Liposomal Encapsulation of Polysaccharides (LEPS) as an Effective Vaccine Strategy to Protect Aged Hosts Against S. pneumoniae Infection

Autor: Manmeet Bhalla, Roozbeh Nayerhoda, Essi Y. I. Tchalla, Alexsandra Abamonte, Dongwon Park, Shaunna R. Simmons, Blaine A. Pfeifer, Elsa N. Bou Ghanem

Publikováno v: Frontiers in Aging, Vol 2 (2021)

Despite the availability of licensed vaccines, pneumococcal disease caused by the bacteria Streptococcus pneumoniae (pneumococcus), remains a serious infectious disease threat globally. Disease manifestations include pneumonia, bacteremia, and mening

Externí odkaz: https://doaj.org/article/131f469762134caaa478fa956ac4842f

Liposomal Encapsulation of Polysaccharides (LEPS) as an Effective Vaccine Strategy to Protect Aged Hosts Against

Autor: Manmeet, Bhalla, Roozbeh, Nayerhoda, Essi Y I, Tchalla, Alexsandra, Abamonte, Dongwon, Park, Shaunna R, Simmons, Blaine A, Pfeifer, Elsa N, Bou Ghanem

Publikováno v: Frontiers in aging. 2

Despite the availability of licensed vaccines, pneumococcal disease caused by the bacteria

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6789a6e42779aedea03bf7f45b375d34
https://pubmed.ncbi.nlm.nih.gov/35291600

Extracellular adenosine signaling reverses the age‐driven decline in the ability of neutrophils to kill Streptococcus pneumoniae

Autor: Manmeet Bhalla, Shaunna R. Simmons, Elsa N. Bou Ghanem, Sydney E. Herring, Alexsandra Abamonte, Sara E. Roggensack

Publikováno v: Aging Cell

Extracellular adenosine production by CD73 and signaling via A1 adenosine receptors is crucial for the ability of PMNs to kill engulfed Streptococcus pneumoniae. Aging is accompanied by changes in the extracellular adenosine pathway on PMNs which res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42cec5c0e66d0cb625edde857b783815
https://doi.org/10.1111/acel.13218

Extracellular adenosine signaling reverses the age‐driven decline in the ability of neutrophils to kill Streptococcus pneumoniae.

Autor: Bhalla, Manmeet, Simmons, Shaunna R., Abamonte, Alexsandra, Herring, Sydney E., Roggensack, Sara E., Bou Ghanem, Elsa N.

Publikováno v: Aging Cell; Oct2020, Vol. 19 Issue 10, p1-12, 12p

Liposomal Encapsulation of Polysaccharides (LEPS) as an Effective Vaccine Strategy to Protect Aged Hosts Against S. pneumoniae Infection.

Autor: Bhalla M; Department of Microbiology and Immunology, University at Buffalo, The State University of New York, Buffalo, NY, United States., Nayerhoda R; Department of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, NY, United States., Tchalla EYI; Department of Microbiology and Immunology, University at Buffalo, The State University of New York, Buffalo, NY, United States., Abamonte A; Department of Microbiology and Immunology, University at Buffalo, The State University of New York, Buffalo, NY, United States., Park D; Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, United States., Simmons SR; Department of Microbiology and Immunology, University at Buffalo, The State University of New York, Buffalo, NY, United States., Pfeifer BA; Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, United States.; Gene and Tissue Engineering Center, University at Buffalo, The State University of New York, Buffalo, NY, United States., Bou Ghanem EN; Department of Microbiology and Immunology, University at Buffalo, The State University of New York, Buffalo, NY, United States.

Publikováno v: Frontiers in aging [Front Aging] 2021; Vol. 2. Date of Electronic Publication: 2021 Dec 22.