Zobrazeno 1 - 10
of 7 675
pro vyhledávání: '"Abca1"'
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract Ischemic stroke (IS) is a severe cerebrovascular disease with high disability and mortality rates, where the inflammatory response is crucial to its progression and prognosis. Efferocytosis, the prompt removal of dead cells, can reduce exces
Externí odkaz:
https://doaj.org/article/769d6931c6be404c9c5c9f9dd43d1d1d
Publikováno v:
BioTechniques, Vol 76, Iss 8, Pp 405-410 (2024)
Adipocyte characterization and assessing membrane proteins using flow cytometry has been proven to be challenging as adipocytes are fragile, especially in subjects with high BMI. We overcame these challenges through a protocol optimizing tissue diges
Externí odkaz:
https://doaj.org/article/5d8e70bd934946f183ff529f878d0721
Autor:
Ting-Chun Lin, Chun-Yao Huang, Yu-Ling Li, Hung-Yi Chiou, Chaur-Jong Hu, Jiann-Shing Jeng, Sung-Chun Tang, Lung Chan, Li-Ming Lien, Huey-Juan Lin, Chu-Chien Lin, Yi-Chen Hsieh
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-10 (2024)
Abstract Despite recent findings indicating a paradoxical association between high-density lipoprotein cholesterol (HDL-C) levels and cardiovascular disease (CVD) mortality, the impact of HDL-C on subsequent outcomes after ischemic stroke remains unc
Externí odkaz:
https://doaj.org/article/528e813c64784412a95a428103a7bef5
Autor:
Muhlis Akman, Ciro Monteleone, Gabriella Doronzo, Martina Godel, Francesca Napoli, Alessandra Merlini, Virginia Campani, Valeria Nele, Elisa Balmas, Tatiana Chontorotzea, Simona Fontana, Sabrina Digiovanni, Francesca Alice Barbu, Elena Astanina, Niloufar Jafari, Iris Chiara Salaroglio, Joanna Kopecka, Giuseppe De Rosa, Thomas Mohr, Alessandro Bertero, Luisella Righi, Silvia Novello, Giorgio Vittorio Scagliotti, Federico Bussolino, Chiara Riganti
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-23 (2024)
Abstract Background In non-small cell lung cancer (NSCLC) the efficacy of chemo-immunotherapy is affected by the high expression of drug efflux transporters as ABCC1 and by the low expression of ABCA1, mediating the isopentenyl pyrophosphate (IPP)-de
Externí odkaz:
https://doaj.org/article/4a6851a8a8824044acb7cc89ddb408bf
Publikováno v:
Redox Experimental Medicine, Vol 2024, Iss 1, Pp 1-8 (2024)
Objective: We tested the effect of 27-hydroxycholesterol (27OHC) on the expression and synthesis of two membrane transporters involved in sterols extrusion from the intestinal epithelium into the gut lumen: ATP-binding cassette A1 (ABCA1) and G8 (ABC
Externí odkaz:
https://doaj.org/article/7d8b854bdc9c42b8b4ec255345fd2b62
Autor:
Zhilin Ou, Yongquan Cheng, Hao Ma, Kai Chen, Qiong Lin, Jiayu Chen, Ruqin Guo, Zhiping Huang, Qixian Cheng, Nima Alaeiilkhchi, Qingan Zhu, Zucheng Huang, Hui Jiang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Background Spinal cord injury (SCI) is characterized by extensive demyelination and inflammatory responses. Facilitating the clearance of lipid droplets (LDs) within microglia contributes to creating a microenvironment that favors neural rec
Externí odkaz:
https://doaj.org/article/1ccc7e99bc21401fa5c0b94cd36c8729
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The inflammatory corpuscle recombinant absents in melanoma 2 (AIM2) and cholesterol efflux protein ATP binding cassette transporter A1(ABCA1) have been reported to play opposing roles in atherosclerosis (AS) plaques. However, the relationshi
Externí odkaz:
https://doaj.org/article/acb1afe6495246ac945ce74b88e72f82
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Background Cholesterol (CHO) is an essential component of the body. However, high CHO levels in the body can damage bone mass and promote osteoporosis. CHO accumulation can cause osteoblast apoptosis, which has a negative effect on bone form
Externí odkaz:
https://doaj.org/article/556b5d2df53444e9b662809256fe3a4c
Akademický článek
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Autor:
Tingyu Wang, You Yu, Yinglong Ding, Ziying Yang, Shumin Jiang, Faxiong Gao, Shan Liu, Lianbo Shao, Zhenya Shen
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
BackgroundThoracic Aortic Dissection (TAD) is a life-threatening disease without effective drug treatments. The disruption of HASMCs homeostasis is one direct histopathologic alteration in TAD pathological process. Several miRNAs have been shown abno
Externí odkaz:
https://doaj.org/article/0054267349e34d8e8893eb1051626dad