Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Abby L West"'
Autor:
Beth M Carpenter, Abby L West, Hanan eGancz, Stephanie L Servetas, Oscar Q Pich, Jeremy J Gilbreath, Daniel R Hallinger, Mark H Forsyth, D Scott eMerrell, Sarah L. J. Michel
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Helicobacter pylori NikR (HpNikR) is a nickel dependent transcription factor that directly regulates a number of genes in this important gastric pathogen. One key gene that is regulated by HpNikR is ureA, which encodes for the urease enzyme. In vitro
Externí odkaz:
https://doaj.org/article/ae49c164d1034c96ba9789f812fe735d
Autor:
Beth M Carpenter, Hanan Gancz, Reyda P Gonzalez-Nieves, Abby L West, Jeannette M Whitmire, Sarah L J Michel, D Scott Merrell
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5369 (2009)
Helicobacter pylori is a significant human pathogen that has adapted to survive the many stresses found within the gastric environment. Superoxide Dismutase (SodB) is an important factor that helps H. pylori combat oxidative stress. sodB was previous
Externí odkaz:
https://doaj.org/article/0707432e9c2e4e6b9e37e9ba0e5e5a64
Autor:
Alexis M. Fakner, Abby L. West, Bijil Subhash, Nicholas M. Bedford, Michael S. Sellers, Mark H. Griep
Publikováno v:
Nanoscale. 13(2)
Elucidating the location of stabilized nanoclusters within their protein hosts is an existing challenge towards the optimized development of functional protein-nanoclusters. While nanoclusters of various metal compositions can be readily synthesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e61c62f398e5fa68ead0933fe7c5bc5
https://pubmed.ncbi.nlm.nih.gov/33393579
https://pubmed.ncbi.nlm.nih.gov/33393579
Autor:
Shashi P. Karna, Abby L. West, Elizabeth I. Maurer-Gardner, Nicole M. Schaeublin, Alexis M. Fakner, Daniel P. Cole, Saber M. Hussain, Mark H. Griep
Publikováno v:
ACS Applied Materials & Interfaces. 8:21221-21227
To date, the directed in situ synthesis of fluorescent gold nanoclusters (AuNCs) has only been demonstrated in cancerous cells, with the theorized synthesis mechanism prohibiting AuNC formation in nontumorigenic cell lines. This limitation hinders po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33351b7094452da2814d613715c779d2
https://doi.org/10.1021/acsami.6b06624
https://doi.org/10.1021/acsami.6b06624
Publikováno v:
IEEE Nanotechnology Magazine. 9:25-30
Protein-encapsulated gold nanocluster (P-AuNC) synthesis was first demonstrated in 2009 [1]. Initially, these P-AuNCs were used as cellular imaging agents as the protein shell surrounding the AuNC made them highly biocompatible. However, recent studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27a8a326c5f00a188c5a53da3486d1cc
https://doi.org/10.1109/mnano.2014.2373452
https://doi.org/10.1109/mnano.2014.2373452
Publikováno v:
Analytical Chemistry. 86:7377-7382
Here we present the synthesis of the enzyme DNase 1 stabilized gold nanoclusters (DNase 1:AuNCs) with core size consisting of either 8 or 25 atoms. The DNase 1:Au8NCs exhibit blue fluorescence whereas the DNase 1:Au25NCs are red emitting. In addition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::484583991adb9d97d5175ef52cffbb71
https://doi.org/10.1021/ac5005794
https://doi.org/10.1021/ac5005794
Autor:
Jeremy J. Gilbreath, Abby L. West, Sarah L. J. Michel, Oscar Q. Pich, D. Scott Merrell, Beth M. Carpenter
Publikováno v:
Journal of Bacteriology. 194:6490-6497
Helicobacter pylori is a highly successful pathogen that colonizes the gastric mucosa of ∼50% of the world's population. Within this colonization niche, the bacteria encounter large fluctuations in nutrient availability. As such, it is critical tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691985aa21a9edd2b187cc0aa0b80034
https://doi.org/10.1128/jb.01226-12
https://doi.org/10.1128/jb.01226-12
Autor:
Sarah E. Evans, Sarah L. J. Michel, Abby L. West, Lester G. Carter, Edwin Pozharski, Javier M. González, Hiro Tsuruta
Publikováno v:
Proceedings of the National Academy of Sciences. 109:5633-5638
Helicobacter pylori NikR ( Hp NikR) is a nickel-dependent transcription factor that regulates multiple genes in the H. pylori pathogen. There are conflicting data regarding the locations of the Ni(II) sites and the role of Ni(II) coordination in DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d9758d73c124b910939367fcb29410c
https://doi.org/10.1073/pnas.1120283109
https://doi.org/10.1073/pnas.1120283109
Autor:
Pedro E. M. Lopes, Franz J. St John, Sarah L. J. Michel, Alexander D. MacKerell, Abby L. West, Edwin Pozharski
Publikováno v:
Journal of the American Chemical Society. 132:14447-14456
The metalloregulatory protein NikR from Helicobacter pylori (HpNikR) is a master regulator of gene expression which both activates and represses specific genes in response to nickel availability. Here, we report the first crystal structure (at 2.37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23eb1f6f103bcc1d7d13615be0ac379f
https://doi.org/10.1021/ja104118r
https://doi.org/10.1021/ja104118r
Publikováno v:
Biochemistry. 48:527-536
HPNikR is a prokaryotic nickel binding transcription factor found in the virulent bacterium Helicobacter pylori. HPNikR regulates the expression of multiple genes as an activator or repressor, including those involved in nickel ion homeostasis, acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03cd0629fb0dce5edd212fb09da547d0
https://doi.org/10.1021/bi801481j
https://doi.org/10.1021/bi801481j