Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Abbye E. McEwen"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Genetic data are rapidly becoming part of tumor classification and are integral to prognosis and predicting response to therapy. Current molecular tumor profiling relies heavily on tissue resection or biopsy. Tissue profiling has several disadvantage
Externí odkaz:
https://doaj.org/article/ad5b8864be614db787cdbb559f68af3d
Autor:
John B. Lynch, Elizabeth R. Brown, Alexander L. Greninger, Vanessa A. Makarewicz, Jared Castor, Shah A Mohamed Bakhash, Abbye E McEwen, Allison J Zelikoff, Pavitra Roychoudhury, Estella Whimbey, Seth M. Cohen, Catherine Liu, Adrienne Schippers, Meei-Li Huang, Nandita S Mani, Keith R. Jerome, Chloe Bryson-Cahn, Robert J. Livingston, Kathy Strand, Steven A. Pergam, Noah R. Baker
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Across 20 vaccine breakthrough cases detected at our institution, all 20 (100%) infections were due to variants of concern (VOCs) and had a median Ct of 20.2 (IQR, 17.1–23.3). When compared with 5174 contemporaneous samples sequenced in our laborat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf3c57f9b6eb30113c58faeb3f0a2115
https://doi.org/10.1093/cid/ciab581
https://doi.org/10.1093/cid/ciab581
Autor:
Alan F Rubin, Joseph K Min, Nathan J Rollins, Estelle Y Da, Daniel Esposito, Matthew Harrington, Jeremy Stone, Aisha Haley Bianchi, Mafalda Dias, Jonathan Frazer, Yunfan Fu, Molly Gallaher, Iris Li, Olivia Moscatelli, Jesslyn YL Ong, Joshua E Rollins, Matthew J Wakefield, Shenyi 'Sunny' Ye, Amy Tam, Abbye E McEwen, Lea M Starita, Vanessa L Bryant, Debora S Marks, Douglas M Fowler
A central problem in genomics is understanding the effect of individual DNA variants. Multiplexed Assays of Variant Effect (MAVEs) can help address this challenge by measuring all possible single nucleotide variant effects in a gene or regulatory seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a397c178d1ea7780c6b67b50ef68b5cf
https://doi.org/10.1101/2021.11.29.470445
https://doi.org/10.1101/2021.11.29.470445
Autor:
Meei-Li Huang, Shah A Mohamed Bakhash, Vanessa A. Makarewicz, Robert J. Livingston, Steven A. Pergam, Estella Whimbey, Pavitra Roychoudhury, Kathy Strand, Adrienne Schippers, Seth M. Cohen, Nandita S Mani, Elizabeth R. Brown, Noah R. Baker, Allison J Zellikoff, Catherine Liu, Abbye E McEwen, John B. Lynch, Jared Castor, Alexander L. Greninger, Keith R. Jerome, Chloe Bryson-Cahn
Across 20 vaccine breakthrough cases detected at our institution, all 20 (100%) infections were due to variants of concern (VOC) and had a median Ct of 20.2 (IQR=17.1-23.3). When compared to 5174 contemporaneous samples sequenced in our laboratory, V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3332ccbfb048446d77b331fd308ed07f
https://doi.org/10.1101/2021.05.23.21257679
https://doi.org/10.1101/2021.05.23.21257679
Autor:
Erica Y. Kao, Abbye E. McEwen, James K. Aden, Stephanie K. Schaub, Robert W. Ricciotti, Jose G. Mantilla
Publikováno v:
International Journal of Surgical Pathology. :106689692211056
Radiation-associated sarcomas are an uncommon complication of therapeutic radiation. However, their prevalence has increased with the more widespread use of this treatment modality. The clinical, pathologic and genetic characteristics of radiation-as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581dae511106659f315b192a317f3601
https://doi.org/10.1177/10668969221105626
https://doi.org/10.1177/10668969221105626
Publikováno v:
American Journal of Clinical Pathology. 149:S74-S75
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bf5cec69aea0db83135c9e4df40ec5b
https://doi.org/10.1093/ajcp/aqx121.174
https://doi.org/10.1093/ajcp/aqx121.174
Publikováno v:
American Journal of Clinical Pathology. 152:S31-S31
Introduction Glioblastoma multiforme (GBM) is the most aggressive and most common primary brain tumor. Treatment of GBM and other high-grade gliomas consists of surgical resection followed by radiation and temozolomide (TMZ) chemotherapy. TMZ alkylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9185b53b5e1b4d397984deddcca802f
https://doi.org/10.1093/ajcp/aqz112.059
https://doi.org/10.1093/ajcp/aqz112.059
Publikováno v:
Molecular Biology of the Cell
The cadherin–catenin complex mediates cell–cell adhesion at adherens junctions. Phosphorylation of E-cadherin in its β-catenin–binding domain promotes surface stability of E-cadherin and robust cell–cell adhesion.
E-cadherin is highly p
E-cadherin is highly p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4b53e9496d4a75de6b37680dd524bb
https://pubmed.ncbi.nlm.nih.gov/24966173
https://pubmed.ncbi.nlm.nih.gov/24966173
Autor:
Kimberly A Wilson, Matthew H. Porteus, Jiuli Zhang, Shondra M. Pruett-Miller, Abbye E. McEwen, Eric J. Kildebeck
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Recent studies have shown that zinc finger nucleases (ZFNs) are powerful reagents for making site-specific genomic modifications. The generic structure of these enzymes includes a ZF DNA-binding domain and nuclease domain (Fn) are separated by an ami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f71ead0d177dc44b5dd925ded13dff
http://www.sciencedirect.com/science/article/pii/S2162253116301445
http://www.sciencedirect.com/science/article/pii/S2162253116301445
Publikováno v:
Subcellular Biochemistry ISBN: 9789400741850
The cadherin/catenin complex organizes to form a structural Velcro that joins the cytoskeletal networks of adjacent cells. Functional loss of this complex arrests the development of normal tissue organization, and years of research have gone into tea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec9ec30a2937010a697cf1e102edf7e
https://doi.org/10.1007/978-94-007-4186-7_8
https://doi.org/10.1007/978-94-007-4186-7_8