Global phosphoproteomics reveals DYRK1A regulates CDK1 activity in glioblastoma cells.

Autor: Recasens A; Charles Perkins Centre and School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, 2006, Australia. ariadna.recasens@sydney.edu.au., Humphrey SJ; Charles Perkins Centre and School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Camperdown, NSW, 2006, Australia., Ellis M; Charles Perkins Centre and School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, 2006, Australia., Hoque M; Charles Perkins Centre and School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, 2006, Australia., Abbassi RH; Charles Perkins Centre and School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, 2006, Australia., Chen B; Charles Perkins Centre and School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, 2006, Australia., Longworth M; School of Chemistry, Faculty of Science, The University of Sydney, Camperdown, NSW, 2006, Australia., Needham EJ; Charles Perkins Centre and School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Camperdown, NSW, 2006, Australia., James DE; Charles Perkins Centre and School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Camperdown, NSW, 2006, Australia., Johns TG; Oncogenic Signalling Laboratory, Telethon Kids Institute, Perth Children's Hospital, 15 Hospital Avenue, Nedlands, WA, 6009, Australia., Day BW; QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, QLD, 4006, Australia., Kassiou M; School of Chemistry, Faculty of Science, The University of Sydney, Camperdown, NSW, 2006, Australia., Yang P; Charles Perkins Centre and School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, 2006, Australia.; Charles Perkins Centre and School of Mathematics and Statistics, Faculty of Science, The University of Sydney, Sydney, NSW, 2006, Australia.; Computational Systems Biology Group, Children's Medical Research Institute, University of Sydney, Westmead, NSW, 2145, Australia., Munoz L; Charles Perkins Centre and School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, 2006, Australia. lenka.munoz@sydney.edu.au.

Publikováno v: Cell death discovery [Cell Death Discov] 2021 Apr 16; Vol. 7 (1), pp. 81. Date of Electronic Publication: 2021 Apr 16.

Synthesis and in vitro evaluation of diverse heterocyclic diphenolic compounds as inhibitors of DYRK1A.

Autor: Zhou Q; School of Chemistry, The University of Sydney, New South Wales 2006, Australia., Reekie TA; School of Chemistry, The University of Sydney, New South Wales 2006, Australia., Abbassi RH; School of Medical Sciences, Discipline of Pathology and Charles Perkins Centre, The University of Sydney, New South Wales 2006, Australia., Indurthi Venkata D; School of Medical Sciences, Discipline of Pathology and Charles Perkins Centre, The University of Sydney, New South Wales 2006, Australia., Font JS; School of Medical Sciences, Discipline of Pharmacology, The University of Sydney, New South Wales 2006, Australia., Ryan RM; School of Medical Sciences, Discipline of Pharmacology, The University of Sydney, New South Wales 2006, Australia., Munoz L; School of Medical Sciences, Discipline of Pathology and Charles Perkins Centre, The University of Sydney, New South Wales 2006, Australia., Kassiou M; School of Chemistry, The University of Sydney, New South Wales 2006, Australia. Electronic address: michael.kassiou@sydney.edu.au.

Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2018 Dec 01; Vol. 26 (22), pp. 5852-5869. Date of Electronic Publication: 2018 Oct 28.

Development and Biological Evaluation of a Photoactivatable Small Molecule Microtubule-Targeting Agent.

Autor: Döbber A; School of Medical Sciences and Charles Perkins Centre, The University of Sydney, Sydney, NSW 2006, Australia.; Institute of Pharmacy, Christian-Albrechts-University of Kiel, Gutenbergstraße 76, 24118 Kiel, Germany., Phoa AF; School of Medical Sciences and Charles Perkins Centre, The University of Sydney, Sydney, NSW 2006, Australia., Abbassi RH; School of Medical Sciences and Charles Perkins Centre, The University of Sydney, Sydney, NSW 2006, Australia., Stringer BW; QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, QLD 4006, Australia., Day BW; QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, QLD 4006, Australia., Johns TG; Oncogenic Signalling Laboratory and Brain Cancer Discovery Collaborative, Centre for Cancer Research, Hudson Institute of Medical Research, 27-31 Wright Street, Clayton, VIC 3168, Australia.; Monash University, Wellington Road, Clayton, VIC 3800, Australia., Abadleh M; Institute of Pharmacy, Christian-Albrechts-University of Kiel, Gutenbergstraße 76, 24118 Kiel, Germany., Peifer C; Institute of Pharmacy, Christian-Albrechts-University of Kiel, Gutenbergstraße 76, 24118 Kiel, Germany., Munoz L; School of Medical Sciences and Charles Perkins Centre, The University of Sydney, Sydney, NSW 2006, Australia.

Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2017 Mar 15; Vol. 8 (4), pp. 395-400. Date of Electronic Publication: 2017 Mar 15 (Print Publication: 2017).