Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Abdel J. Njouendou"'
Autor:
Andrew A. Beng, Mathias E. Esum, Kebede Deribe, Abdel J. Njouendou, Patrick W. C. Ndongmo, Raphael A. Abong, Jerome Fru, Fanny F. Fombad, Gordon T. Nchanji, Glory Amambo, Narcisse T. V. Gandjui, Benjamin Biholong, Georges Nko’Ayissi, Patrick Mbia, Julie Akame, Peter I. Enyong, Steven D. Reid, Jean J. Tougoue, Yaobi Zhang, Samuel Wanji
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background The control of lymphatic filariasis (LF) caused by Wuchereria bancrofti in the Central African Region has been hampered by the presence of Loa loa due to severe adverse events that arise in the treatment with ivermectin. The immun
Externí odkaz:
https://doaj.org/article/e2053515b5e6472fae1cc6283954918c
Autor:
Valerine C. Chunda, Manuel Ritter, Ayukenchengamba Bate, Narcisse V. T. Gandjui, Mathias E. Esum, Fanny F. Fombad, Abdel J. Njouendou, Patrick W. C. Ndongmo, Mark J. Taylor, Achim Hoerauf, Laura E. Layland, Joseph D. Turner, Samuel Wanji
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-12 (2020)
Abstract Background Different immune mechanisms are capable of killing developmental stages of filarial nematodes and these mechanisms are also likely to vary between the primary and a challenge infection. However, the lack of a detailed analysis of
Externí odkaz:
https://doaj.org/article/a834dbf3f7084fdeaad7877732e1e6f2
Autor:
Samuel Wanji, Theobald Mue Nji, Louise Hamill, Laura Dean, Kim Ozano, Abdel J. Njouendou, Raphael A. Abong, Elisabeth Dibando Obie, Andrew Amuam, Relindis Ekanya, Winston Patrick Chounna Ndongmo, Bertrand L. Ndzeshang, Ebua Gallus Fung, Dum-Buo Nnamdi, Desmond Akumtoh Nkimbeng, Samuel Teghen, Emmanuel Kah, Helen Piotrowski, Armelle Forrer, Jahangir A. M. Khan, Maame E. Woode, Louis Niessen, Victoria Watson, Zakariaou Njoumemi, Michele E. Murdoch, Rachael Thomson, Sally Theobald, Peter Enyong, Joseph D. Turner, Mark J. Taylor
Publikováno v:
Parasites & Vectors, Vol 12, Iss 1, Pp 1-13 (2019)
Abstract Background Onchocerciasis is a priority neglected tropical disease targeted for elimination by 2025. The standard strategy to combat onchocerciasis is annual Community-Directed Treatment with ivermectin (CDTi). Yet, high prevalence rates and
Externí odkaz:
https://doaj.org/article/461a69575fce44e5b20bcada9f192621
Autor:
Nicolas P. Pionnier, Hanna Sjoberg, Valerine C. Chunda, Fanny F. Fombad, Patrick W. Chounna, Abdel J. Njouendou, Haelly M. Metuge, Bertrand L. Ndzeshang, Narcisse V. Gandjui, Desmond N. Akumtoh, Dizzle B. Tayong, Mark J. Taylor, Samuel Wanji, Joseph D. Turner
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Here, the authors develop a mouse model of Loa loa that reflects human infections, including eosinophilia, and determine effects of ivermectin treatment.
