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Akademický článek

Ultrasound assisted synthesis of 3-alkynyl substituted 2-chloroquinoxaline derivatives: Their in silico assessment as potential ligands for N-protein of SARS-CoV-2

Autor: Shahinshavali, Shaik, Hossain, Kazi Amirul, Kumar, Abbaraju Venkata Durga Nagendra, Reddy, Alugubelli Gopi, Kolli, Deepti, Nakhi, Ali, Rao, Mandava Venkata Basaveswara, Pal, Manojit

Publikováno v: In Tetrahedron Letters 1 October 2020 61(40)

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Ultrasound assisted synthesis of 3-alkynyl substituted 2-chloroquinoxaline derivatives: Their

Autor: Shaik, Shahinshavali, Kazi Amirul, Hossain, Abbaraju Venkata Durga Nagendra, Kumar, Alugubelli Gopi, Reddy, Deepti, Kolli, Ali, Nakhi, Mandava Venkata Basaveswara, Rao, Manojit, Pal

Publikováno v: Tetrahedron Letters

Graphical abstract We report the in silico studies and ultrasound assisted Cu-catalyzed synthesis of 3-alkynyl substituted 2-chloroquinoxaline derivatives as potential ligands for N-protein of SARS-CoV-2.
Highlights • In silico studies were pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4c8f5777e01e22c45e203b3ef13d34b9
https://pubmed.ncbi.nlm.nih.gov/32868957

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An alternative route to the synthesis of N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxy ethyl)piperazin-1-yl)-2-methyl pyrimidin-4-yl)amino)thiazole-5-carboxamide

Autor: Abbaraju Venkata Durga Nagendra Kumar, K. Deepti, Suryadevara Vijayavardhini, M. V. Basaveswara Rao, Shaik Shahinshavali, Reddymasu Sireesha, S. Pulla Reddy

Publikováno v: Chemical Data Collections. 31:100590

The target compound, N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl) piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide can be achieved by coupling between 2-bromo-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide and 2-(4-(6-a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0bc73941ce80ed4145cfa671b9acc3f7
https://doi.org/10.1016/j.cdc.2020.100590

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