Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Abdeen Tunde, Ogunlana"'
Autor:
Elijah Kolawole Oladipo, Taiwo Ooreoluwa Ojo, Oluwabamise Emmanuel Elegbeleye, Olawale Quadri Bolaji, Moyosoluwa Precious Oyewole, Abdeen Tunde Ogunlana, Emmanuel Obanijesu Olalekan, Bamidele Abiodun, Daniel Adewole Adediran, Oluwaseun Adeola Obideyi, Seun Elijah Olufemi, Ahmad Mohammad Salamatullah, Mohammed Bourhia, Youssouf Ali Younous, Temitope Isaac Adelusi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-22 (2024)
Abstract The available Epstein Barr virus vaccine has tirelessly harnessed the gp350 glycoprotein as its target epitope, but the result has not been preventive. Right here, we designed a global multi-epitope vaccine for EBV; with special attention to
Externí odkaz:
https://doaj.org/article/e69e8844719e444b8aaea99542bf6c94
Autor:
Ibrahim Damilare Boyenle, Abdeen Tunde Ogunlana, Abdul-Quddus Kehinde Oyedele, Babatunde Kazeem Olokodana, Nurudeen Owolabi, Abdulmalik Salahudeen, Oluwafemi Timothy Aderenle, Taiwo Oluwafisayomi Oloyede, Temitope Isaac Adelusi, PhD
Publikováno v:
Journal of Taibah University Medical Sciences, Vol 18, Iss 3, Pp 461-469 (2023)
الملخص: أهداف البحث: في حين أن التوازن الدقيق في أفراد الأسرة المؤيدة للاستماتة والمضاد للاستماتة من عائلة بروتين الخلايا البائية 2 (بي سي
Externí odkaz:
https://doaj.org/article/e3080b9a970b4680892703113f379063
Autor:
Abdul-Quddus Kehinde Oyedele, Nurudeen Abiodun Owolabi, Tope Tunji Odunitan, Abosede Ajibare Christiana, Rukayat Olajumoke Jimoh, Waliu Olatunji Abdul Azeez, Maryam Bello-Hassan Titilayo, Abiola Sarah Soares, Adedayo Toluwani Adekola, Teslim Oluwaseyi Abdulkareem, Samson Olabode Oyelekan, Mojeed Ayoola Ashiru, Ibrahim Olajide Gbadebo, Habeebah Eyinade Olajumoke, Ibrahim Damilare Boyenle, Abdeen Tunde Ogunlana
Publikováno v:
Informatics in Medicine Unlocked, Vol 37, Iss , Pp 101170- (2023)
A prospective target for the therapy of solid tumors is KRAS G12D, the most prevalent oncogenic KRAS mutation. However, despite decades of research that focused on the identification of druggable compounds against this highly challenging therapeutic
Externí odkaz:
https://doaj.org/article/5d49b7965d9e448483893b2f7c5a0d6b
Autor:
Abdullahi Alausa, Ugwu Chukwuebuka Victor, Olumide Samuel Fadahunsi, Nurudeen Owolabi, Adeolu Adeniji, Mercy Olatinwo, Abdeen Tunde Ogunlana, Barakat Olaleke, Toheeb Adewale Balogun, Sunday Ogundepo, Peter Ifeoluwa Adegbola
Publikováno v:
Pharmacological Research, Vol 180, Iss , Pp 106242- (2022)
Cancer progression is enhanced through cell proliferation, with the crucial role of the transducer and transmembrane –signal regulator (GNG12) bringing it to the fore. Dysregulation of cancer cell metabolism, evasion of the immune system, cell cycl
Externí odkaz:
https://doaj.org/article/0c75818817d547529c97e9b75b2fc075
Autor:
Ibrahim Damilare Boyenle, Temitope Isaac Adelusi, Abdeen Tunde Ogunlana, Rofiat Adeyemi Oluwabusola, Najahtulahi Opeyemi Ibrahim, Ajao Tolulope, Ogundepo Sunday Okikiola, Bamigbade Lukman Adetunji, Ibraheem Omotayo Abioye, Abdul-Quddus Kehinde Oyedele
Publikováno v:
Informatics in Medicine Unlocked, Vol 28, Iss , Pp 100833- (2022)
Inhibition of Tumor Necrosis Factor-alpha (TNF-alpha) represents a therapeutic approach towards the management or treatment of various inflammatory diseases like rheumatoid arthritis and cancer, but the current treatment regimen against this target i
Externí odkaz:
