug 08.