Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Abby R. Thurm"'
Autor:
Connor H. Ludwig, Abby R. Thurm, David W. Morgens, Kevin J. Yang, Josh Tycko, Michael C. Bassik, Britt A. Glaunsinger, Lacramioara Bintu
SummaryViruses encode transcriptional regulatory proteins critical for controlling viral and host gene expression. Given their multifunctional nature and high sequence divergence, it is unclear which viral proteins can affect transcription and which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cadb535731ba6f2045ebb052c7a3a356
https://doi.org/10.1101/2022.12.16.520835
https://doi.org/10.1101/2022.12.16.520835
The Nonmonotonic Dose Dependence of Protein Expression in Cells Transfected with Self-Amplifying RNA
Publikováno v:
J Virol
Self-amplifying (sa) RNA molecules—“replicons”—derived from the genomes of positive-sense RNA viruses are receiving increasing attention as gene and vaccine delivery vehicles. This is because mRNA forms of genes of interest can be incorporate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0338842fe79f1ad8ef576ae17c7dbb78
https://doi.org/10.1128/jvi.01858-21
https://doi.org/10.1128/jvi.01858-21
Publikováno v:
Journal of virological methods.
Self-amplifying(sa) RNA molecules – “replicons” – derived from the genomes of positive-sense RNA are receiving increasing attention as gene and vaccine delivery vehicles. This is because mRNA forms of genes of interest can be incorporated int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2daf74d6fe18e02901601d1c9c79ea3
https://pubmed.ncbi.nlm.nih.gov/34852240
https://pubmed.ncbi.nlm.nih.gov/34852240
Autor:
Bon Q. Trinh, Pier Paolo Pandolfi, Alexander K. Ebralidze, Yanzhou Zhang, Pu Zhang, Rory Coffey, Maria Teresa Voso, Mahmoud A. Bassal, Philipp B. Staber, Li Ying, Annalisa Di Ruscio, Daniel G. Tenen, Abby R. Thurm, Francisco Marchi, Hong Zhang, Carmelo Gurnari, Gerwin Heller, Emiel van der Kouwe, Simone Ummarino, Henry Yang, Vladimir Espinosa Angarica, Emiliano Fabiani, Elena Levantini, Chan-Shuo Wu, Tuan M. Nguyen, Sisi Chen, Danielle Tenen
The mechanism underlying cell type-specific gene induction conferred by ubiquitous transcription factors as well as disruptions caused by their chimeric derivatives in leukemia is not well understood. Here we investigate whether RNAs coordinate with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30c33fe3d25c76151e8ca38183cf15ea
https://doi.org/10.1101/2020.07.24.220020
https://doi.org/10.1101/2020.07.24.220020
Publikováno v:
Biophys J
Unlike double-stranded DNA, single-stranded RNA can be spontaneously packaged into spherical capsids by viral capsid protein (CP) because it is a more compact and flexible polymer. Many systematic investigations of this self-assembly process have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da197d09e1c11c64dc4568efd520dd7
https://pubmed.ncbi.nlm.nih.gov/31514968
https://pubmed.ncbi.nlm.nih.gov/31514968
Autor:
Bon Q. Trinh, Pu Zhang, Chan-Shuo Guo, Ying Li, Annalisa Di Ruscio, Abby R. Thurm, Alexander K. Ebralidze, Junyan Zhang, Daniel G. Tenen, Henry Yang
Publikováno v:
Blood. 132:1281-1281
PU.1 is a master hematopoietic transcription factor and also a key tumor suppressor in acute myeloid leukemia (AML). Our lab previously identified a distal DNA element called the upstream regulatory element (URE) that conferred myeloid cell type-spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90d8a307022797ad3503f72f477a5393
https://doi.org/10.1182/blood-2018-99-120252
https://doi.org/10.1182/blood-2018-99-120252