Výsledky vyhledávání - "Abbie R Bellamy"

Akademický článek

Correlation between herpes simplex virus neutralizing antibody titers determined by ELVIS cell and traditional plaque reduction assays.

Autor: Tamara P Blevins, Yinyi Yu, Robert B Belshe, Abbie R Bellamy, Lynda A Morrison

Publikováno v: PLoS ONE, Vol 14, Iss 4, p e0214467 (2019)

Preventive viral vaccine efficacy trials require large-scale sample analysis to quantitate immune responses and their correlation with infection outcomes. Traditional plaque reduction assays measure a functionally important form of humoral immunity,

Externí odkaz: https://doaj.org/article/a2bad8d5e186468ca1a99b4107e4e4a6

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Akademický článek

Safety and immunogenicity of investigational seasonal influenza hemagglutinin DNA vaccine followed by trivalent inactivated vaccine administered intradermally or intramuscularly in healthy adults: An open-label randomized phase 1 clinical trial.

Autor: Cristina Carter, Katherine V Houser, Galina V Yamshchikov, Abbie R Bellamy, Jeanine May, Mary E Enama, Uzma Sarwar, Brenda Larkin, Robert T Bailer, Richard Koup, Grace L Chen, Shital M Patel, Patricia Winokur, Robert Belshe, Cornelia L Dekker, Barney S Graham, Julie E Ledgerwood, VRC 703 study team

Publikováno v: PLoS ONE, Vol 14, Iss 9, p e0222178 (2019)

BackgroundSeasonal influenza results in significant morbidity and mortality worldwide, but the currently licensed inactivated vaccines generally have low vaccine efficacies and could be improved. In this phase 1 clinical trial, we compared seasonal i

Externí odkaz: https://doaj.org/article/773f84c8b2754fefbbb0e4d8279bce2c

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Akademický článek

DNA vaccine priming for seasonal influenza vaccine in children and adolescents 6 to 17 years of age: A phase 1 randomized clinical trial.

Publikováno v: PLoS ONE, Vol 13, Iss 11, p e0206837 (2018)

BACKGROUND:Children are susceptible to severe influenza infections and facilitate community transmission. One potential strategy to improve vaccine immunogenicity in children against seasonal influenza involves a trivalent hemagglutinin DNA prime-tri

Externí odkaz: https://doaj.org/article/67936566033b4b438ee217c20baa6439

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Akademický článek

DNA priming for seasonal influenza vaccine: a phase 1b double-blind randomized clinical trial.

Autor: Julie E Ledgerwood, Abbie R Bellamy, Robert Belshe, David I Bernstein, Srilatha Edupuganti, Shital M Patel, Phyllis Renehan, Thad Zajdowicz, Richard Schwartz, Richard Koup, Robert T Bailer, Galina V Yamshchikov, Mary E Enama, Uzma Sarwar, Brenda Larkin, Barney S Graham, VRC 701 study team

Publikováno v: PLoS ONE, Vol 10, Iss 5, p e0125914 (2015)

The efficacy of current influenza vaccines is limited in vulnerable populations. DNA vaccines can be produced rapidly, and may offer a potential strategy to improve vaccine immunogenicity, indicated by studies with H5 influenza DNA vaccine prime foll

Externí odkaz: https://doaj.org/article/7b85207306a74ff197a727e6b15c4f53

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Akademický článek

Baseline Levels of Influenza-Specific B Cells and T Cell Responses Modulate Human Immune Responses to Swine Variant Influenza A/H3N2 Vaccine

Autor: Lilin Lai, Nadine Rouphael, Yongxian Xu, Amy C. Sherman, Srilatha Edupuganti, Evan J. Anderson, Pamela Lankford-Turner, Dongli Wang, Wendy Keitel, Monica M. McNeal, Kaitlyn Cross, Heather Hill, Abbie R. Bellamy, Mark J. Mulligan

Publikováno v: Vaccines, Vol 8, Iss 1, p 126 (2020)

The cellular immune responses elicited by an investigational vaccine against an emergent variant of influenza (H3N2v) are not fully understood. Twenty-five subjects, enrolled in an investigational influenza A/H3N2v vaccine study, who received two dos

