Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Abdallah M. Eteleeb"'
Autor:
Abdallah M. Eteleeb, Prasanth K. Thunuguntla, Kyla Z. Gelev, Cynthia Y. Tang, Emily B. Rozycki, Alexander Miller, Jonathan T. Lei, Reyka G. Jayasinghe, Ha X. Dang, Nicole M. White, Jorge S. Reis-Filho, Elaine R. Mardis, Matthew J. Ellis, Li Ding, Jessica M. Silva-Fisher, Christopher A. Maher
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-12 (2022)
Abstract Late-stage relapse (LSR) in patients with breast cancer (BC) occurs more than five years and up to 10 years after initial treatment and has less than 30% 5-year relative survival rate. Long non-coding RNAs (lncRNAs) play important roles in B
Externí odkaz:
https://doaj.org/article/06f93b9f73504e1787c7cc91e8e64b0c
Autor:
Miguel A. Minaya, Sidhartha Mahali, Abhirami K. Iyer, Abdallah M. Eteleeb, Rita Martinez, Guangming Huang, John Budde, Sally Temple, Alissa L. Nana, William W. Seeley, Salvatore Spina, Lea T. Grinberg, Oscar Harari, Celeste M. Karch
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Introduction: More than 50 mutations in the MAPT gene result in heterogeneous forms of frontotemporal lobar dementia with tau inclusions (FTLD-Tau). However, early pathogenic events that lead to disease and the degree to which they are common across
Externí odkaz:
https://doaj.org/article/5c8300a5cf374c2ba727c09cab44b1dd
Autor:
Fuhai Li, Abdallah M. Eteleeb, William Buchser, Christopher Sohn, Guoqiao Wang, Chengjie Xiong, Philip R. Payne, Eric McDade, Celeste M. Karch, Oscar Harari, Carlos Cruchaga
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
ObjectivesNeuroinflammation signaling has been identified as an important hallmark of Alzheimer’s disease (AD) in addition to amyloid β plaques (Aβ) and neurofibrillary tangles (NFTs). However, the molecular mechanisms and biological processes of
Externí odkaz:
https://doaj.org/article/d25cd95224e3452fb0e5ec8b43c5c39c
Autor:
Abdallah M. Eteleeb, David A. Quigley, Shuang G. Zhao, Duy Pham, Rendong Yang, Scott M. Dehm, Jingqin Luo, Felix Y. Feng, Ha X. Dang, Christopher A. Maher
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Whole genome sequencing (WGS) has enabled the discovery of genomic structural variants (SVs), including those targeting intergenic and intronic non-coding regions that eluded previous exome focused strategies. However, the field currently la
Externí odkaz:
https://doaj.org/article/028d671856044b26a0873e62b77eaea6
Autor:
Jin Zhang, Abdallah M. Eteleeb, Emily B. Rozycki, Matthew J. Inkman, Amy Ly, Russell E. Scharf, Kay Jayachandran, Bradley A. Krasnick, Thomas Mazur, Nicole M. White, Ryan C. Fields, Christopher A. Maher
Publikováno v:
Non-Coding RNA, Vol 8, Iss 1, p 9 (2022)
Existing small noncoding RNA analysis tools are optimized for processing short sequencing reads (17–35 nucleotides) to monitor microRNA expression. However, these strategies under-represent many biologically relevant classes of small noncoding RNAs
Externí odkaz:
https://doaj.org/article/100a22e5cc4946f5a96d6c99f3219cb5
Autor:
Abdallah M Eteleeb, Brenna C Novotny, Carolina Soriano Tarraga, Christopher Sohn, Eliza Dhungel, Logan Brase, Aasritha Nallapu, Jared Buss, Fabiana Farias, Kristy Bergmann, Joseph Bradley, Joanne Norton, Jen Gentsch, Fengxian Wang, Albert A Davis, John C Morris, Celeste M Karch, Richard J Perrin, Bruno A Benitez, Oscar Harari
Publikováno v:
PLoS Biology, Vol 22, Iss 4, p e3002607 (2024)
Unbiased data-driven omic approaches are revealing the molecular heterogeneity of Alzheimer disease. Here, we used machine learning approaches to integrate high-throughput transcriptomic, proteomic, metabolomic, and lipidomic profiles with clinical a
Externí odkaz:
https://doaj.org/article/c71d7c799edd465daeb99f4beb049d3a
Autor:
Abdallah M. Eteleeb, Brenna C. Novotny, Carolina Soriano Tarraga, Christopher Sohn, Eliza Dhungel, Logan Brase, Aasritha Nallapu, Jared Buss, Fabiana Farias, Kristy Bergmann, Joanne Norton, Jen Gentsch, Fengxian Wang, Albert A. Davis, John C. Morris, Celeste M. Karch, Richard J. Perrin, Bruno A. Benitez, Oscar Harari
Clinical and molecular heterogeneity of Alzheimer disease (AD) is increasingly recognized as a major factor impacting the diagnosis, the design of therapeutic interventions and clinical trials, and therefore possibly delaying the development of effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03c602be98094cb8f31c4424598d8f44
https://doi.org/10.1101/2022.12.10.22283295
https://doi.org/10.1101/2022.12.10.22283295
Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer's disease brains
Autor:
Brenna C, Novotny, Maria Victoria, Fernandez, Ciyang, Wang, John P, Budde, Kristy, Bergmann, Abdallah M, Eteleeb, Joseph, Bradley, Carol, Webster, Curtis, Ebl, Joanne, Norton, Jen, Gentsch, Umber, Dube, Fengxian, Wang, John C, Morris, Randall J, Bateman, Richard J, Perrin, Eric, McDade, Chengjie, Xiong, Jasmeer, Chhatwal, Alison, Goate, Martin, Farlow, Peter, Schofield, Helena, Chui, Celeste M, Karch, Carlos, Cruchaga, Bruno A, Benitez, Oscar, Harari
Publikováno v:
Alzheimer'sdementia : the journal of the Alzheimer's AssociationREFERENCES.
The identification of multiple genetic risk factors for Alzheimer's disease (AD) suggests that many pathways contribute to AD onset and progression. However, the metabolomic and lipidomic profiles in carriers of distinct genetic risk factors are not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::df6b6dc821b45ba7b4f48b67266a6e0f
https://pubmed.ncbi.nlm.nih.gov/36251323
https://pubmed.ncbi.nlm.nih.gov/36251323
Autor:
Miguel A. Minaya, Sidhartha Mahali, Abhirami K. Iyer, Rita Martinez, John Budde, Sally Temple, Abdallah M. Eteleeb, Carlos Cruchaga, Oscar Harari, Celeste M. Karch
More than 50 mutations in the MAPT gene result in heterogeneous forms of frontotemporal lobar dementia with tau inclusions (FTLD-tau). However, early pathogenic events that lead to disease and the degree to which they are common across MAPT mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef8c07948a7cec878f2ffe82b25c7f6f
https://doi.org/10.1101/2022.06.10.22276260
https://doi.org/10.1101/2022.06.10.22276260
Autor:
Duy Pham, Ha X. Dang, Abdallah M. Eteleeb, Christopher G. Maher, Felix Y. Feng, Scott M. Dehm, Jingqin Luo, Shuang G. Zhao, Rendong Yang, David A. Quigley
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Whole genome sequencing (WGS) has enabled the discovery of genomic structural variants (SVs), including those targeting intergenic and intronic non-coding regions that eluded previous exome focused strategies. However, the field currently lacks an au
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9c05fa2bd5a6a089e1a57f7ab308640
https://doaj.org/article/028d671856044b26a0873e62b77eaea6
https://doaj.org/article/028d671856044b26a0873e62b77eaea6