Externí odkaz:
https://doaj.org/article/a61c0d045a0e4834baada450b5e69d0f
Autor:
Abdel J. Njouendou, Fanny F. Fombad, Maeghan O’Neill, Denis Zofou, Chuck Nutting, Patrick C. Ndongmo, Arnaud J. Kengne-Ouafo, Timothy G. Geary, Charles D. Mackenzie, Samuel Wanji
Publikováno v:
Parasites & Vectors, Vol 11, Iss 1, Pp 1-11 (2018)
Abstract Background Co-infection with loiasis remains a potential problem in control programs targeting filarial infections. The effects of many anti-parasitic drugs often administered to Loa loa infected people are not well documented. This study co
Externí odkaz:
https://doaj.org/article/0d25ad1978ec4a70b3fc9724a894d751
Autor:
Laura Dean, Rachael Thomson, Kim Ozano, Sally Theobald, Armelle Forrer, Samuel Wanji, Elisabeth Dibando Obie, Theobald Mue Nji, Louise Hamill, Helen Piotrowski, Abdel J Njouendou, Relindis Ekanya, Winston Patrick Chounna Ndongmo, Ebua Gallus Fung, Dum-Buo Nnamdi, Raphael A Abong, Amuam Andrew Beng, Mathias Esum Eyong, Bertrand L Ndzeshang, Desmond Akumtoh Nkimbeng, Samuel Teghen, Anicetus Suireng, Ernerstine Ebot Ashu, Emmanuel Kah, Michele M Murdoch, Peter Enyong, Joseph D Turner, Mark J Taylor
Publikováno v:
BMJ Global Health, Vol 6, Iss 1 (2021)
Introduction Onchocerciasis is targeted for elimination mainly with annual community-directed treatment with ivermectin (CDTI). High infection levels have been reported in South-West Cameroon, despite ≥15 years of CDTI. The aim of this study was to
Externí odkaz:
https://doaj.org/article/11c2b86a7c264a7cb75b5b5f24429409
Autor:
Matthew, Chung, Jain, Aluvathingal, Robin E, Bromley, Suvarna, Nadendla, Fanny F, Fombad, Chi A, Kien, Narcisse V T, Gandjui, Abdel J, Njouendou, Manuel, Ritter, Lisa, Sadzewicz, Luke J, Tallon, Samuel, Wanji, Achim, Hoerauf, Kenneth, Pfarr, Julie C, Dunning Hotopp
Publikováno v:
Microbiology Resource Announcements
The 13,647-bp complete mitochondrial genome of Mansonella perstans was sequenced and is syntenic to the mitochondrial genome of Mansonella ozzardi. Phylogenetic analysis of the mitochondrial genome is consistent with the known phylogeny of ONC5 group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2e7666d0f460c8fd0c21f6b4b5d5c50
https://pubmed.ncbi.nlm.nih.gov/32703831
https://pubmed.ncbi.nlm.nih.gov/32703831
Autor:
Nicolas P, Pionnier, Hanna, Sjoberg, Valerine C, Chunda, Fanny F, Fombad, Patrick W, Chounna, Abdel J, Njouendou, Haelly M, Metuge, Bertrand L, Ndzeshang, Narcisse V, Gandjui, Desmond N, Akumtoh, Dizzle B, Tayong, Mark J, Taylor, Samuel, Wanji, Joseph D, Turner
Publikováno v:
Nature Communications
Elimination of the helminth disease, river blindness, remains challenging due to ivermectin treatment-associated adverse reactions in loiasis co-infected patients. Here, we address a deficit in preclinical research tools for filarial translational re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b6298bab9990aee376d0573b4526c87
https://pubmed.ncbi.nlm.nih.gov/30926803
https://pubmed.ncbi.nlm.nih.gov/30926803
Autor:
Mark J, Taylor, Thomas W, von Geldern, Louise, Ford, Marc P, Hübner, Kennan, Marsh, Kelly L, Johnston, Hanna T, Sjoberg, Sabine, Specht, Nicolas, Pionnier, Hayley E, Tyrer, Rachel H, Clare, Darren A N, Cook, Emma, Murphy, Andrew, Steven, John, Archer, Dominique, Bloemker, Franziska, Lenz, Marianne, Koschel, Alexandra, Ehrens, Haelly M, Metuge, Valerinne C, Chunda, Patrick W, Ndongmo Chounna, Abdel J, Njouendou, Fanny F, Fombad, Robert, Carr, Howard E, Morton, Ghaith, Aljayyoussi, Achim, Hoerauf, Samuel, Wanji, Dale J, Kempf, Joseph D, Turner, Stephen A, Ward
Publikováno v:
Science translational medicine. 11(483)
There is an urgent global need for a safe macrofilaricide drug to accelerate elimination of the neglected tropical diseases onchocerciasis and lymphatic filariasis. From an anti-infective compound library, the macrolide veterinary antibiotic, tylosin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fb5aec0eeb0a980ff0eb7b36977cb89d
https://pubmed.ncbi.nlm.nih.gov/30867321
https://pubmed.ncbi.nlm.nih.gov/30867321
Autor:
Hanna T, Sjoberg, Nicolas, Pionnier, Ghaith, Aljayyoussi, Haelly M, Metuge, Abdel J, Njouendou, Valerine C, Chunda, Fanny F, Fombad, Dizzle B, Tayong, Narcisse V T, Gandjui, Desmond N, Akumtoh, Patrick W N, Chounna, Bertrand L, Ndzeshang, Sophie, Lachaud, Fetene, Tekle, Ludo, Quirynen, Marc, Engelen, Benny, Baeten, Andrew, Steven, Stephen A, Ward, Mark J, Taylor, Samuel, Wanji, Joseph D, Turner
Publikováno v:
PLoS Neglected Tropical Diseases
The Onchocerca ochengi adult implant and Brugia malayi microfilariemic Severe-Combined Immunodeficient (SCID) mouse models are validated screens to measure macrofilaricidal and microfilaricidal activities of candidate onchocerciasis drugs. The purpos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7f216000d2a253ee5ee5c89024d3776d
https://pubmed.ncbi.nlm.nih.gov/30650071
https://pubmed.ncbi.nlm.nih.gov/30650071