Zobrazeno 1 - 10 of 213 pro vyhledávání: '"Abbott, GW"'
1
beta Subunits Control the Effects of Human Kv4.3 Potassium Channel Phosphorylation
Autor: Abbott, GW
Publikováno v: Abbott, GW. (2017). beta Subunits Control the Effects of Human Kv4.3 Potassium Channel Phosphorylation. FRONTIERS IN PHYSIOLOGY, 8. doi: 10.3389/fphys.2017.00646. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/05d017sd
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::617933daaf94ac1add60946c263cb8b6
http://www.escholarship.org/uc/item/05d017sd
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2
beta Subunits Functionally Differentiate Human Kv4.3 Potassium Channel Splice Variants
Autor: Abbott, GW
Publikováno v: Abbott, GW. (2017). beta Subunits Functionally Differentiate Human Kv4.3 Potassium Channel Splice Variants. FRONTIERS IN PHYSIOLOGY, 8. doi: 10.3389/fphys.2017.00066. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/2r1395v7
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::fb20478e679a4f9facb8f51a8a4f4960
http://www.escholarship.org/uc/item/2r1395v7
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3
Remote Liver Ischemic Preconditioning Protects against Sudden Cardiac Death via an ERK/GSK-3 beta-Dependent Mechanism
Autor: Hu, Z, Hu, S, Yang, S, Chen, M, Zhang, P, Liu, J, Abbott, GW
Publikováno v: Hu, Z; Hu, S; Yang, S; Chen, M; Zhang, P; Liu, J; et al.(2016). Remote Liver Ischemic Preconditioning Protects against Sudden Cardiac Death via an ERK/GSK-3 beta-Dependent Mechanism. PLOS ONE, 11(10). doi: 10.1371/journal.pone.0165123. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7dw2849b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::02c5246062cc646b143e57f7d54669f3
http://www.escholarship.org/uc/item/7dw2849b
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4
Pharmacogenetic diversification by alternative translation initiation: Background channels to the fore: Commentary on Kisselbach et al., Br J Pharmacol 171: 5182-5194
Autor: Abbott, GW
Publikováno v: Abbott, GW. (2015). Pharmacogenetic diversification by alternative translation initiation: Background channels to the fore: Commentary on Kisselbach et al., Br J Pharmacol 171: 5182-5194. British Journal of Pharmacology, 172(18), 4591-4593. doi: 10.1111/bph.12630. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/1v38115r
Unanticipated complexity of drug-target interactions creates a headache for those attempting to rationalize and create simple models of antiarrhythmic action, but can also introduce opportunities for increased drug specificity, or for potentially adv
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http://www.escholarship.org/uc/item/1v38115r
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5
The KCNE2 K+ channel regulatory subunit: Ubiquitous influence, complex pathobiology
Autor: Abbott, GW
Publikováno v: Abbott, GW; & Abbott, GW. (2015). The KCNE2 K+ channel regulatory subunit: Ubiquitous influence, complex pathobiology. Gene. doi: 10.1016/j.gene.2015.06.061. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/0d0586z3
© 2015 Elsevier B.V. The KCNE single-span transmembrane subunits are encoded by five-member gene families in the human and mouse genomes. Primarily recognized for co-assembling with and functionally regulating the voltage-gated potassium channels, t
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http://www.escholarship.org/uc/item/0d0586z3
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6
KCNQ1, KCNE2, and Na+-coupled solute transporters form reciprocally regulating complexes that affect neuronal excitability
Autor: Abbott, GW, Tai, KK, Neverisky, DL, Hansler, A, Hu, Z, Roepke, TK, Lerner, DJ, Chen, Q, Liu, L, Zupan, B, Toth, M, Haynes, R, Huang, X, Demirbas, D, Buccafusca, R, Gross, SS, Kanda, VA, Berry, GT
Publikováno v: Abbott, GW; Tai, KK; Neverisky, DL; Hansler, A; Hu, Z; Roepke, TK; et al.(2014). KCNQ1, KCNE2, and Na+-coupled solute transporters form reciprocally regulating complexes that affect neuronal excitability. Science Signaling, 7(315). doi: 10.1126/scisignal.2005025. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7j82p53p
Na+-coupled solute transport is crucial for the uptake of nutrients and metabolic precursors, such as myo-inositol, an important osmolyte and precursor for various cell signaling molecules. We found that various solute transporters and potassium chan
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::19ecd24501f2bded53c958f635a9a756
http://www.escholarship.org/uc/item/7j82p53p
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7
Filamin a promotes dynamin-dependent internalization of hyperpolarization-activated cyclic nucleotide-gated type 1 (HCN1) channels and restricts Ihin hippocampal neurons
Autor: Noam, Y, Ehrengruber, MU, Koh, A, Feyen, P, Manders, EMM, Abbott, GW, Wadman, WJ, Baram, TZ
Publikováno v: Noam, Y; Ehrengruber, MU; Koh, A; Feyen, P; Manders, EMM; Abbott, GW; et al.(2014). Filamin a promotes dynamin-dependent internalization of hyperpolarization-activated cyclic nucleotide-gated type 1 (HCN1) channels and restricts Ihin hippocampal neurons. Journal of Biological Chemistry, 289(9), 5889-5903. doi: 10.1074/jbc.M113.522060. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8q05p828
The actin-binding protein filamin A (FLNa) regulates neuronal migration during development, yet its roles in the mature brain remain largely obscure. Here, we probed the effects of FLNa on the regulation of ion channels that influence neuronal proper
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::ca1056986bf51838b67fb7472a22feea
http://www.escholarship.org/uc/item/8q05p828
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8
Ion channels under the sun
Autor: Abbott, GW, Pitt, GS
Publikováno v: Abbott, GW; & Pitt, GS. (2014). Ion channels under the sun. FASEB Journal, 28(5), 1957-1962. doi: 10.1096/fj.14-0501ufm. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4gp520n2
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::b959bdf3f16d02441c4310a1aedddb8a
http://www.escholarship.org/uc/item/4gp520n2
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9
Antiarrhythmic Drugs
Autor: Abbott, GW, Levi, R
Publikováno v: Abbott, GW; & Levi, R. (2013). Antiarrhythmic Drugs. In Pharmacology and Physiology for Anesthesia: Foundations and Clinical Application. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4qd56716
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::2f3f06afd0b0e3daed3faaa8fbca2f2d
http://www.escholarship.org/uc/item/4qd56716
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10
Transcriptomic analysis reveals atrial KCNE1 down-regulation following lung lobectomy
Autor: Heerdt, PM, Kant, R, Hu, Z, Kanda, VA, Christini, DJ, Malhotra, JK, Abbott, GW
Publikováno v: Heerdt, PM; Kant, R; Hu, Z; Kanda, VA; Christini, DJ; Malhotra, JK; et al.(2012). Transcriptomic analysis reveals atrial KCNE1 down-regulation following lung lobectomy. Journal of Molecular and Cellular Cardiology, 53(3), 350-353. doi: 10.1016/j.yjmcc.2012.05.010. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8ds9n0k9
Lone atrial fibrillation (AF) is associated with various ion channel gene sequence variants, notably the common S38G loss-of-function polymorphism in the KCNE1 K+ channel ancillary subunit gene. New-onset postoperative AF (POAF) generally occurs 48-7
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http://www.escholarship.org/uc/item/8ds9n0k9
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