Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Abdel A Alli"'
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165763 (2016)
Exosomes are nanometer-scale, cell-derived vesicles that contain various molecules including nucleic acids, proteins, and lipids. These vesicles can release their cargo into adjacent or distant cells and mediate intercellular communication and cellul
Externí odkaz:
https://doaj.org/article/e570f76549674cef87c9aada0687a6a6
Autor:
Xiaoqian eQian, Xuechen eLi, Titilayo O Ilori, Janet D. Klein, Rebecca P Hughey, Cong-jun eLi, Abdel A Alli, Zhengyu eGuo, Peng eYu, Xiang eSong, Guangping eChen
Publikováno v:
Frontiers in Physiology, Vol 6 (2015)
The UT-A1 urea transporter is crucial to the kidney’s ability to generate concentrated urine. Native UT-A1 from kidney inner medulla (IM) is a heavily glycosylated protein with two glycosylation forms of 97 and 117 kDa. In diabetes, UT-A1 protein a
Externí odkaz:
https://doaj.org/article/653c6cd45f3d4297b5fb33925d6fb5dc
Autor:
Bing-Chen eLiu, Xiao-Yu eLu, Xiang eSong, Ke-Yu eLei, Abdel A Alli, Hui-Fang eBao, Douglas C Eaton, He-Ping eMa
Publikováno v:
Frontiers in Physiology, Vol 3 (2013)
Scanning ion conductance microscope (SICM), which enables high-resolution imaging of cell surface topography, has been developed for over two decades. However, only recently, a unique scanning mode is increasingly used in biological studies to allow
Externí odkaz:
https://doaj.org/article/9b266a0103324b68aa13574f40a9e9b1
Autor:
Whitney C. Schramm, Niharika Bala, Tanmay Arekar, Zeeshan Malik, Kevin M. Chacko, Russell L. Lewis, Nancy D. Denslow, Yogesh Scindia, Abdel A. Alli
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 1038 (2024)
Cathepsin B (CtsB) is a ubiquitously expressed cysteine protease that plays important roles in health and disease. Urinary extracellular vesicles (uEVs) are released from cells associated with urinary organs. The antibiotic streptozotocin (STZ) is kn
Externí odkaz:
https://doaj.org/article/9b9464a245774e568d994ebb4daab8a3
Autor:
Raphaelle D. Vallera, Yanli Ding, Kimmo J. Hatanpaa, Justin A. Bishop, Sasan Mirfakhraee, Abdel A. Alli, Sergei G. Tevosian, Mouna Tabebi, Oliver Gimm, Peter Söderkvist, Cynthia Estrada-Zuniga, Patricia L. M. Dahia, Hans K. Ghayee
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Genetic testing has become the standard of care for many disease states. As a result, physicians treating patients who have tumors often rely on germline genetic testing results for making clinical decisions. Cases of two sisters carrying a germline
Externí odkaz:
https://doaj.org/article/0dd7056bb2134495ad2e44dcbc99498e
Autor:
Abdel A. Alli
Publikováno v:
Biology, Vol 12, Iss 8, p 1138 (2023)
Extracellular vesicles (EVs) include exosomes, microvesicles, and apoptotic bodies. EVs are released by all cell types and are found in biological fluids including plasma and urine. Urinary extracellular vesicles (uEVs) are a mixed population of EVs
Externí odkaz:
https://doaj.org/article/16dde938ccf24378a1b64687d21a703b
Autor:
Tamim Kawakibi, Niharika Bala, Lauren P. Liu, Louis A. Searcy, Nancy D. Denslow, Abdel A. Alli
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1489 (2023)
Cathpesin B is a multi-functional protease that plays numerous roles in physiology and pathophysiology. We hypothesized that actin cytoskeleton proteins that are substrates of cathepsin B, various lipids, and kinases that are regulated by lipids woul
Externí odkaz:
https://doaj.org/article/dbd96dc1e0234321a07b9a0d67f7c580
Autor:
Yogesh M. Scindia, Mohammed F. Gholam, Alina Waleed, Lauren P. Liu, Kevin M. Chacko, Dhruv Desai, Juliana Pena Lopez, Zeeshan Malik, Whitney C. Schramm, Angelica G. Morales, Morgan Carson-Marino, Abdel A. Alli
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 305 (2023)
Diabetic nephropathy is the primary cause of morbidity in type 2 diabetes mellitus (T2DM) patients. New data indicate that hypertension, a common comorbidity in T2DM, can worsen outcomes of diabetic nephropathy. While metformin is a commonly prescrib
Externí odkaz:
https://doaj.org/article/7fcb29cb8c8f465bab7cddaaa2531bef
Autor:
Carlos I. Lugo, Lauren P. Liu, Niharika Bala, Angelica G. Morales, Mohammed F. Gholam, Julia C. Abchee, Nasseem Elmoujahid, Ahmed Samir Elshikha, Rigena Avdiaj, Louis A. Searcy, Nancy D. Denslow, Sihong Song, Abdel A. Alli
Publikováno v:
Biomolecules, Vol 13, Iss 1, p 66 (2022)
Hypertension may develop before or after the onset of diabetes and it is known to increase the risk of developing diabetic nephropathy. Alpha-1 antitrypsin (AAT) is a multi-functional protein with beneficial effects in various diseases but its role i
Externí odkaz:
https://doaj.org/article/e33cb0622d164d038d065d98b67dae99
Autor:
Lauren P. Liu, Mohammed F. Gholam, Ahmed Samir Elshikha, Tamim Kawakibi, Nasseem Elmoujahid, Hassan H. Moussa, Sihong Song, Abdel A. Alli
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Human alpha-1 antitrypsin (hAAT) is a versatile protease inhibitor, but little is known about its targets in the aldosterone-sensitive distal nephron and its role in electrolyte balance and blood pressure control. We analyzed urinary electrolytes, os
Externí odkaz:
https://doaj.org/article/39214dccb6ec47b3a83591e25c088eb2