Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Abby R Kroken"'
Autor:
Abby R Kroken, Naren Gajenthra Kumar, Timothy L Yahr, Benjamin E Smith, Vincent Nieto, Hart Horneman, David J Evans, Suzanne M J Fleiszig
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2, p e1010306 (2022)
The Pseudomonas aeruginosa toxin ExoS, secreted by the type III secretion system (T3SS), supports intracellular persistence via its ADP-ribosyltransferase (ADPr) activity. For epithelial cells, this involves inhibiting vacuole acidification, promotin
Externí odkaz:
https://doaj.org/article/f6b5c23595a64c07b96dce3bce31bbb9
Autor:
Abby R. Kroken, Keith A. Klein, Patrick S. Mitchell, Vincent Nieto, Eric J. Jedel, David J. Evans, Suzanne M. J. Fleiszig
Publikováno v:
mSphere, Vol 8, Iss 5 (2023)
ABSTRACT Pathogenesis of Pseudomonas aeruginosa infections can include bacterial survival inside epithelial cells. Previously, we showed that this involves multiple roles played by the type three secretion system (T3SS), and specifically the effector
Externí odkaz:
https://doaj.org/article/9a2305cf78cb4f40a150e3e1b8fe1296
Autor:
Naren G. Kumar, Vincent Nieto, Abby R. Kroken, Eric Jedel, Melinda R. Grosser, Mary E. Hallsten, Matteo M. E. Mettrucio, Timothy L. Yahr, David J. Evans, Suzanne M. J. Fleiszig
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Within epithelial cells, Pseudomonas aeruginosa depends on its type III secretion system (T3SS) to escape vacuoles and replicate rapidly in the cytosol. Previously, it was assumed that intracellular subpopulations remaining T3SS-negative (an
Externí odkaz:
https://doaj.org/article/4c4628428ee34575b5086aef923761fc
Autor:
Abby R Kroken, Keith A Klein, Patrick S Mitchell, Vincent Nieto, Eric J Jedel, David J Evans, Suzanne M J Fleiszig
Publikováno v:
bioRxiv
Pathogenesis ofPseudomonas aeruginosainfections can include bacterial survival inside epithelial cells. Previously, we showed this involves multiple roles played by the type three-secretion system (T3SS), and specifically the effector ExoS. This incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b6d78361454309d4de32e76e050714
https://europepmc.org/articles/PMC9948977/
https://europepmc.org/articles/PMC9948977/
Autor:
Naren G. Kumar, Vincent Nieto, Abby R. Kroken, Eric Jedel, Melinda R. Grosser, Mary E. Hallsten, Matteo M. E. Mettrucio, Timothy L. Yahr, David J. Evans, Suzanne M. J. Fleiszig
Publikováno v:
mBio, vol 13, iss 6
Within epithelial cells,Pseudomonas aeruginosadepends on its type three secretion system (T3SS) to escape vacuoles and replicate rapidly in the cytosol. Previously, it was assumed that intracellular subpopulations remaining T3SS-negative (and therefo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe524c36cae47467087f4f7d8be18cf
https://doi.org/10.1101/2022.10.07.511388
https://doi.org/10.1101/2022.10.07.511388
Autor:
Abby R. Kroken, Naren Gajenthra Kumar, Timothy L. Yahr, Benjamin E. Smith, Vincent Nieto, Hart Horneman, David J. Evans, Suzanne M. J. Fleiszig
Publikováno v:
PLoS pathogens, vol 18, iss 2
The Pseudomonas aeruginosa toxin ExoS, secreted by the type III secretion system (T3SS), supports intracellular persistence via its ADP-ribosyltransferase (ADPr) activity. For epithelial cells, this involves inhibiting vacuole acidification, promotin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28bf6a55ceab8de2b24eb871129710fa
https://pubmed.ncbi.nlm.nih.gov/35130333
https://pubmed.ncbi.nlm.nih.gov/35130333
Autor:
Diana M. Bautista, Abby R. Kroken, Orneika Flandrin, Vincent Nieto, Matteo M. E. Metruccio, David J. Evans, Rose Z. Hill, Ananya Datta, Stephanie Wan, Sophia Ma, Suzanne M. J. Fleiszig
Publikováno v:
FASEB J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol 35, iss 10
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol 35, iss 10
The cornea of the eye differs from other mucosal surfaces in that it lacks a viable bacterial microbiome and by its unusually high density of sensory nerve endings. Here, we explored the role of corneal nerves in preventing bacterial adhesion. Pharma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2bc313bfac70f4cfb7b4531791dba4
https://europepmc.org/articles/PMC8486357/
https://europepmc.org/articles/PMC8486357/
Autor:
Joseph P. Shovlin, Carol Lakkis, Caffery Be, Robin L. Chalmers, Charlotte E. Joslin, Abby R. Kroken, Eduardo C. Alfonso, Nicole Carnt, Oliver D. Schein, Fiona Stapleton, Loretta B Szczotka-Flynn, Sarah A. Collier, Elmer Y. Tu, Mark D. P. Willcox, Eric Pearlman, Cristina M. Schnider, Deborah S. Jacobs
Publikováno v:
Optometry and vision science : official publication of the American Academy of Optometry, vol 98, iss 3
Optom Vis Sci
Optom Vis Sci
Significance Think Tank 2019 affirmed that the rate of infection associated with contact lenses has not changed in several decades. Also, there is a trend toward more serious infections associated with Acanthamoeba and fungi. The growing use of conta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3692ebfcbf42e5e0177d28fcce347fd
https://escholarship.org/uc/item/7df0088n
https://escholarship.org/uc/item/7df0088n
Autor:
Abby R. Kroken, David J. Evans, Melinda R. Grosser, Matteo M. E. Metruccio, Mary E. Hallsten, Vincent Nieto, Benjamin E. Smith, Suzanne M. J. Fleiszig, Patrick Hagan
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
mBio, vol 10, iss 4
mBio, Vol 10, Iss 4, p e02880-18 (2019)
mBio
mBio, vol 10, iss 4
mBio, Vol 10, Iss 4, p e02880-18 (2019)
mBio
Host cell invasion can contribute to disease pathogenesis by the opportunistic pathogen Pseudomonas aeruginosa. Previously, we showed that the type III secretion system (T3SS) of invasive P. aeruginosa strains modulates cell entry and subsequent esca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023951458b78982b8b7741c7cb75ef82
https://journals.asm.org/doi/10.1128/mBio.02880-18
https://journals.asm.org/doi/10.1128/mBio.02880-18
Autor:
Stephanie Wan, Melinda R. Grosser, Matteo M. E. Metruccio, Suzanne M. J. Fleiszig, David J. Evans, Vincent Nieto, Abby R. Kroken
Publikováno v:
Prog Retin Eye Res
Contact lenses represent a widely utilized form of vision correction with more than 140 million wearers worldwide. Although generally well-tolerated, contact lenses can cause corneal infection (microbial keratitis), with an approximate annualized inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec206b8271aa3d8da48c78f041b4b6a6
https://doi.org/10.1016/j.preteyeres.2019.100804
https://doi.org/10.1016/j.preteyeres.2019.100804