Externí odkaz: https://doaj.org/article/236e4fbc3f2a4411a7394329c571900c

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An evaluation of cytokine and cellular immune responses to heterologous prime-boost vaccination with influenza A/H7N7-A/H7N9 inactivated vaccine

Autor: Abbie R. Bellamy, George Makedonas, Robert L. Atmar, Wendy A. Keitel, David B. Corry, Kaitlyn Cross, Hana M. El Sahly

Publikováno v: Hum Vaccin Immunother

The immunologic mechanisms underlying the improved serologic responses to heterologous prime-boost avian influenza vaccination are unclear. An exploratory analysis of the immune responses following 1 dose of influenza A/H7N9 inactivated vaccine in su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e94a95f6a77cb683f371131d4f004eb
https://doi.org/10.1080/21645515.2020.1750910

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Effect of recent seasonal influenza vaccination on serum antibody responses to candidate pandemic influenza A/H5N1 vaccines: A meta-analysis

Autor: Delia Voronca, Mark Wolff, Abbie R. Bellamy, Heather Hill, Robert L. Atmar, Silke Paust, Wendy A. Keitel

Publikováno v: Vaccine. 37:5535-5543

Recent studies have suggested that among those receiving seasonal influenza vaccine (SIV), reduced immunogenicity is observed in recently vaccinated (RV; within the past season or 2) persons when compared with those not recently vaccinated (NRV). We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450e8158c6296ded43c87205b3421080
https://doi.org/10.1016/j.vaccine.2019.04.066

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Safety and immunogenicity of unadjuvanted subvirion monovalent inactivated influenza H3N2 variant (H3N2v) vaccine in children and adolescents

Autor: Flor M. Munoz, Wendy A. Keitel, Andrea A. Berry, Robert L. Atmar, David I. Bernstein, Christopher J. Harrison, Emmanuel B. Walter, Abbie R. Bellamy, Soju Chang, Barbara A. Pahud, C. Buddy Creech, Karen L. Kotloff, Edwin L. Anderson, Evan J. Anderson

Publikováno v: Vaccine. 37:5161-5170

Objective In response to the emergence of influenza viruses with pandemic potential, we evaluated a swine-origin influenza A/H3N2 variant (H3N2v) vaccine in children. Study design This multicenter phase II open-label study assessed the safety and imm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8d087dd49e1cb0daee49b5196d2930
https://doi.org/10.1016/j.vaccine.2019.07.085

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High dose trivalent influenza vaccine compared to standard dose vaccine in patients with rheumatoid arthritis receiving TNF-alpha inhibitor therapy and healthy controls: Results of the DMID 10-0076 Randomized Clinical Trial

Autor: Rebecca Tuetken, Abbie R. Bellamy, Sonnie Kim, Nancy Wagner, Jack T. Stapleton, Heather Hill, Patricia L. Winokur

Publikováno v: Vaccine

Introduction Subjects with rheumatoid arthritis (RA) receiving tumor necrosis factor-inhibiting (TNFi) therapies are at risk for severe influenza, and may respond less well to influenza vaccine. We examined the safety and immunogenicity of high dose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77c9d359ae53d4fd5212c6dbace9ce5
https://europepmc.org/articles/PMC7337238/

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Baseline Levels of Influenza-Specific B Cells and T Cell Responses Modulate Human Immune Responses to Swine Variant Influenza A/H3N2 Vaccine

Autor: Amy C Sherman, Nadine Rouphael, Heather Hill, Evan J. Anderson, Lilin Lai, Srilatha Edupuganti, Abbie R. Bellamy, Yongxian Xu, Kaitlyn Cross, Dongli Wang, Wendy A. Keitel, Mark J. Mulligan, Pamela Lankford-Turner, Monica M. McNeal

Publikováno v: Vaccines
Volume 8
Issue 1
Vaccines, Vol 8, Iss 1, p 126 (2020)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d84b3f2af256d6b248d753160798e55
https://pubmed.ncbi.nlm.nih.gov/32183105

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