https://doaj.org/article/da0af309582844658a1aa117ec526bce
Autor:
Temitope Isaac Adelusi, Abdul-Quddus Kehinde Oyedele, Ibrahim Damilare Boyenle, Abdeen Tunde Ogunlana, Rofiat Oluwabusola Adeyemi, Chiamaka Divine Ukachi, Mukhtar Oluwaseun Idris, Olamide Tosin Olaoba, Ibrahim Olaide Adedotun, Oladipo Elijah Kolawole, Yin Xiaoxing, Misbaudeen Abdul-Hammed
Publikováno v:
Informatics in Medicine Unlocked, Vol 29, Iss , Pp 100880- (2022)
With the financial requirements and high time associated with bringing a commercial drug to the market, the application of computer-aided drug design has been recognized as a powerful technology in the drug discovery pipeline. In accelerating drug di
Externí odkaz:
https://doaj.org/article/58a1ee4bc8044532a89d5e154830c3e7
Autor:
Abdeen Tunde Ogunlana, Abdul-Quddus Kehinde Oyedele, Ibrahim Damilare Boyenle, Sukurat Oluwatoyin Ayoola, Abosede Christiana Ajibare, Ayodeji Oluwadamilare Adeyemi, Lukmon Akanni Jinadu, Oluwafemi Timothy Adenrele, Abdullahi Opeyemi Alausa, Temitope Isaac Adelusi
Publikováno v:
Informatics in Medicine Unlocked, Vol 32, Iss , Pp 101032- (2022)
KRAS is one of the most investigated anticancer targets today, owing to its common mutations in a variety of lethal malignancies. KRAS G12C has been the focus of cancer research since the identification of the druggable allosteric binding site locate
Externí odkaz:
https://doaj.org/article/20d7cf75670344c38d0ee97df9ca565e
Autor:
Abdullahi Alausa, Ugwu Chukwuebuka Victor, Ugwu Obiora Celestine, Ismail Abiodun Eweje, Toheeb Adewale Balogun, Rofiat Adeyemi, Mercy Olatinwo, Abdeen Tunde Ogunlana, Oladapo Oladipo, Barakat Olaleke
Publikováno v:
Phytomedicine Plus, Vol 1, Iss 4, Pp 100133- (2021)
Background: The resurgence of interest in the metabolic regulator sestrin 2 (SESN2) has played a pivotal role in the several biochemical and immunological roles ascribed to it. Structural analysis of this highly conserved GTPase- activating protein c
Externí odkaz:
https://doaj.org/article/97fd38de3b5a4dacb022db4e86f87757
Autor:
Abdul-Quddus Kehinde, Oyedele, Abdeen Tunde, Ogunlana, Ibrahim Damilare, Boyenle, Ayodeji Oluwadamilare, Adeyemi, Temionu Oluwakemi, Rita, Temitope Isaac, Adelusi, Misbaudeen, Abdul-Hammed, Oluwabamise Emmanuel, Elegbeleye, Tope Tunji, Odunitan
Publikováno v:
Molecular Diversity.
The continuous approval of covalent drugs in recent years for the treatment of diseases has led to an increased search for covalent agents by medicinal chemists and computational scientists worldwide. In the computational parlance, molecular docking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e91494aace2467605e9e010edc6de7f
https://doi.org/10.1007/s11030-022-10523-4
https://doi.org/10.1007/s11030-022-10523-4
Autor:
Abdul-Quddus Kehinde, Oyedele, Temitope Isaac, Adelusi, Abdeen Tunde, Ogunlana, Rofiat Oluwabusola, Adeyemi, Opeyemi Emmanuel, Atanda, Musa Oladayo, Babalola, Mojeed Ayoola, Ashiru, Isong Josiah, Ayoola, Ibrahim Damilare, Boyenle
Publikováno v:
Journal of Molecular Modeling. 28
In the vast majority of malignancies, the p53 tumor suppressor pathway is compromised. In some cancer cells, high levels of MDM2 polyubiquitinate p53 and mark it for destruction, thereby leading to a corresponding downregulation of the protein. MDM2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b55f6ef2591b0b39c7b0deab7a7da2
https://doi.org/10.1007/s00894-022-05131-w
https://doi.org/10.1007/s00894-022-05131-w