Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Abbey Saadey"'
Autor:
Kaitlin A. Read, Devin M. Jones, Srijana Pokhrel, Emily D. S. Hales, Aditi Varkey, Jasmine A. Tuazon, Caprice D. Eisele, Omar Abdouni, Abbey Saadey, Melissa R. Leonard, Robert T. Warren, Michael D. Powell, Jeremy M. Boss, Emily A. Hemann, Jacob S. Yount, Gang Xin, Hazem E. Ghoneim, Chan-Wang J. Lio, Aharon G. Freud, Patrick L. Collins, Kenneth J. Oestreich
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
The regulation and direction of CD4+ T cells into phenotypic and functional lineages is coordinated by a complex set of mechanisms. Here the authors show a role for Aiolos as a regulator of the CD4+ cytotoxic and T follicular helper lineages.
Externí odkaz:
https://doaj.org/article/db3616878fde4edbb2df4e62fd0817bd
Autor:
Kaitlin Read, Srijana Pokhrel, Devin M Jones, Abbey Saadey, Caprice Eisele, Robert T Warren, Patrick Collins, Hazem E. Ghoneim, Aharon Freud, Kenneth J Oestreich
Publikováno v:
The Journal of Immunology. 208:112.20-112.20
CD4+ T follicular helper (TFH) cells are critical for the generation of robust humoral immune responses, as they provide help to B cells to support the generation of both pathogen-neutralizing antibodies and long-lived plasma cell populations. To dat
Autor:
Kaitlin Read, Bharath Sreekumar, Michael Duane Powell, Devin M Jones, Srijana Pokhrel, Abbey Saadey, Patrick Collins, Hazem Ghoneim, Kenneth J Oestreich
Publikováno v:
The Journal of Immunology. 206:53.10-53.10
The Ikaros zinc finger (IkZF) protein Eos is a transcription factor with known roles in driving regulatory T cell (Treg) suppressive function. However, whether it regulates the differentiation of effector CD4+ T cell subsets is currently unknown. Her