Clinicopathological and molecular landscape of 5-year IDH-wild-type glioblastoma survivors: A multicentric retrospective study.

Autor: Miele E; Department of Onco-Hematology, Cell Therapy, Gene Therapies and Hemopoietic Transplant, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy., Anghileri E; Neuro-Oncology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta (FINCB), Milan, Italy. Electronic address: elena.anghileri@istituto-besta.it., Calatozzolo C; Neuropathology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Lazzarini E; Basic and Translational Oncology Unit, Istituto Oncologico Veneto (IOV)-IRCCS, Padua, Italy., Patrizi S; Department of Onco-Hematology, Cell Therapy, Gene Therapies and Hemopoietic Transplant, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy., Ciolfi A; Molecular Genetics and Functional Genomics Research Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy., Pedace L; Department of Onco-Hematology, Cell Therapy, Gene Therapies and Hemopoietic Transplant, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy., Patanè M; Neuropathology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Abballe L; Department of Onco-Hematology, Cell Therapy, Gene Therapies and Hemopoietic Transplant, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy., Paterra R; Neuro-Oncology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta (FINCB), Milan, Italy., Maddaloni L; Neuro-Oncology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta (FINCB), Milan, Italy., Barresi S; Pathology Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy., Mastronuzzi A; Department of Onco-Hematology, Cell Therapy, Gene Therapies and Hemopoietic Transplant, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy., Petruzzi A; Neuro-Oncology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta (FINCB), Milan, Italy., Tramacere I; Department of Research and Clinical Development, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Farinotti M; Neuroepidemiology-Brain Cancer Registry, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Gurrieri L; Osteoncology and Rare Tumors Center, IRCCS Istituto Romagnolo Per Lo Studio Dei Tumori (IRST) Dino Amadori, Meldola, Italy., Pirola E; Department of Neurosurgery Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Scarpelli M; Neurology Unit, Azienda Ospedaliera Universitaria Integrata Verona, Italy., Lombardi G; Medical Oncology Unit 1, Istituto Oncologico Veneto IOV-IRCCS, Padua, Italy., Villani V; Neuro-Oncology Unit, IRCCS Istituto Nazionale Tumori Regina Elena, Rome, Italy., Simonelli M; Department of Oncology and Hematology Unit, IRCCS Humanitas Research Hospital, Rozzano, Italy; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Merli R; Neurosurgery Unit, ASST Papa Giovanni XXIII, Bergamo, Italy., Salmaggi A; Neurology Unit, Ospedale A. Manzoni, ASST Lecco, Italy., Tartaglia M; Molecular Genetics and Functional Genomics Research Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy., Silvani A; Neuro-Oncology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta (FINCB), Milan, Italy., DiMeco F; Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy; Department of Neurological Surgery, John Hopkins Medical School, Baltimore, MD, USA., Calistri D; Biosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, FC, Italy., Lamperti E; Neuro-Oncology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta (FINCB), Milan, Italy., Locatelli F; Department of Onco-Hematology, Cell Therapy, Gene Therapies and Hemopoietic Transplant, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy; Department of Life Sciences and Public Health, Catholic University of the Sacred Heart, Rome, Italy., Indraccolo S; Basic and Translational Oncology Unit, Istituto Oncologico Veneto (IOV)-IRCCS, Padua, Italy; Department of Surgery Oncology and Gastroenterology, University of Padua, Padua, Italy., Pollo B; Neuropathology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.

Publikováno v: Cancer letters [Cancer Lett] 2024 Apr 28; Vol. 588, pp. 216711. Date of Electronic Publication: 2024 Feb 27.

β-arrestin1-E2F1-ac axis regulates physiological apoptosis and cell cycle exit in cellular models of early postnatal cerebellum

Autor: Abballe, L., Alfano, V., Antonacci, C., Cefalo, M. G., Cacchione, A., Del Baldo, G., Pezzullo, M., Po, A., Moretti, M., Mastronuzzi, A., De Smaele, E., Ferretti, E., Locatelli, Franco, Miele, E.

Publikováno v: Frontiers in Cell and Developmental Biology. 11

Development of the cerebellum is characterized by rapid proliferation of cerebellar granule cell precursors (GCPs) induced by paracrine stimulation of Sonic hedgehog (Shh) signaling from Purkinje cells, in the external granular layer (EGL). Then, gra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e701703bf836596ee457944dcea03ccd
https://doi.org/10.3389/fcell.2023.990711

Patient- and xenograft-derived organoids recapitulate pediatric brain tumor features and patient treatments.

Autor: Lago C; Armenise-Harvard Laboratory of Brain Disorders and Cancer, CIBIO, Trento, Italy., Federico A; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Division of Paediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany., Leva G; Armenise-Harvard Laboratory of Brain Disorders and Cancer, CIBIO, Trento, Italy., Mack NL; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Division of Paediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany., Schwalm B; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Division of Paediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany., Ballabio C; Armenise-Harvard Laboratory of Brain Disorders and Cancer, CIBIO, Trento, Italy., Gianesello M; Armenise-Harvard Laboratory of Brain Disorders and Cancer, CIBIO, Trento, Italy., Abballe L; Department of Onco-Hematology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), Rome, Italy., Giovannoni I; Pathology Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy., Reddel S; Department of Onco-Hematology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), Rome, Italy., Rossi S; Pathology Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy., Leone N; Pathology Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy., Carai A; Neurosurgery Unit, Department of Neurosciences, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy., Mastronuzzi A; Department of Onco-Hematology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), Rome, Italy., Bisio A; Laboratory of Radiobiology, CIBIO, Trento, Italy.; Trento Institute for Fundamental Physics and Application, TIFPA, Trento, Italy., Soldano A; Department of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Trieste, Italy., Quintarelli C; Department of Onco-Hematology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), Rome, Italy., Locatelli F; Department of Onco-Hematology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), Rome, Italy.; Catholic University of the Sacred Heart, Rome, Italy., Kool M; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Division of Paediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Miele E; Department of Onco-Hematology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), Rome, Italy., Tiberi L; Armenise-Harvard Laboratory of Brain Disorders and Cancer, CIBIO, Trento, Italy.

Publikováno v: EMBO molecular medicine [EMBO Mol Med] 2023 Dec 07; Vol. 15 (12), pp. e18199. Date of Electronic Publication: 2023 Nov 30.

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Modeling Brain Tumors: A Perspective Overview of in vivo and Organoid Models.

Autor: Antonica F; Armenise-Harvard Laboratory of Brain Disorders and Cancer, Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy., Aiello G; Armenise-Harvard Laboratory of Brain Disorders and Cancer, Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy., Soldano A; Laboratory of Translational Genomics, Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy., Abballe L; Department of Pediatric Hematology/Oncology and Cellular and Gene Therapy, Bambino Gesù Children's Hospital, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), Rome, Italy., Miele E; Department of Pediatric Hematology/Oncology and Cellular and Gene Therapy, Bambino Gesù Children's Hospital, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), Rome, Italy., Tiberi L; Armenise-Harvard Laboratory of Brain Disorders and Cancer, Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy.

Publikováno v: Frontiers in molecular neuroscience [Front Mol Neurosci] 2022 May 30; Vol. 15, pp. 818696. Date of Electronic Publication: 2022 May 30 (Print Publication: 2022).