Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Abbey Theiss"'
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54138 (2013)
Formalin fixation is a mainstay of modern histopathologic analysis, yet the practice is poorly standardized and a significant potential source of preanalytical errors. Concerns of workflow and turnaround time drive interest in developing shorter fixa
Externí odkaz:
https://doaj.org/article/d90b425d9cfa487c812d258e2df54f80
Autor:
Maria Westerhoff, Michael Otter, Heidi L. Kenerson, Raymond S. Yeung, Melissa L. Lerch, Geoffrey S. Baird, Abbey Theiss, David Chafin
Publikováno v:
Cell and Tissue Banking
Precision tissue diagnostics rely on high quality input specimens so that assay results are not affected by artifact, but advances in collection and processing of tissue specimens have lagged behind innovations in diagnostic assay development. Theref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529401494fe954f9dbbabd1daca468ec
https://doi.org/10.1007/s10561-019-09800-8
https://doi.org/10.1007/s10561-019-09800-8
Publikováno v:
Biopreservation and Biobanking
The development of precision testing for disease diagnosis has advanced medicine by specifically matching patients with drugs to treat specific diseases. High-quality diagnostics start with high-quality tissue specimens. The development and optimizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93dcc115806d7f2280b835e67ac9f860
https://doi.org/10.1089/bio.2018.0122
https://doi.org/10.1089/bio.2018.0122
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology
Supplemental Digital Content is available in the text.
Personalized medicine promises diagnosis and treatment of disease at the individual level and relies heavily on clinical specimen integrity and diagnostic assay quality. Preanalytics, the co
Personalized medicine promises diagnosis and treatment of disease at the individual level and relies heavily on clinical specimen integrity and diagnostic assay quality. Preanalytics, the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea00d6d64a996ccf13cd0d87c987a4da
http://europepmc.org/articles/PMC5359782
http://europepmc.org/articles/PMC5359782
Autor:
Melissa L. Lerch, Geoffrey S. Baird, Maria Westerhoff, Heidi L. Kenerson, Michael Otter, Abbey Theiss, David Chafin, Raymond S. Yeung
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Phosphoproteins are the key indicators of signaling network pathway activation. Many disease treatment therapies are designed to inhibit these pathways and effective diagnostics are required to evaluate the efficacy of these treatments. Phosphoprotei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09916bbaa495ca3ade6df13f0a90c4d7
https://pubmed.ncbi.nlm.nih.gov/32034185
https://pubmed.ncbi.nlm.nih.gov/32034185
Publikováno v:
Journal of medical imaging (Bellingham, Wash.). 3(1)
The preservation of certain labile cancer biomarkers with formaldehyde-based fixatives can be considerably affected by preanalytical factors such as quality of fixation. Currently, there are no technologies capable of quantifying a fixative's concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442a57129418ca2defd55f1f02d38f1c
https://pubmed.ncbi.nlm.nih.gov/26866049
https://pubmed.ncbi.nlm.nih.gov/26866049
Publikováno v:
The FASEB Journal. 28
Breast cancer can be categorized into molecular subtypes that respond to specific therapies based on the expression of three protein biomarkers: estrogen receptor (ER), progesterone receptor (PR), ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14924fbbaa73a3a47e6b3a94c4afc2c2
https://doi.org/10.1096/fasebj.28.1_supplement.lb483
https://doi.org/10.1096/fasebj.28.1_supplement.lb483
Autor:
David Chafin, Vinnie Petre, Jefferson Taft, Benjamin Stevens, Michael Otter, Daniel Bauer, Abbey Theiss
Publikováno v:
SPIE Proceedings.
Recently, it has been demonstrated that the preservation of cancer biomarkers, such as phosphorylated protein epitopes, in formalin-fixed paraffin-embedded tissue is highly dependent on the localized concentration of the crosslinking agent. This stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::571603466b6585e33981ae25bb61b750
https://doi.org/10.1117/12.2043972
https://doi.org/10.1117/12.2043972
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113608 (2014)
PLoS ONE
PLoS ONE
Phosphorylated signaling molecules are biomarkers of cancer pathophysiology and resistance to therapy, but because phosphoprotein analytes are often labile, poorly controlled clinical laboratory practices could prevent translation of research finding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b73495065ec4b9749bbf7c49e388e6
https://doi.org/10.1371/journal.pone.0113608
https://doi.org/10.1371/journal.pone.0113608
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 1, p e54138 (2013)
PLoS ONE, Vol 8, Iss 1, p e54138 (2013)
Formalin fixation is a mainstay of modern histopathologic analysis, yet the practice is poorly standardized and a significant potential source of preanalytical errors. Concerns of workflow and turnaround time drive interest in developing shorter fixa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87aca9ec2e0872d9ea24297fe1d24ca1
https://doi.org/10.1371/journal.pone.0054138
https://doi.org/10.1371/journal.pone.0054138