Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Abbie Celniker"'
Autor:
Eric Furfine, Karen L Tubridy, Kathryn Golden, Fiona Soong, Gregory Zarbis-Papastoitsis, Marianne Magill, Michael H Goldstein, Jennifer Agahigian, Anne Marie Salapatek, Joseph Kovalchin, Gary Sternberg, Abbie Celniker
Publikováno v:
Eye & Contact Lens: Science & Clinical Practice. 41:145-155
OBJECTIVES Many allergic conjunctivitis (AC) patients are inadequately treated with conventional therapies or require steroids. EBI-005 was developed to address the late phase allergic response. This study's objectives were to evaluate two adapted cl
Autor:
Howard Hill, Abbie Celniker, Ben Lee, JoMarie Smolec, Richard Tacey, Russell Weiner, Marian Kelley, Masood Khan, Binodh DeSilva, Wendell C. Smith
Publikováno v:
Pharmaceutical Research. 20:1885-1900
With this publication a subcommittee of the AAPS Ligand Binding Assay Bioanalytical Focus Group (LBABFG) makes recommendations for the development, validation, and implementation of ligand binding assays (LBAs) that are intended to support pharmacoki
Autor:
Jeanine Shulok, Barry Greene, Mark Rolfe, Abbie Celniker, David P. Schenkein, Peter J Worland, Gary S. Gray, Jeffrey S. Ross, Karen Gray
Publikováno v:
Expert Review of Anticancer Therapy. 3:107-121
The recent clinical and commercial success of anticancer antibodies, such as rituximab (Rituxan) and trastuzumab (Herceptin) has created great interest in antibody-based therapeutics for hematopoietic malignancies and solid tumors. Given the likely l
Autor:
Binodh S. DeSilva, Jacqueline A. Gibbons, Jeffrey M. Sailstad, Robert F. Dillard, Ronald R. Bowsher, Abbie Celniker, Ann Watson, Ira Das, Jean W. Lee, Michael Kunitani, Steve Swanson, Wendell C. Smith, Shalini Gupta, Han Gunn, Russell Weiner, Richard Tacey, Rene J. A. Paulussen, Krys J. Miller, Gerald D. Nordblom, Michael Geier, Dean W. Knuth, Masood N. Khan, Daan J.A. Crommelin
Publikováno v:
Pharmaceutical Research. 18:1373-1383
Publikováno v:
Journal of Cardiovascular Pharmacology. 25:888-897
Because activation of the glycoprotein IIbIIIa (GPIIbIIIa) on platelets represents the final common pathway of platelet aggregation, inhibition of fibrinogen binding to the GPIIbIIIa complex provides an excellent target for inhibiting platelet aggreg
Autor:
James W. Overstreet, Abbie Celniker, David L. Hess, Stephen P. Boyers, Dennis R. Stewart, Jeffry R. Cragun, Bill L. Lasley
Publikováno v:
Clinical Endocrinology. 38:379-385
Objective We determined the ovarian response to human chorionic gonadotrophin (hCG) in terms of relaxin and progesterone secretion during the peri-implantation period of normal and failing pregnancies. We wished to test the hypotheses that relaxin pr
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 75:603-608
To determine the effects of exogenous insulin-like growth factor-I (IGF-I) and GH on IGF-binding proteins (IGFBP)-1, -2, and -3, six healthy nonobese adult volunteers underwent two 2-week periods of diet restriction (20 Cal/kg.day), and during the la
Autor:
Christine H. Albini, Margaret H. MacGillivray, Abbie Celniker, Teresa Quattrin, Ann Johanson, Barry M. Sherman, Nancy J. Hopwood, Barbara J Mills, Juan F. Sotos
Publikováno v:
Pediatric Research. 29:619-622
Twelve-h overnight urine and serum samples obtained simultaneously at 20-min intervals were assayed for growth hormone (GH). Ninety-one children, 5 to 16 y (Tanner stage 1 to 3) participated; group 1 were healthy children, group 2 were children with
Publikováno v:
Pharmaceutical Research. :1032-1038
Two forms of chemically synthesized human relaxin (hRlx and hRlx-2) were administered as 88 µg/kg intravenous bolus doses to pregnant and nonpregnant rhesus monkeys. No significant differences in pharmacokinetics were observed between pregnant and n
Autor:
Abbie Celniker, Masood Khan, Vinod P. Shah, Wendell C. Smith, John W. A. Findlay, Ben Lee, Ronald R. Bowsher, Stephen Keller, David Lansky, Richard Tacey, JoMarie Smolec, Mary Saltarelli, Binodh DeSilva, Howard Hill, Martin Ullmann, H. Thomas Karnes, Marian Kelly, Robert F. Dillard, Russell Weiner, Anthony Mire-Sluis, Valerie Quarmby
Publikováno v:
Pharmaceutical research. 22(9)
The development and validation of ligand binding assays used in the support of pharmacokinetic studies has been the focus of various workshops and publications in recent years, all in an effort to establish a guidance document for standardization of