Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Abdallah Ezzitouni"'
Publikováno v:
Organic Process Research & Development. 13:581-583
A simple, inexpensive, one-step general procedure was developed for the preparation of medium-chain fatty acid (MCFA) metal salts. This approach offers the advantage of a practical route and is superior to literature methods. Also, it overcomes many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bf295dc7a7c81266af4f3f5666c47e0
https://doi.org/10.1021/op900038v
https://doi.org/10.1021/op900038v
Autor:
Clifford George, Joseph J. Barchi, Victor E. Marquez, Maqbool A. Siddiqui, Ron J. Feldman, Pamela Russ, Abdallah Ezzitouni, Hiroaki Mitsuya, Harry Ford
Publikováno v:
Nucleosides and Nucleotides. 17:1881-1884
Two conformationally locked carba-AZT nucleoside 5′-triphosphates built on a rigid bicyclo[3.1.0]hexane template showed exclusive Northern (2E) and Southern (3E) conformations, respectively. Inhibition of reverse transcriptase (RT) occurred selecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a1ef6f36a165d7c20cf581b8feffc10
https://doi.org/10.1080/07328319808004726
https://doi.org/10.1080/07328319808004726
Autor:
Victor E. Marquez, Clifford George, Hiroaki Mitsuya, Abdallah Ezzitouni, Harry Ford, Pamela Russ, Ron J. Feldman, Joseph J. Barchi, Maqbool A. Siddiqui
Publikováno v:
Journal of the American Chemical Society. 120:2780-2789
It has been proposed that the preference of 3‘-azido-3‘-deoxythymidine (AZT) for the extreme 3E (south) conformation, as observed in its X-ray structure, is responsible for its potent anti-HIV acti...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf120f844146de4173fe2d38113e9da3
https://doi.org/10.1021/ja973535+
https://doi.org/10.1021/ja973535+
Publikováno v:
The Journal of Organic Chemistry. 62:4870-4873
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aee57ab81e6c057cbbfeab164d365308
https://doi.org/10.1021/jo962124t
https://doi.org/10.1021/jo962124t
Autor:
Clifford George, Victor E. Marquez, Maqbool A. Siddiqui, Pamela Russ, Abdallah Ezzitouni, Hisafumi Ikeda
Publikováno v:
Nucleosides and Nucleotides. 16:1431-1434
A conformational analysis of carbocyclic nucleosides built on a rigid bicyclo[3.1.0]hexane template (1–4, Northern and 5–8 Southern) showed that the Northern conformation prefers an anti glycosyl torsion angle whereas the Southern conformation fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d241528e0d6d0039b44f58def0dd1087
https://doi.org/10.1080/07328319708006199
https://doi.org/10.1080/07328319708006199
Publikováno v:
Tetrahedron Letters. 38:723-726
In a functionalized cyclopentene having allylic OH and NH-acyl groups on opposite faces of the ring, the diastereoselective delivery of the incoming methylene group in the diethylzinc version of the Simmons-Smith reaction was completely directed by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f33429246233b8d6301007ce36d94789
https://doi.org/10.1016/s0040-4039(96)02425-2
https://doi.org/10.1016/s0040-4039(96)02425-2
Autor:
Victor E. Marquez, Abdallah Ezzitouni
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :1073-1078
The construction of carbocyclic nucleosides with a fixed 3E ring pucker in the Southern hemisphere of the pseudorotational cycle is achieved from a common precursor carbocyclic amine, (1S,3S,4R,5 S )-3-benzyloxy-4-benzyloxymethyl-1-aminobicyclo[3.1.0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0cf37a9285c287d282f7ee2052e2bd6
https://doi.org/10.1039/a604352f
https://doi.org/10.1039/a604352f
Autor:
Victor E. Marquez, Pamela Russ, Abdallah Ezzitouni, Maqbool A. Siddiqui, Mark D. Matteucci, Richard W. Wagner, Jianying Wang
Publikováno v:
Journal of Medicinal Chemistry. 39:3739-3747
The sugar moiety of nucleosides in solution is known to exist in a rapid dynamic equilibrium between extreme Northern and Southern conformations as defined in the pseudorotational cycle. In the present work, we describe how the bicyclo[3.1.0]hexane t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::227cade56782c3ae30bd1ada60ab3509
https://doi.org/10.1021/jm960306+
https://doi.org/10.1021/jm960306+
Publikováno v:
Tetrahedron Letters. 34:315-318
Three 2′, 3′-unsaturated pyrimidine nucleosides, bearing an azido-methyl group at 2′ or 3′ were synthesized as potential anti-HIV agents. The key step involves an SN2′ opening of 2, 2′ or 2, 3′-anhydronucleosides by azide ion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67b247c2befce621e7b78b704568d5f7
https://doi.org/10.1016/s0040-4039(00)60576-2
https://doi.org/10.1016/s0040-4039(00)60576-2
Publikováno v:
ChemInform. 22
Starting from 1,2-O-isopropylidene-α-D-xylofuranose, a versatile method for the synthesis of branched 3'-deoxy-2',3'-didehydro nucleosides is described and exemplified for an analogue of 3'-deoxy-2',3'-didehydrothymidine (d4T)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5a7480f1cf07a2335b9a08d9d7c9aca
https://doi.org/10.1002/chin.199101344
https://doi.org/10.1002/chin.199101344