Výsledky vyhledávání - "Abby E. Odle"

RBD-mRNA vaccine induces broadly neutralizing antibodies against Omicron and multiple other variants and protects mice from SARS-CoV-2 challenge

Autor: Juan Shi, Jian Zheng, Xiujuan Zhang, Wanbo Tai, Abby E. Odle, Stanley Perlman, Lanying Du

Publikováno v: Translational Research. 248:11-21

Multiple SARS-CoV-2 variants are identified with higher rates of transmissibility or greater disease severity. Particularly, recent emergence of Omicron variant with rapid human-to-human transmission posts new challenges to the current prevention str

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd1daca67a8d734ff03ae035bf5f805a
https://doi.org/10.1016/j.trsl.2022.04.007

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A Glycosylated RBD Protein Induces Enhanced Neutralizing Antibodies against Omicron and Other Variants with Improved Protection against SARS-CoV-2 Infection

Autor: Juan Shi, Jian Zheng, Wanbo Tai, Abhishek K. Verma, Xiujuan Zhang, Qibin Geng, Gang Wang, Xiaoqing Guan, Moffat M. Malisheni, Abby E. Odle, Wei Zhang, Fang Li, Stanley Perlman, Lanying Du

Publikováno v: Journal of virology. 96(17)

SARS-CoV-2 has mutated frequently since its first emergence in 2019. Numerous variants, including the currently emerging Omicron variant, have demonstrated high transmissibility or increased disease severity, posing serious threats to global public h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b54dd682db0a2b29a214fb2f566c2aaa
https://pubmed.ncbi.nlm.nih.gov/35972290

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Exponential increase in neutralizing and spike specific antibodies following vaccination of COVID ‐19 convalescent plasma donors

Autor: Anna E. Merrill, Abby E. Odle, Myrl Holida, Kerry A. Dubay, C. Michael Knudson, Judith Leon, Aaron V. Locher, Molly A. Vickers, Laura Collins, Stanley Perlman, Alexandra Ehlers, Alan Sariol, Dena R. Voss

Publikováno v: Transfusion

Background With the recent approval of COVID‐19 vaccines, recovered COVID‐19 subjects who are vaccinated may be ideal candidates to donate COVID‐19 convalescent plasma (CCP). Case Series Eleven recovered COVID‐19 patients were screened to don

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e579ad2b047fcf45efc1471365532c6
https://doi.org/10.1111/trf.16401

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The development of Nanosota-1 as anti-SARS-CoV-2 nanobody drug candidates

Autor: Jian Shang, Joseph P. Gallant, Jian Zheng, Fang Li, Christopher Massey, Molly A. Vickers, Ke Shi, Aaron M. LeBeau, Lanying Du, Yushun Wan, Abby E. Odle, Stanley Perlman, Hideki Aihara, Wanbo Tai, Gang Ye

Publikováno v: eLife, Vol 10 (2021)

Combating the COVID-19 pandemic requires potent and low-cost therapeutics. We identified a series of single-domain antibodies (i.e., nanobody), Nanosota-1, from a camelid nanobody phage display library. Structural data showed that Nanosota-1 bound to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a9184a86044d1159b0852daa3c9da8
https://doi.org/10.7554/elife.64815

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Author response: The development of Nanosota-1 as anti-SARS-CoV-2 nanobody drug candidates

Autor: Jian Shang, Abby E. Odle, Joseph P. Gallant, Ke Shi, Molly A. Vickers, Yushun Wan, Lanying Du, Jian Zheng, Stanley Perlman, Hideki Aihara, Gang Ye, Christopher Massey, Aaron M. LeBeau, Fang Li, Wanbo Tai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c9db54cd0430500bd99e1195cfd5ec8
https://doi.org/10.7554/elife.64815.sa2

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An assessment of the impact of recommended anesthesia work area cleaning procedures on intraoperative SARS-CoV-2 contamination, a case-series analysis

Autor: Randy W. Loftus, Stanley Perlman, Franklin Dexter, Alysha D.M. Robinson, Abby E. Odle, Lance C Evans

Publikováno v: Journal of Clinical Anesthesia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007011ef264c05dce22bdf4627605a53
https://pubmed.ncbi.nlm.nih.gov/34098391

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Exponential increase in neutralizing and spike specific antibodies following vaccination of COVID-19 convalescent plasma donors

Autor: Aaron V. Locher, Judith Leon, Abby E. Odle, Anna E. Merrill, Myrl Holida, Alan Sariol, Dena R. Voss, Alexandra Ehlers, Molly A. Vickers, Kerry A. Dubay, C. Michael Knudson, Stanley Perlman, Laura Collins

BackgroundWith the recent approval of COVID-19 vaccines, recovered COVID-19 subjects who are vaccinated may be ideal candidates to donate COVID-19 convalescent plasma (CCP).Case SeriesThree recovered COVID-19 patients were screened to donate CCP. All

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e28699b296c54bf464219bd3a7bd7a63
https://doi.org/10.1101/2021.02.02.21250836

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The Development of a Novel Nanobody Therapeutic for SARS-CoV-2

Autor: Jian Shang, Aleksandra Drelich, Ke Shi, Stanley Perlman, Christopher Massey, Hideki Aihara, Chien Te K. Tseng, Lanying Du, Vivian Tat, Aaron M. LeBeau, Jian Zheng, Joseph P. Gallant, Yushun Wan, Gang Ye, Fang Li, Kempaiah Rayavara Kempaiah, Wanbo Tai, Abby E. Odle, Molly A. Vickers

Publikováno v: bioRxiv
article-version (status) pre
article-version (number) 1
eLife

Combating the COVID-19 pandemic requires potent and low-cost therapeutics. We identified a novel series of single-domain antibodies (i.e., nanobody), Nanosota-1, from a camelid nanobody phage display library. Structural data showed thatNanosota-1boun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09fbd8616f9f67a2414e0fb4437a568a
https://doi.org/10.1101/2020.11.17.386532

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