Zobrazeno 1 - 10
of 340
pro vyhledávání: '"Abbruscato, P."'
Autor:
Amel Karaa, Enrico Bertini, Valerio Carelli, Bruce Cohen, Gregory M. Ennes, Marni J. Falk, Amy Goldstein, Gráinne Gorman, Richard Haas, Michio Hirano, Thomas Klopstock, Mary Kay Koenig, Cornelia Kornblum, Costanza Lamperti, Anna Lehman, Nicola Longo, Maria Judit Molnar, Sumit Parikh, Han Phan, Robert D. S. Pitceathly, Russekk Saneto, Fernando Scaglia, Serenella Servidei, Mark Tarnopolsky, Antonio Toscano, Johan L. K. Van Hove, John Vissing, Jerry Vockley, Jeffrey S. Finman, Anthony Abbruscato, David A. Brown, Alana Sullivan, James A. Shiffer, Michelango Mancuso, on behalf of the MMPOWER-3 Trial Investigators
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Background As previously published, the MMPOWER-3 clinical trial did not demonstrate a significant benefit of elamipretide treatment in a genotypically diverse population of adults with primary mitochondrial myopathy (PMM). However, the pres
Externí odkaz:
https://doaj.org/article/9ee65de424ba47d7a85aadc248d7ce12
Autor:
Justis P. Ehlers, MD, Allen Hu, MD, David Boyer, MD, Scott W. Cousins, MD, Nadia K. Waheed, MD, Philip J. Rosenfeld, MD, PhD, David Brown, MD, Peter K. Kaiser, MD, Anthony Abbruscato, PharmD, Gui Gao, PhD, Jeffrey Heier, MD, Prema Abraham, Christopher Devine, Anita Schadlu, George Novalis, Derek Y. Kunimoto, John Parchue, Suk Jin Moon, Zachary Segal, Dennis Marcus, Paul Hahn, Eric Suan, Michael Lee, Victor Gonzalez, Michael A. Samuel, Sunil Patel, Patrick Williams, Brian B. Berger, Henry Kwong, Dante Pieramici, Eric W. Schneider, Yevgeniy Shildkrot, Mathew T. Witmer, Nathan Steinle, Carmelina Gordon, Daniel Learned, Patrick Higgins, Guruprasad Pattar, Vijay Khetpal, Robin Ross, Mark R. Barakat, Sun Young Lee Sjatkowski, David Lally, Troy Becker
Publikováno v:
Ophthalmology Science, Vol 5, Iss 1, Pp 100628- (2025)
Objective: This study evaluated the safety and efficacy of elamipretide in dry age-related macular degeneration (AMD) with noncentral geographic atrophy (GA). Design: ReCLAIM-2 was a prospective, phase II, randomized, placebo-controlled, double-maske
Externí odkaz:
https://doaj.org/article/7164fb5412894bafbf1cb11d512f531f
Autor:
Khondker Ayesha Akter, Sejal Sharma, Ali Ehsan Sifat, Yong Zhang, Dhaval Kumar Patel, Luca Cucullo, Thomas J. Abbruscato
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103266- (2024)
Despite the protective nature of the blood-brain barrier (BBB) and brain-protecting tissues, some types of CNS injury or stress can cause cerebral cytokine production and profound alterations in brain function. Neuroinflammation, which can also be ac
Externí odkaz:
https://doaj.org/article/8e6ad89b44a3464ea5ac836539fc01ab
Autor:
Sabrina Rahman Archie, Ali Ehsan Sifat, Yong Zhang, Heidi Villalba, Sejal Sharma, Saeideh Nozohouri, Thomas J. Abbruscato
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-17 (2023)
Abstract Electronic nicotine delivery systems (ENDS), also commonly known as electronic cigarettes (e-cigs) are considered in most cases as a safer alternative to tobacco smoking and therefore have become extremely popular among all age groups and se
Externí odkaz:
https://doaj.org/article/80c6cbfa8c6041fca8386f38d4ac512f
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Sabrina Rahman Archie, Ali Ehsan Sifat, David Mara, Yeseul Ahn, Khondker Ayesha Akter, Yong Zhang, Luca Cucullo, Thomas J. Abbruscato
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Despite the prevalence of the perception that electronic cigarettes (e-cig) are a safer alternative to tobacco smoke, growing concern about their potential toxic impact warrants adequate investigation focusing on special populations lik
Externí odkaz:
https://doaj.org/article/2d523f60846c479ca8955b182bdbd4dc
Autor:
Ali Ehsan Sifat, Sabrina Rahman Archie, Saeideh Nozohouri, Heidi Villalba, Yong Zhang, Sejal Sharma, Yashwardhan Ghanwatkar, Bhuvaneshwar Vaidya, David Mara, Luca Cucullo, Thomas J. Abbruscato
Publikováno v:
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-15 (2022)
Abstract Background The short and long-term health effects of JUUL electronic cigarette (e-Cig) are largely unknown and warrant extensive research. We hypothesized that JUUL exposure could cause cerebrovascular toxicities impacting the progression an
Externí odkaz:
https://doaj.org/article/696451fbefe141c0944ab743d3585158
Autor:
Brittany Hornby, William Reid Thompson, Mohammed Almuqbil, Ryan Manuel, Anthony Abbruscato, Jim Carr, Hilary J. Vernon
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-9 (2022)
Abstract Background Natural history studies are increasingly recognized as having an important role in drug development for rare diseases. A phase 3, observational, retrospective, and non-interventional study was designed to establish a natural histo
Externí odkaz:
https://doaj.org/article/e8832bd27a77474bb0ff3589b829e888