Acacia saligna extract alleviates quetiapine-induced sexual toxicity in male albino rats: Insights from UPLC-MS/MS metabolite profiling, structural and PI3K/NF-κB pathway assessments.

Autor: Yousof SM; Medical Physiology Department, Faculty of Medicine, King Abdulaziz University, Rabigh Branch, 21589, Saudi Arabia.; Medical Physiology Department, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt.; Neuroscience and Geroscience Unit, King Fahad Research Centre, King Abdulaziz University, KSA., Shehata SA; Forensic Medicine and Clinical Toxicology Department, Faculty of Medicine- Suez Canal University, Ismailia, 41522, Egypt., Ismail EA; Urology Department, Faculty of Medicine, Suez Canal University, Ismailia, 41522, Egypt., Abd El-Moneam SM; Human Anatomy and Embryology, Faculty of Medicine, Suez Canal University, Ismailia, 41522, Egypt., Mansour BSA; Human Anatomy and Embryology, Faculty of Medicine, Suez Canal University, Ismailia, 41522, Egypt., Farag MA; Pharmacognosy Department, College of Pharmacy, Cairo University, Kasr el Aini, Giza 12613, Egypt., Elshamy AI; Department of Natural Compounds Chemistry, National Research Center, Dokki, Giza 12622, Egypt., El-Nasser G El Gendy A; Medicinal and Aromatic Plants Research Department, National Research Centre, 33 El Bohouth St., Dokki, Giza, 12622, Egypt., Serag A; Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Al-Azhar University, Cairo, 11751, Egypt., Abd El-Fadeal NM; Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Suez Canal University, Ismailia, 41522, Egypt.; Biochemistry Department, Ibn Sina National College for Medical Studies, Jeddah, 22421, Saudi Arabia., Abdel-Karim RI; Forensic Medicine and Clinical Toxicology Department, Faculty of Medicine- Suez Canal University, Ismailia, 41522, Egypt., Mostafa MM; Clinical Biochemistry Department, Faculty of Medicine, King Abdulaziz University, Rabigh Branch, 21589, Saudi Arabia.; Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Cairo University, Kasr Al Ainy, Cairo, 11562, Egypt., El-Sheikh DH; Pharmacognosy Department, College of Pharmacy, Cairo University, Kasr el Aini, Giza 12613, Egypt.; Medical Physiology Department, Faculty of Medicine, Prince Sattam Bin Abdulaziz University, Al Kharj Branch, 16273, Saudi Arabia.; Medical Physiology Department, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt., Zayed MA; Medical Physiology Department, Faculty of Medicine, King Abdulaziz University, Rabigh Branch, 21589, Saudi Arabia.; Medical Physiology Department, Faculty of Medicine, Menoufia University, Menoufia, 13829, Egypt.; Neuroscience and Geroscience Unit, King Fahad Research Centre, King Abdulaziz University, KSA.

Publikováno v: Heliyon [Heliyon] 2024 Jul 03; Vol. 10 (13), pp. e33993. Date of Electronic Publication: 2024 Jul 03 (Print Publication: 2024).

Alleviation of doxorubicin-induced cardiotoxicity in rat by mesenchymal stem cells and olive leaf extract via MAPK/ TNF-α pathway: Preclinical, experimental and bioinformatics enrichment study.

Autor: Ibrahim MA; Department of Internal Medicine (Forensic Medicine and Clinical Toxicology division), College of Medicine, Jouf University, Aljouf 72341, Saudi Arabia. Electronic address: mabdulbaset@ju.edu.sa., Khalifa AM; Pathology Department, College of Medicine, Jouf University, Aljouf, Saudi Arabia., Abd El-Fadeal NM; Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt; Center of Excellence in Molecular and Cellular Medicine, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt; Oncology Diagnostic Unit, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt., Abdel-Karim RI; Forensic Medicine and Clinical Toxicology Department, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt., Elsharawy AF; Histology Department, Faculty of Medicine Al-Azhar University, Cairo, Egypt; Histology Department, College of Medicine, Shaqra University, Shaqra, Saudi Arabia., Ellawindy A; Medical Genetics Unit, Department of Histology and Cell Biology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt., Galal HM; Department of Medical Physiology, College of Medicine, Jouf University, Sakaka, Saudi Arabia; Department of Medical Physiology, Faculty of Medicine, Assiut University, Assiut, Egypt., Nadwa EH; Department of Pharmacology and Therapeutics, College of Medicine, Jouf University, Sakaka 72345, Saudi Arabia; Department of Medical Pharmacology, Faculty of Medicine, Cairo University, Giza 12613, Egypt., Abdel-Shafee MA; Department of Cardiovascular Medicine, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt., Galhom RA; Center of Excellence in Molecular and Cellular Medicine, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt; Human Anatomy and Embryology Department, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt; Human Anatomy and Embryology Department, Faculty of Medicine, Badr University in Cairo (BUC), Cairo 11829, Egypt.

Publikováno v: Tissue & cell [Tissue Cell] 2023 Dec; Vol. 85, pp. 102239. Date of Electronic Publication: 2023 Oct 10.