Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy

Autor: Mohammad Chehelgerdi, Matin Chehelgerdi, Milad Khorramian-Ghahfarokhi, Marjan Shafieizadeh, Esmaeil Mahmoudi, Fatemeh Eskandari, Mohsen Rashidi, Asghar Arshi, Abbas Mokhtari-Farsani

Publikováno v: Molecular Cancer, Vol 23, Iss 1, Pp 1-45 (2024)

Abstract The CRISPR system is a revolutionary genome editing tool that has the potential to revolutionize the field of cancer research and therapy. The ability to precisely target and edit specific genetic mutations that drive the growth and spread o

Externí odkaz: https://doaj.org/article/b0a07b646ad7494e99b114c432917022

Biodegradation of Carbon‐Based Nanomaterials: The Importance of 'Biomolecular Corona' Consideration

Autor: Iseult Lynch, Abbas Mokhtari-Farsani, Mehdi Mehrali, Masoud Hasany

Publikováno v: Mokhtari-Farsani, A, Hasany, M, Lynch, I & Mehrali, M 2022, ' Biodegradation of Carbon-Based Nanomaterials: The Importance of “Biomolecular Corona” Consideration ', Advanced Functional Materials, vol. 32, no. 6, 2105649 . https://doi.org/10.1002/adfm.202105649

It has been over a decade since oxidative enzymes were first used to degrade carbon-based nanomaterials (CBNs). Although enormous progress has been achieved in this field, many questions and problems remain unresolved that need to be answered to ushe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83494a1acaa7d58c5668850e16cf47d
https://doi.org/10.1002/adfm.202105649

Determination of the presence of Babesia species in blood samples of cattle, camel and sheep in Iran by PCR

Autor: Arman Koohi, Mohammad Chehelgerdi, Augustino Alfred Chengula, Faham Khamesipour, Abbas Mokhtari-Farsani, Abbas Doosti

Publikováno v: Archives of Biological Sciences, Vol 67, Iss 1, Pp 83-90 (2015)

Babesia species are protozoan parasites that parasitize the erythrocytes of domestic animals and humans, causing anemia in the host. The parasites cause a zoonotic disease known as babesiosis. Polymerase chain reaction (PCR) has proven to be very sen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0e05334086268663f5e45c0add3aef3
https://doi.org/10.2298/abs140410009k

Bovine herpesvirus type 5 in semen samples from bulls in Iran

Autor: Abbas Mokhtari-Farsani, Ali Sharifzadeh, Mohammad-Javad Namazi, Abbas Doosti

Publikováno v: Archives of Virology. 160:235-239

Bovine herpesvirus 5 (BoHV-5) is an important pathogen of the central nervous system and has already been described in the genital tract of cattle and in semen. This virus is responsible for sporadic epizootics of fatal meningoencephalitis of calves.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2839a7cdb08cee9c24ffebf9622930d
https://doi.org/10.1007/s00705-014-2272-3

WITHDRAWN: Presence of Qnr genes related to resistance to quinolones, first-, second-, and third-generation in diarrheagenic Escherichia coli

Autor: Zahra Mohammadalipour, Abbas Doosti, Abbas Mokhtari-Farsani

Publikováno v: Journal of Patient Safety & Infection Control.

Background: Resistance genes transferred by plasmids are important factors that can contribute to the occurrence of quinolone resistance, specifically in Escherichia coli strains. Methods: A total number of 117 diarrhoeagenic E. coli strains were tes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::872dd8f04b948daabc1147ccbe2eb55d
https://doi.org/10.1016/j.jpsic.2015.12.002