Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Abdallah E Abdallah"'
Autor:
Abdallah E. Abdallah, Reda R. Mabrouk, Maged Mohammed Saleh Al Ward, Sally I. Eissa, Eslam B. Elkaeed, Ahmed B. M. Mehany, Mariam A. Abo-Saif, Ola A. El-Feky, Mohamed S. Alesawy, Mohamed Ayman El-Zahabi
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 573-591 (2022)
Based on quinazoline, quinoxaline, and nitrobenzene scaffolds and on pharmacophoric features of VEGFR-2 inhibitors, 17 novel compounds were designed and synthesised. VEGFR-2 IC50 values ranged from 60.00 to 123.85 nM for the new derivatives compared
Externí odkaz:
https://doaj.org/article/3af1c5c676984e4bb4c5c70fd837b96c
Autor:
Nadia T. A. Dawoud, Esmail M. El-Fakharany, Abdallah E. Abdallah, Hamada El-Gendi, Doaa R. Lotfy
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract The current study was directed toward developing a new series of fused heterocycles incorporating indazolylthiazole moiety. The newly synthesized compounds were characterized through elemental analysis and spectral data (IR, 1H-NMR, 13C-NMR,
Externí odkaz:
https://doaj.org/article/78c7a8426fcd42a9862b54bd9aff388e
Autor:
Alaa Elwan, Abdallah E. Abdallah, Hazem A. Mahdy, Mohammed A. Dahab, Mohammed S. Taghour, Eslam B. Elkaeed, Ahmed B. M. Mehany, Ahmed Nabeeh, Mohammed Adel, Aisha A. Alsfouk, Hazem Elkady, Ibrahim H. Eissa
Publikováno v:
Molecules, Vol 27, Iss 15, p 5047 (2022)
This work is one of our efforts to discover potent anticancer agents. We modified the most promising derivative of our previous work concerned with the development of VEGFR-2 inhibitor candidates. Thirteen new compounds based on benzoxazole moiety we
Externí odkaz:
https://doaj.org/article/9b88464c4c084ba2bfee7e48638f798d
Autor:
Anas Ramadan Kotb, Abdallah E. Abdallah, Hazem Elkady, Ibrahim H. Eissa, Mohammed S. Taghour, Dina Abed Bakhotmah, Tamer M. Abdelghany, Mohamed Ayman El-Zahabi
Publikováno v:
RSC Advances. 13:10488-10502
Novel thalidomide analogs as anticancer immunomodulatory agents.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0802a2906d6b9ca53d827e7eaf4b6dd3
https://doi.org/10.1039/d3ra00066d
https://doi.org/10.1039/d3ra00066d
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1595 (2021)
Tungsten oxide WO3 nanoparticles (NPs) were prepared in a form of nanosheets with homogeneous size and dimensions in one step through acid precipitation using a cation exchange column. The resulting WO3 nanosheet surface was decorated with one of the
Externí odkaz:
https://doaj.org/article/322e410c7ac541f4a43c1dd1ca0330fb
As an extension to our previous work for the development of new thalidomide analogs, the current work offers new insights into the immunomodulatory and anticancer activities of quinazolinone based molecules carrying a glutarimide moiety. The findings
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4daf4dbb8604acf58cb971dc8621b448
https://doi.org/10.21203/rs.3.rs-2916749/v1
https://doi.org/10.21203/rs.3.rs-2916749/v1
Autor:
Mohamed S. Alesawy, Abdallah E. Abdallah, Mohammed S. Taghour, Eslam B. Elkaeed, Ibrahim H. Eissa, Ahmed M. Metwaly
Publikováno v:
Molecules, Vol 26, Iss 9, p 2806 (2021)
The Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused the “COVID-19” disease that has been declared by WHO as a global emergency. The pandemic, which emerged in China and widespread all over the world, has no specific treatment
Externí odkaz:
https://doaj.org/article/57f77933f88c405aaa1f855696f585dd
Autor:
Anas Ramadan Kotb, Dina A. Bakhotmah, Abdallah E. Abdallah, Hazem Elkady, Mohammed S. Taghour, Ibrahim. H. Eissa, Mohamed Ayman El-Zahabi
Publikováno v:
RSC advances. 12(52)
Cancer is still a dangerous disease with a high mortality rate all over the world. In our attempt to develop potential anticancer candidates, new quinazoline and phthalazine based compounds were designed and synthesized. The new derivatives were buil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::091fbb1d4c933809382eed0ad3a5c9c1
https://pubmed.ncbi.nlm.nih.gov/36505721
https://pubmed.ncbi.nlm.nih.gov/36505721
Autor:
Abdallah E. Abdallah, Ibrahim H. Eissa, Ahmed B.M. Mehany, Helmy Sakr, Ahmed Atwa, Khaled El-Adl, Mohamed Ayman El-Zahabi
Publikováno v:
Journal of Molecular Structure. 1281:135164
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb0201dfccf53a32b715431b897fb326
https://doi.org/10.1016/j.molstruc.2023.135164
https://doi.org/10.1016/j.molstruc.2023.135164
Autor:
Esmail M. El-Fakharany, Mohamed H. Kalaba, Abdallah E. Abdallah, Hazem Elkady, Noura M. Abo Shama, Mohamed H. Sharaf, Ahmed Mostafa, Sally I. Eissa, Sara H. Mahmoud, Ahmed A. Al-Karmalawy, Mohamed S Alesawy
Publikováno v:
New Journal of Chemistry. 45:16557-16571
Regarding the crucial role of deubiquitinase (DUB) enzymes in many viruses, in particular, Adenovirus, HSV-1, coxsackievirus, and SARS-CoV-2, DUB inhibition was reported as an effective new approach to find new effective antiviral agents. In the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a40b4f2c343ef55369f93d0f8046a0f5
https://doi.org/10.1039/d1nj02710g
https://doi.org/10.1039/d1nj02710g