Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Ab, Seymour"'
Autor:
Zhen L, Jiang S, Feng L, Na, Bright, Andrew Peden, Ab, Seymour, Ek, Novak, Elliott R, Mb, Gorin, Ms, Robinson, Rt, Swank
Publikováno v:
Europe PubMed Central
The pearl mouse is a model for Hermansky Pudlak Syndrome (HPS), whose symptoms include hypopigmentation, lysosomal abnormalities, and prolonged bleeding due to platelet storage pool deficiency (SPD). The gene for pearl has recently been identified as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::120240d1a6cbb3115498d0b4ee0f0a8b
https://pubmed.ncbi.nlm.nih.gov/10381507
https://pubmed.ncbi.nlm.nih.gov/10381507
Publikováno v:
Europe PubMed Central
Pancreatic adenocarcinoma is a major cause of cancer death, and yet little is known about its molecular pathogenesis. We identified p53 mutations in 19 (70%) of 27 primary pancreatic adenocarcinomas. Most were missense point mutations, and the mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5197b9c79b9464131ba928ab431f13b3
https://pubmed.ncbi.nlm.nih.gov/8187092
https://pubmed.ncbi.nlm.nih.gov/8187092
Autor:
Ab, Seymour, Rh, Hruban, Redston M, Carlos Caldas, Sm, Powell, Kw, Kinzler, Cj, Yeo, Se, Kern
Publikováno v:
Europe PubMed Central
Knowledge of the patterns of allelic loss has been useful in identifying the spectrum of the tumor suppressor genes involved in various tumor types. Such analyses in pancreatic carcinoma have been difficult due to the characteristic host desmoplastic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d10f6005250776799f4b5af79b581e96
https://pubmed.ncbi.nlm.nih.gov/8168108
https://pubmed.ncbi.nlm.nih.gov/8168108
Autor:
Sa, Hahn, Ab, Seymour, At, Hoque, Schutte M, Lt, Da Costa, Ms, Redston, Carlos Caldas, Cl, Weinstein, Fischer A, Cj, Yeo
Publikováno v:
Europe PubMed Central
p53 and MTS1 are known to be mutationally inactivated in pancreatic adenocarcinoma. Other tumor suppressor genes are likely also to play a role. To define chromosomal arms which may harbor additional tumor suppressor genes, we performed an extensive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::eedb91b9794063e236a4ec46d1f882f0
http://europepmc.org/abstract/med/7553647
http://europepmc.org/abstract/med/7553647
Autor:
St Martin T; Homology Medicines, Bedford, Massachusetts 01730., Seabrook TA; Homology Medicines, Bedford, Massachusetts 01730., Gall K; Homology Medicines, Bedford, Massachusetts 01730., Newman J; Homology Medicines, Bedford, Massachusetts 01730., Avila N; Homology Medicines, Bedford, Massachusetts 01730., Hayes A; Homology Medicines, Bedford, Massachusetts 01730., Kivaa M; Homology Medicines, Bedford, Massachusetts 01730., Lotterhand J; Homology Medicines, Bedford, Massachusetts 01730., Mercaldi M; Oxford Biomedica Solutions, Bedford, Massachusetts 01730., Patel K; Homology Medicines, Bedford, Massachusetts 01730., Rivas IJ; Homology Medicines, Bedford, Massachusetts 01730., Woodcock S; Homology Medicines, Bedford, Massachusetts 01730., Wright TL; Homology Medicines, Bedford, Massachusetts 01730., Seymour AB; Homology Medicines, Bedford, Massachusetts 01730., Francone OL; Homology Medicines, Bedford, Massachusetts 01730., Gingras J; Homology Medicines, Bedford, Massachusetts 01730 jgingras@homologymedicines.com.
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2023 May 10; Vol. 43 (19), pp. 3567-3581. Date of Electronic Publication: 2023 Mar 28.
