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Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes.

Autor: Maghraby MT; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt., Abou-Ghadir OMF; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt., Abdel-Moty SG; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt., Ali AY; Histology and Cell Biology Department, Faculty of Medicine, Assiut University, Assiut 71111, Egypt., Salem OIA; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt. Electronic address: ola.salim@pharm.aun.edu.eg.

Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2020 Apr 01; Vol. 28 (7), pp. 115403. Date of Electronic Publication: 2020 Feb 26.

Synthesis and anti-HSV activity of tricyclic penciclovir and hydroxybutylguanine derivatives.

Autor: Mohammed AF; School of Pharmacy & Pharmaceutical Sciences, Cardiff University, King Edward VII Avenue, Cardiff CF10 3NB, UK; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt., Andrei G; Rega Institute for Medical Research, KU Leuven, Herestraat 49 Box 1030, Leuven 3000, Belgium., Hayallah AM; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt., Abdel-Moty SG; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt., Snoeck R; Rega Institute for Medical Research, KU Leuven, Herestraat 49 Box 1030, Leuven 3000, Belgium., Simons C; School of Pharmacy & Pharmaceutical Sciences, Cardiff University, King Edward VII Avenue, Cardiff CF10 3NB, UK. Electronic address: simonsc@cardiff.ac.uk.

Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2019 Mar 15; Vol. 27 (6), pp. 1023-1033. Date of Electronic Publication: 2019 Feb 02.

Design and synthesis of novel 5-aminosalicylate (5-ASA)-4-thiazolinone hybrid derivatives with promising antiproliferative activity.

Autor: Abdu-Allah HH; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt. Electronic address: hagag.abdallah@pharm.au.edu.eg., Abdel-Moty SG; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt., El-Awady R; Cancer Biology Department, National Cancer Institute, Cairo University, Cairo, Egypt; Sharjah Institute for Medical Research and College of Pharmacy, University of Sharjah, Sharjah 27272, United Arab Emirates., El-Shorbagi AN; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt; Sharjah Institute for Medical Research and College of Pharmacy, University of Sharjah, Sharjah 27272, United Arab Emirates.

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2016 Apr 01; Vol. 26 (7), pp. 1647-50. Date of Electronic Publication: 2016 Feb 26.

Design, synthesis and molecular docking of some new 1,2,4-triazolobenzimidazol-3-yl acetohydrazide derivatives with anti-inflammatory-analgesic activities.

Autor: Mohammed AF; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut, 71526, Egypt., Abdel-Moty SG, Hussein MA, Abdel-Alim AA

Publikováno v: Archives of pharmacal research [Arch Pharm Res] 2013 Dec; Vol. 36 (12), pp. 1465-79. Date of Electronic Publication: 2013 May 28.