Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Abdallah Abu Taha"'
Autor:
Matteo Malinverno, Claudio Maderna, Abdallah Abu Taha, Monica Corada, Fabrizio Orsenigo, Mariaelena Valentino, Federica Pisati, Carmela Fusco, Paolo Graziano, Monica Giannotta, Qing Cissy Yu, Yi Arial Zeng, Maria Grazia Lampugnani, Peetra U. Magnusson, Elisabetta Dejana
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Cerebral cavernous malformation is a vascular disease characterized by capillary-venous cavernomas in the central nervous system. Here the authors show that cavernomas display benign tumor characteristics and originate from the clonal expansion of mu
Externí odkaz:
https://doaj.org/article/697db73cfa424b9ba46d1f4d22882162
Autor:
Fabrizio Orsenigo, Maria Grazia Lampugnani, Matteo Malinverno, Federica Pisati, Abdallah Abu Taha, Peetra U. Magnusson, Monica Corada, Monica Giannotta, Yi Arial Zeng, Claudio Maderna, Carmela Fusco, Mariaelena Valentino, Qing Cissy Yu, Paolo Graziano, Elisabetta Dejana
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications
Nature Communications
Cerebral cavernous malformation (CCM) is a neurovascular familial or sporadic disease that is characterised by capillary-venous cavernomas, and is due to loss-of-function mutations to any one of three CCM genes. Familial CCM follows a two-hit mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387343385e9eba07c1efcbc09f63d3e2
http://link.springer.com/article/10.1038/s41467-019-10707-x
http://link.springer.com/article/10.1038/s41467-019-10707-x
Autor:
Stefan Zahler, Holger Gerhardt, Julian Kirsch, Ulrich Pohl, Abdallah Abu Taha, Alessia Fraccaroli, Eloi Montanez, Jochen Seebach, Hans-J. Schnittler, Stephan Huveneers, Ricardo P. Casaroli-Marano, Bettina Pitter
Publikováno v:
Circulation research, 117(1), 29-40. Lippincott Williams and Wilkins
Circulation Research
Circulation Research
Supplemental Digital Content is available in the text.
Rationale: Angiogenesis and vessel integrity depend on the adhesion of endothelial cells (ECs) to the extracellular matrix and to adjacent ECs. The focal adhesion protein α-parvin (α-pv) i
Rationale: Angiogenesis and vessel integrity depend on the adhesion of endothelial cells (ECs) to the extracellular matrix and to adjacent ECs. The focal adhesion protein α-parvin (α-pv) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e6700ddcc5a27a140df17e6bf6be8c
https://doi.org/10.1161/circresaha.117.305818
https://doi.org/10.1161/circresaha.117.305818
Publikováno v:
Molecular Biology of the Cell
The ARP2/3 complex controls junction-associated intermittent lamellipodia (JAIL), which trigger VE-cadherin adhesion and dynamics. JAIL formation maintains paraendothelial barrier function under physiological conditions and depends on the local VE-ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4d9ce8d7ce836996e0b76e9c6a0c8d9
https://doi.org/10.1091/mbc.e13-07-0404
https://doi.org/10.1091/mbc.e13-07-0404
Autor:
Nico Lindemann, Xiaoyi Jiang, Sven Bogdan, Hans-Joachim Schnittler, Klaus Brinkmann, Abdallah Abu Taha, Janine Lenk, Jochen Seebach
Publikováno v:
Histochemistry and cell biology. 144(6)
Endothelial junctions are dynamic structures organized by multi-protein complexes that control monolayer integrity, homeostasis, inflammation, cell migration and angiogenesis. Newly developed methods for both the genetic manipulation of endothelium a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d919fa11183792c49920b633fa6372b
https://pubmed.ncbi.nlm.nih.gov/26275669
https://pubmed.ncbi.nlm.nih.gov/26275669
Autor:
Abdallah Abu Taha, Hans-J. Schnittler
Publikováno v:
Cell adhesionmigration. 8(2)
Endothelial adherens junctions are critical for physiological and pathological processes such as differentiation, maintenance of entire monolayer integrity, and the remodeling. The endothelial-specific VE-cadherin/catenin complex provides the backbon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d7a762dddaf2add53ac98bcd1669f1
https://pubmed.ncbi.nlm.nih.gov/24621569
https://pubmed.ncbi.nlm.nih.gov/24621569
Autor:
Nico Lindemann, Jochen Seebach, Abdallah Abu Taha, Maria Odenthal Schnittler, Hans Schnittler, Muna Taha
Publikováno v:
Cell and tissue research. 355(3)
The vascular endothelium is a cellular interface between the blood and the interstitial space of tissue, which controls the exchange of fluid, solutes and cells by both transcellular and paracellular means. To accomplish the demands on barrier functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049dbf6081e91d6706be9e35016a5d63
https://pubmed.ncbi.nlm.nih.gov/24643678
https://pubmed.ncbi.nlm.nih.gov/24643678
Autor:
Romy Kronstein, Hans-Joachim Schnittler, Carsten Minten, Abdallah Abu Taha, Yvan Arsenijevic, Tatiana Afanasieva, Marek Drab, Jochen Seebach, Stefan Liebner, Sylvia Grossklaus, Britta Engelhardt
Publikováno v:
Cardiovascular Research, vol. 93, no. 1, pp. 130-140
Kronstein, Romy; Seebach, Jochen; Grossklaus, Sylvia; Minten, Carsten; Engelhardt, Britta; Drab, Marek; Liebner, Stefan; Arsenijevic, Yvan; Taha, Abdallah Abu; Afanasieva, Tatiana; Schnittler, Hans-Joachim (2012). Caveolin-1 opens endothelial cell junctions by targeting catenins. Cardiovascular research, 93(1), pp. 130-40. Oxford: Oxford University Press 10.1093/cvr/cvr256
Kronstein, Romy; Seebach, Jochen; Grossklaus, Sylvia; Minten, Carsten; Engelhardt, Britta; Drab, Marek; Liebner, Stefan; Arsenijevic, Yvan; Taha, Abdallah Abu; Afanasieva, Tatiana; Schnittler, Hans-Joachim (2012). Caveolin-1 opens endothelial cell junctions by targeting catenins. Cardiovascular research, 93(1), pp. 130-40. Oxford: Oxford University Press 10.1093/cvr/cvr256
AIMS: A fundamental phenomenon in inflammation is the loss of endothelial barrier function, in which the opening of endothelial cell junctions plays a central role. However, the molecular mechanisms that ultimately open the cell junctions are largely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5659795732fad4950547b7c085aac6be
https://serval.unil.ch/notice/serval:BIB_CCF339084AD6
https://serval.unil.ch/notice/serval:BIB_CCF339084AD6
CDC42 Deletion Elicits Cerebral Vascular Malformations via Increased MEKK3-Dependent KLF4 Expression
Autor:
Marco Castro, Bàrbara Laviña, Christer Betsholtz, Cord Brakebusch, Konstantin Gaengel, Koji Ando, Abdallah Abu Taha, Elisabetta Dejana, Alberto Álvarez-Aznar
Publikováno v:
Circulation Research
Rationale: Aberrant formation of blood vessels precedes a broad spectrum of vascular complications; however, the cellular and molecular events governing vascular malformations are not yet fully understood. Objective: Here, we investigated the role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e150115966b1add2a61e280de384dd