Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Abdel Haleem M, Hussein"'
Autor:
Ahmed M. El-Saghier, Mohamed El-Naggar, Abdel Haleem M. Hussein, Abu-Bakr A. El-Adasy, M. Olish, Aboubakr H. Abdelmonsef
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
A new series of quinoline derivatives 5–12 were efficiently synthesized via one-pot multicomponent reaction (MCR) of resorcinol, aromatic aldehydes, β-ketoesters, and aliphatic/aromatic amines under solvent-free conditions. All products were obtai
Externí odkaz:
https://doaj.org/article/b67d77f333d44c719318ff1656c54672
Autor:
Abdel Haleem M. Hussein, Ahmed A. Khames, Abu-Bakr A. El-Adasy, Ahmed A. Atalla, Mohamed Abdel-Rady, Mohamed I. A. Hassan, Mahrous A. Abou-Salim, Yaseen A. M. M. Elshaier, Assem Barakat
Publikováno v:
Molecules, Vol 26, Iss 4, p 902 (2021)
The elaboration of new small molecules that target phosphodiesterase enzymes (PDEs), especially those of type 5 (PDE5), is an interesting and emerging topic nowadays. A new series of heterocycle-based aminothiazoles were designed and synthesized from
Externí odkaz:
https://doaj.org/article/0762ef94b998490a8d922f4b9b9bf0bf
Autor:
Abdel Haleem M. Hussein, Abu-Bakr A. El-Adasy, Ahmed M. El-Saghier, M. Olish, Aboubakr H. Abdelmonsef
Publikováno v:
RSC Advances. 12:12607-12621
Compounds 6a and 6b (with pyrimidine moiety, amide linkage, and phenolic substrate) might be potent bacterial flavohemoglobin (flavoHB) inhibitors and they could set a promising starting point for future design of antibacterial agents.
Autor:
Mahmoud H. Mahross, A. A. Atalla, Abdel Haleem M. Hussein, Ahmed Khames, Mohamed Abdel-Rady, Abu-Bakr A. A. M. El-Adasy
Publikováno v:
Synthetic Communications. 51:3099-3115
The arylhydrazones were treated with ethyl iodide, ethyl chloroacetate to afford the alkyl derivatives, which cyclized to the pyrazole derivatives, also, arylhydrazones were reacted with ethyl chlo...
Autor:
Abdel Haleem M, Hussein, Abu-Bakr A, El-Adasy, Ahmed M, El-Saghier, M, Olish, Aboubakr H, Abdelmonsef
Publikováno v:
RSC advances. 12(20)
Nitrogen-containing heterocycles have shown pharmacological properties against various diseases. Herein, in our study, flavoHB enzyme is a highly promising well-validated target for identification of antibacterial inhibitors using
Autor:
Mohamed T. M. Nemr, Abdel Haleem M. Hussein, Ahmed Khames, Mohamed Ibrahim Abu Hassan, A. A. Atalla, Mohamed Abdel-Rady, Abu-Bakr A. A. M. El-Adasy, Yaseen A. A. M. Elshaier
Publikováno v:
RSC Advances. 10:29723-29736
A new series of 2-aminothiazole derivatives was designed and prepared as phosphodiesterase type 5 (PDE5) regulators and COX-1/COX-2 inhibitors. The screening of the synthesized compounds for PDE5 activity was carried out using sildenafil as a referen
Publikováno v:
Synthetic Communications. 50:446-455
The arylhydrazones 3a, b were prepared and reacted with various reagents to yield the target compounds pyrazoles 6a–f, 1,6-dihydropyridazine-3-carboxamide derivatives 9a,b and thieno[3,4-d]pyridazi...
Autor:
Aboubakr Haredi Abdelmonsef, Abdel Haleem M. Hussein, Abu-Bakr A. A. M. El-Adasy, Ahmed M. M. El-Saghier, M. Olish, Mohamed El-Naggar
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
A new series of quinoline derivatives 5–12 were efficiently synthesized via one-pot multicomponent reaction (MCR) of resorcinol, aromatic aldehydes, β-ketoesters, and aliphatic/aromatic amines under solvent-free conditions. All products were obtai
Autor:
Mahrous A. Abou-Salim, Abdel Haleem M. Hussein, Yaseen A.M.M. Elshaier, Assem Barakat, Mohamed Abdel-Rady, Abu-Bakr A. A. M. El-Adasy, A. A. Atalla, Mohamed Ibrahim Abu Hassan, Ahmed Khames
Publikováno v:
Molecules, Vol 26, Iss 902, p 902 (2021)
Molecules
Volume 26
Issue 4
Molecules
Volume 26
Issue 4
The elaboration of new small molecules that target phosphodiesterase enzymes (PDEs), especially those of type 5 (PDE5), is an interesting and emerging topic nowadays. A new series of heterocycle-based aminothiazoles were designed and synthesized from
Autor:
Abdel Haleem M. Hussein, A. A. Atalla, Ahmed Khames, Mohamed Abdel-Rady, Abu-Bakr A. A. M. El-Adasy
Publikováno v:
ChemistrySelect. 2:1625-1629