Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Abbna Kirupakaran"'
Autor:
Zizheng Li, Ibrar Siddique, Inesa Hadrović, Abbna Kirupakaran, Jiwen Li, Ye Zhang, Frank-Gerrit Klärner, Thomas Schrader, Gal Bitan
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Li et al. design and synthesize fluorescently labeled molecular tweezers to explore their internalization, intracellular localization, and mechanism of endocytosis in brain cells including neurons and astrocytes. The authors find that MTs are interna
Externí odkaz:
https://doaj.org/article/a8efc1bcc1c2445089da253cba6fbb65
Autor:
Alexander Höing, Abbna Kirupakaran, Christine Beuck, Marius Pörschke, Felix C. Niemeyer, Theresa Seiler, Laura Hartmann, Peter Bayer, Thomas Schrader, Shirley K. Knauer
Publikováno v:
Biomacromolecules. 23:4504-4518
Many natural proteins contain flexible loops utilizing well-defined complementary surface regions of their interacting partners and usually undergo major structural rearrangements to allow perfect binding. The molecular recognition of such flexible s
Autor:
Tatjana Weil, Abbna Kirupakaran, My-Hue Le, Philipp Rebmann, Joel Mieres-Perez, Leila Issmail, Carina Conzelmann, Janis A. Müller, Lena Rauch, Andrea Gilg, Lukas Wettstein, Rüdiger Groß, Clarissa Read, Tim Bergner, Sandra Axberg Pålsson, Nadja Uhlig, Valentina Eberlein, Heike Wöll, Frank-Gerrit Klärner, Steffen Stenger, Beate M. Kümmerer, Hendrik Streeck, Giorgio Fois, Manfred Frick, Peter Braubach, Anna-Lena Spetz, Thomas Grunwald, James Shorter, Elsa Sanchez-Garcia, Thomas Schrader, Jan Münch
Publikováno v:
JACS Au
The COVID-19 pandemic caused by SARS-CoV-2 presents a global health emergency. Therapeutic options against SARS-CoV-2 are still very limited but urgently required. Molecular tweezers are supramolecular agents that destabilize the envelope of viruses
Autor:
Frank-Gerrit Klärner, Jiwen Li, Inesa Hadrovic, Ye Zhang, Abbna Kirupakaran, Gal Bitan, Thomas Schrader, Zizheng Li, Ibrar Siddique
Publikováno v:
Communications Biology
Communications biology, vol 4, iss 1
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications biology, vol 4, iss 1
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Lysine-selective molecular tweezers are promising drug candidates against proteinopathies, viral infection, and bacterial biofilm. Despite demonstration of their efficacy in multiple cellular and animal models, important questions regarding their mec
Protein recognition by designed protein ligands is highly challenging, but bears great opportunities. Supramolecular chemists have recently been able to synthesize tailored ligands with remarkable protein recognition properties which are absent in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be56dbcf1cb8d2ac5bab104388a3b8d6
https://doi.org/10.1039/9781788019798-00161
https://doi.org/10.1039/9781788019798-00161