Exploring new cyclohexane carboxamides based GABA agonist: Design, synthesis, biological evaluation, in silico ADME and docking studies.

Autor: Hamada Abd-Allah W; Pharmaceutical Chemistry Department, Collage of Pharmaceutical Science and Drug Manufacturing, Misr University for Science and Technology, P.O. 77, 6th of October City, Giza, Egypt. Electronic address: Walaa.abdalla@must.edu.eg., Abd El-Mohsen Anwar M; Pharmaceutical Chemistry Department, Collage of Pharmaceutical Science and Drug Manufacturing, Misr University for Science and Technology, P.O. 77, 6th of October City, Giza, Egypt., Mohammed ER; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, 11562 Cairo, Egypt., Elbaset MA; Department of Pharmacology, Medical Research and Clinical Studies Institute, National Research Centre, Giza, Egypt., El Moghazy SM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, 11562 Cairo, Egypt.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2023 Jul; Vol. 136, pp. 106561. Date of Electronic Publication: 2023 Apr 25.