Autor:
Smith LJ; Homology Medicines, Inc., 1 Patriots Park, Bedford, MA 01730, USA., Schulman LA; Homology Medicines, Inc., 1 Patriots Park, Bedford, MA 01730, USA., Smith S; Homology Medicines, Inc., 1 Patriots Park, Bedford, MA 01730, USA., Van Lieshout L; Homology Medicines, Inc., 1 Patriots Park, Bedford, MA 01730, USA., Barnes CM; Homology Medicines, Inc., 1 Patriots Park, Bedford, MA 01730, USA., Behmoiras L; Homology Medicines, Inc., 1 Patriots Park, Bedford, MA 01730, USA., Scarpitti M; Homology Medicines, Inc., 1 Patriots Park, Bedford, MA 01730, USA., Kivaa M; Homology Medicines, Inc., 1 Patriots Park, Bedford, MA 01730, USA., Duong KL; Homology Medicines, Inc., 1 Patriots Park, Bedford, MA 01730, USA., Benard LO; Homology Medicines, Inc., 1 Patriots Park, Bedford, MA 01730, USA., Ellsworth JL; Homology Medicines, Inc., 1 Patriots Park, Bedford, MA 01730, USA., Avila N; Homology Medicines, Inc., 1 Patriots Park, Bedford, MA 01730, USA., Faulkner D; Homology Medicines, Inc., 1 Patriots Park, Bedford, MA 01730, USA., Hayes A; Homology Medicines, Inc., 1 Patriots Park, Bedford, MA 01730, USA., Lotterhand J; Homology Medicines, Inc., 1 Patriots Park, Bedford, MA 01730, USA., Rivas JI; Homology Medicines, Inc., 1 Patriots Park, Bedford, MA 01730, USA., Sengooba AV; Homology Medicines, Inc., 1 Patriots Park, Bedford, MA 01730, USA., Tzianabos A; Homology Medicines, Inc., 1 Patriots Park, Bedford, MA 01730, USA., Seymour AB; Homology Medicines, Inc., 1 Patriots Park, Bedford, MA 01730, USA., Francone OL; Homology Medicines, Inc., 1 Patriots Park, Bedford, MA 01730, USA.
Publikováno v:
Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2022 Jun 30; Vol. 26, pp. 224-238. Date of Electronic Publication: 2022 Jun 30 (Print Publication: 2022).
Autor:
Wei R; Proteomics, Translational Science, Biogen Idec, 14 Cambridge Center, Cambridge, MA, 02142, USA, ru.wei@biogenidec.com., Li G, Seymour AB
Publikováno v:
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2014; Vol. 1198, pp. 171-99.
Autor:
Malfait AM; Department of Biochemistry/ Internal Medicine, Rush University Medical Center, Chicago, Illinois 60612, USA. anne-marie_malfait@rush.edu, Seymour AB, Gao F, Tortorella MD, Le Graverand-Gastineau MP, Wood LS, Doherty M, Doherty S, Zhang W, Arden NK, Vaughn FL, Leaverton PE, Spector TD, Hart DJ, Maciewicz RA, Muir KR, Das R, Sorge RE, Sotocinal SG, Schorscher-Petcu A, Valdes AM, Mogil JS
Publikováno v:
Annals of the rheumatic diseases [Ann Rheum Dis] 2012 Jun; Vol. 71 (6), pp. 1042-8. Date of Electronic Publication: 2012 Mar 22.
Autor:
Guey LT; Applied Quantitative Genotherapeutics, Pfizer Pharmaceuticals, Cambridge, Massachusetts, USA., Pullinger CR, Ishida BY, O'Connor PM, Zellner C, Francone OL, Laramie JM, Naya-Vigne JM, Siradze KA, Deedwania P, Redberg RF, Frost PH, Seymour AB, Kane JP, Malloy MJ
Publikováno v:
The American journal of cardiology [Am J Cardiol] 2011 Aug 01; Vol. 108 (3), pp. 360-6.
Autor:
Guey LT; Applied Quantitative Genotherapeutics, Pfizer Biotherapeutics, Cambridge, MA 02144, USA., Kravic J, Melander O, Burtt NP, Laramie JM, Lyssenko V, Jonsson A, Lindholm E, Tuomi T, Isomaa B, Nilsson P, Almgren P, Kathiresan S, Groop L, Seymour AB, Altshuler D, Voight BF
Publikováno v:
Genetic epidemiology [Genet Epidemiol] 2011 May; Vol. 35 (4), pp. 236-46.